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Domain: theness.com
Stories and comments across the archive that link to theness.com.
Stories · 2
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Registered Clinical Trials Make Positive Findings Vanish
schwit1 writes: The requirement that medical researchers register in detail the methods they intend to use in their clinical trials, both to record their data as well as document their outcomes, caused a significant drop in trials producing positive results. From Nature: "The study found that in a sample of 55 large trials testing heart-disease treatments, 57% of those published before 2000 reported positive effects from the treatments. But that figure plunged to just 8% in studies that were conducted after 2000. Study author Veronica Irvin, a health scientist at Oregon State University in Corvallis, says this suggests that registering clinical studies is leading to more rigorous research. Writing on his NeuroLogica Blog, neurologist Steven Novella of Yale University in New Haven, Connecticut, called the study "encouraging" but also "a bit frightening" because it casts doubt on previous positive results."
In other words, before they were required to document their methods, research into new drugs or treatments would prove the success of those drugs or treatment more than half the time. Once they had to document their research methods, however, the drugs or treatments being tested almost never worked. The article also reveals a failure of the medical research community to confirm their earlier positive results. It appears the medical research field has forgotten this basic tenet of science: A result has to be proven by a second independent study before you can take it seriously. Instead, they would do one study, get the results they wanted, and then declare success. -
Is the End of Government Acceptance of Homeopathy In Sight?
cold fjord writes: It looks like homeopathy is in for a rough stretch ahead as shown in a chart and noted by Steven Novella at NEUROLoOGICAblog, "Homeopathy is perhaps the most obviously absurd medical pseudoscience. It is also widely studied, and has been clearly shown to not work. Further, there is a huge gap in the public understanding of what homeopathy is; it therefore seems plausible that the popularity of homeopathy can take a huge hit just by telling the public what it actually is. ... In 2010 the UK House of Commons Science and Technology Committee completed a full report on homeopathy in which they concluded it is witchcraft – that it cannot work, it does not work, and support for homeopathy in the national health service should be completely eliminated. In 2015 the Australian government completed its own review, concluding that there is no evidence that homeopathy works for anything. Homeopathy is a placebo. ... The FDA and the FTC in the United States are now both receiving testimony, questioning their current regulation of homeopathy. ... There is even a possibility that the FDA will decide to do their actual job – require testing of homeopathic products to demonstrate efficacy before allowing them on the market. If they do this simple and obvious thing, the homeopathic industry in the US will vanish over night, because there is no evidence to support any homeopathic product for any indication." — More on the FDA hearings at Science-Based Medicine.