Celera Has Assembled Complete Mouse Genome

Ant writes: "Celera Genomics said Friday that it has completed the assembly of the mouse genome. The genetics research company, which began the sequencing process a year ago, said its map now ensures greater than 99 percent representation of the genome." From rice to mice to humans, the mapping continues.

Comments

Is my parallel right?

[Anonymous Coward]

Sequencing a genome is a bit like converting a close-source binary to C-code with comments. Now every geneticist can hack the mouse genome and compile new mice!

Re:Is my parallel right?

[diaphanous]

Actually sequencing a genome alone, particularly a eukaryote (an organism that has cells with a chromosomes, a nucleus, cytoskeleton, endomembrane system, etc) doesn't get you that much. It's more like using a disassembler on a massive binary that is full of functions that don't actually do anything (junk DNA, introns). You could look at the dump, and figure out how a few algorithms work, but it doesn't tell you much about the program works as a whole.

Sequencing does allow to get started on the more scientificly interesting work of studying the phylogeny (evolutionary history) and expression of genes

Licensing?

[Anonymous Coward]

Will Celera Genomics release the genome as opensource? or will it be closed? And when will this be availble for download?

Re:Licensing?

[diaphanous]

Sadly, given Celera's past history, it will almost certainly be proprietary. Although they have benefited immensely from government funded research and data collection, they have refused to make their sequence data publicly available in GenBank. Most journals require you to publish your sequence data in GenBank as a condition for publication of papers related to the sequence data. Celera was granted a special exemption to this policy by Science when they published their paper on the human genome recently and I anticipate a similar special exemption will be allowed for the mouse data as well, though I haven't closely followed what's going on with the mouse genome, since I work on Acetabularia Acetabulum (this is my professor's web page, not mine, the views expressed here are not ...and so on)

If you want to analyze publicly available gene sequence data, you can use GenBank at NCBI and software from Bioinformatics.org. There is also a great directory of online molecular biology tools and information here

All your base pair

[Anonymous Coward]

are belong to us!

Important Genes

[XPulga]

I hope this allows scientists to determine which genes determine whether the mouse is opto-mechanical or fully optical, those that determine the number of buttons and especially those that determine the resolution. I guess determining if the connector will be serial or mini-DIN is quite straight-forward, but I hope they have mapped these genes too.

Oh, wait, I do remember someone saying something about a living rodent named after pointing devices...

My serial is faster and on the left.

[pubudu]

How would we do that, exactly? We may have the commented C-code, but to take your analogy a step further, we lack a keyboard (fast, reliable way to change), compiler (proteome), and the ability to program in anything more than Basic (maybe Pascal for the really good geneticists).

Re:And mice everywhere ...

[JoeGee]

I see a new movie ...

"The Boys from Disney"

A classroom full of Jeremy's. A teacher who looks suspiciously like Michael Eisner. The lyrics to "It's a Small World After All" written on the blackboard. Rows and rows of black ears ...

And mice everywhere ...

[JoeGee]

rejoice.

Please keep the work separate. I can see it now, a hacker breaking into Celera's systems causes the master genome files to be mingled. In 2021:

Mother: Doctor, I am so grateful this new genetic treatment saved little Jeremy's life, but I have one concern.

Doctor: What would that be?

Mother: Why does he look like Mickey Mouse?

Re:And mice everywhere ...

[glebite]

Little Jeremey will have to either go through radical surgery or face copyright infringement fines from D*sney...

Or even worse - become a living mascot...

Soo...

[Dancin_Santa]

When can we expect Mighty Mouse and Danger Mouse?

Dancin Santa