Slashdot Mirror


Stem Cell Symposium

Hypharse writes "The newly created Cable Science Network(who literally strives to be C-Span, but for science) has opened with a very informative session on Stem Cells. I have had great hope for this network since stations supposedly for science like the Discovery Channel and PBS have become much more show than substance. If this symposium is an example of their future offerings I would be very happy."

26 comments

  1. Political correctness by Pan+T.+Hose · · Score: 1, Insightful

    "I have had great hope for this network since stations supposedly for science like the Discovery Channel and PBS have become much more show than substance."

    Discovery Channel is trying to be politically correct so of course we are not going to see any truly uncensored scientific research results there until we overcome the "moral" outrage of uneducated people who are trying to stop us playing God for purely religious reasons. In my opinion, however, stem cell research is important, because when we are talking about a potential to save literally millions of human beings, I believe that ethics should always take precedence before morality.

    --
    Sincerely,
    Pan Tarhei Hosé, PhD.
    "Homo sum et cogito ergo odi profanum vulgus et libido."
    1. Re:Political correctness by ForestGrump · · Score: 1

      Agreed. There is much research that goes on, and the world CAN NOT come to terms with.

      Its fun and all to talk about DNA sequencing and ordering, but nobody really talks about how each gene's properties are discovered.

      Why? Because it's a fairly gruesome process. The easiest way is to find "patients" who suffer from some genetic disorder. Then compare their DNA with DNA from a someone who does not suffer from the genetic disease. Find the difference and that's assumed to be the gene trait.

      To understand genes of a lesser level, say some deformation that doesn't allow the fetus to come to term - such as if the bones of the body does not develop.
      our best ability to do so is to "knock out" the suspected gene with "junk DNA" and grow a fetus. If the fetus shows the deformity, then it is such gene.

      Gene research leads to alot of "mutants" but that's where it becomes fascinating- to create "gene defects" and find out what gene maps to what physical trait.

      NO, i'm no biologist, but I'm in pursuit of a BS in envi sci. And there is some talk about pollution and mutations.

      Grump

      --
      Is it true that more people vote for the winner of American Idol, than vote for the president? -Ali G.
    2. Re:Political correctness by xplenumx · · Score: 1
      What on earth are you talking about? As someone who engages in immunological/genetic research I can assure you that you're way off the mark.

      For starters, comparing the DNA of healthy normals to sick individuals is not a gruesome process. All it takes is a few CC of blood - and the draw is usually combined with the patients' routine blood draws. All patients (and healthy normals) have be informed exactly what the blood will be used for and must give consent. The doctors and scientists involved really do care, really want to help people, and work extremely hard to make things as humane and unintrusive as possible.

      Regarding gene knockouts - yes, we make gene knockout mice. These knockout mice have indirectly saved more lives than 911. No one is proposing that we do anything even remotly similar to humans - quite the opposite. Many of the most vocal criticals of 'designer babies' are scientists. Many of the most vocal critics of human cloning are scientists. Ironically, in my experience the largest proponents of these ideas are ill-informed people that have a misguided view of the dangers and benefits DNA manipulation and cloning.

    3. Re:Political correctness by balaam's+ass · · Score: 3, Insightful

      Hi. A couple questions:

      Why is believing that "the killing embryos in order to benefit other people is wrong" necessarily a religious position?

      Even if it were, what's wrong with having "religious reasons", as opposed to no reasons, or reasons of opportunism?

      Finally, if by ethics you mean how our actions affect other people, then you're really just begging the question. It is surely the ethics of killing these young humans that is the center of the debate.

    4. Re:Political correctness by cornjones · · Score: 1

      The more basic question is when does life start? When Johnny thinks about shtupping Susie? When Johnny Jr. moves out of the house and get's married?

      Well, probably somewhere in between those two. I would say when the fetus can sustain life on it's own.

      As such, stopping vital resarch that could better the quality of life for humanity (and better humanity itself) b/c of some attachment to a lump of cells is wrong.

      Besides, I don't think we are aborting babies for this. Correct me if I'm wrong but we are getting stems cells that are otherwise discarded in miscarriages and similar, right?

    5. Re:Political correctness by Anonymous Coward · · Score: 1, Interesting

      Doesn't God insert soul into an ovum during the fertilisation? I thought that was the only reason why people consider single cells "young humans"? No one says that few cells without any neural system can be conscious, feel pain or anything. But religious people believe it has a soul which inherits the original sin and if the soul disconnects from that body before it is baptized, the original sin is not forgiven and the sould cannot go to Heaven, and that is why it is better that living people die (pregnant women, Parkinson's disease victims, etc.) than embryos because those living people have already had a chance to have their sins forgiven. Isn't it true?

    6. Re:Political correctness by Anonymous Coward · · Score: 1, Insightful

      The more basic question is when does life start?

      This is not a correct question, even though I completely agree with your answers. The question is not when does life start because it is quite obvious that embryo is alive. But so is a sperm and ovum even before the fertilisation! Those are living cells, human cells. It doesn't mean anything though, since the skin cells I kill scratching myself are also living cells and are also human cells. The question is when we can call it a person. No one suggests that before the fertilisation. No one also says that after the birth. It must be somewhere between but it is a similar problem to that when a monkey started to be a person, a human being, during the evolution? (Let's forget for a while that most of people who consider a single cell to be a "human baby" usually don't believe in evolution.) The change is slow and fluent. See this comment for an explanation why Christians believe that killing a single cell can be worse than killing (or letting die) an adult person. They believe that it has a soul but because of the original sin it will go straight to hell. This fact is important to understand that in fact what they say is not inconsistent at all. The premise may be questioned (does the sould exist? does the original sin exist? does God exist?) but the following logic is consistent.

    7. Re:Political correctness by balaam's+ass · · Score: 2, Insightful

      I think the reason people consider them young humans is because they simply ARE. It's not a religious fact, it's just a matter of noting that these are humans in an early stage of development. The debate is over whether humans at this early stage are expendable (for the "good of the rest of society") or not.

      As for your description of the views of "religious people": Maybe you can find someone to advocate the position you describe, but I'm not sure many would identify with it, or even find it necessarily relevant.

    8. Re:Political correctness by Anonymous Coward · · Score: 0

      Oh, "they simply ARE". Now I get it! That will finally put an end to this debate when you explained it!

      Seriously, monkeys are also "humans in an early stage of development". Oh, I'm sorry, I forgot that you people don't believe in science and evolution...

    9. Re:Political correctness by clonan · · Score: 1

      AMEN Brother!!

      I am currently studying embryonic stem cells...the crap both parties are throwing around about the possibilities and problems is incredible!

      They are both off the mark!

    10. Re:Political correctness by Anonymous Coward · · Score: 0

      get's married

      "gets".

      life on it's own

      "its".

    11. Re:Political correctness by magefile · · Score: 1

      Besides, I don't think we are aborting babies for this. Correct me if I'm wrong but we are getting stems cells that are otherwise discarded in miscarriages and similar, right?

      That's the idea. Aborted fetuses are not suitable for these purposes, as I understand it. IVF embryos are much better. But since *all* new stem cell lines won't get federal funding ...

  2. I won't support EMBRYONIC stem cell research until by genrader · · Score: 3, Insightful

    I am in complete support of adult stem cell research, and it does have great potential. Embryonic stem cell research, though, I cannot support because a embryo is a human being with the same rights as anyone else. Killing one human to save another (Technically /more/ than one human to save another if it doesn't work well the first time) is immoral and stupid.

    I heard somewhere they are very close to being able to create stem cells without actually having conception with a sperm and an egg, if this is true I am in full support of it.

  3. Re:I won't support EMBRYONIC stem cell research un by ForestGrump · · Score: 0, Offtopic

    And what is your opinion of klling rats/mice for research? Due to their close relation to humans, much genetic research is done to mice/rats in order to get a better understanding of the human genome.

    What about insect research? The latest trend in neuro-toxins is for them to target insects specefically. The idea is that crops can be sprayed, insects eat crop and die. Humans eat crops and don't die.

    Bacterium research? Although bacteria are now 99% understood, is it approiate to exploit bacteria? Because of their simple nature, they can easily be altered to manufacture proteins that are critical in biological research.

    Lastly. Are you for euthanasia? I mean for humans and animals. For example, if YOUR FATHER/MOTHER was suffering from terminal lunch cancer and were on a severe pain management program. Their mental state would not be "fully there". Is it worth letting them suffer through the pain and not being mentally there to enjoy their last moments with you? Or is their physical and mental suffering acceptable if they can physically be present? I know that I would choose a "livable state of mind" over "physically present". I had previously decided it was time to call it quits when my dog could no longer walk on his own, and I would call the same decision for any other loved one.

    Grump.

    --
    Is it true that more people vote for the winner of American Idol, than vote for the president? -Ali G.
  4. Re:I won't support EMBRYONIC stem cell research un by Anonymous Coward · · Score: 0

    What about all those unneeded embryos being discarded (killed) in fertility clinics? Do we only have moral objections when we want to do something useful with them? They are being killed anyway, why can't scientists use them for research?

    If they can stop my descent into blindness I don't care how many dead embryos we have.

  5. Re:I won't support EMBRYONIC stem cell research un by xplenumx · · Score: 1
    What do you propose be done regarding all the frozen embryos held at fertility clinics?

    Clearly you can't support throwing them away. Then again, leaving them frozen forever would be no different than jailing someone for life for committing no crime (at some point the embroys will die while frozen). Given the sheer numbers (not to mention the lack of willing volunteer parents) you can't bring all these embryos to term.

    Unless a viable alternative is proposed to dealing with these embroys, it seems to me that leaving them frozen in fertility is far more immoral, stupid, and cruel than allowing the embryos to save their fellow humanity.

    How many embryos are you saving by not supporting stem cell research? Zero.

  6. Transplants? by Pan+T.+Hose · · Score: 1

    To understand genes of a lesser level, say some deformation that doesn't allow the fetus to come to term - such as if the bones of the body does not develop. our best ability to do so is to "knock out" the suspected gene with "junk DNA" and grow a fetus. If the fetus shows the deformity, then it is such gene.

    Would it be possible to grow a fetus not without bones but without a brain using a similar method? If so, would it be still considered unethical to perform experiments on it or use its organs for transplants even though it would be consciously equivalent to just any other organ, like heart or liver, taken from a patient after the death of his brain? Unlikely. The studies you are referring to should definitely continue, because one day it might provide a method for easy transplants. Today there are basically two most important problems with transplanting organs: finding an organ in the first place and avoiding the rejection. The surgery itself is already on a satisfactory level. Cloning the entire set of spare organs with patient's own DNA would be an amazing breakthrough and a sure Nobel Prize.

    --
    Sincerely,
    Pan Tarhei Hosé, PhD.
    "Homo sum et cogito ergo odi profanum vulgus et libido."
    1. Re:Transplants? by ForestGrump · · Score: 1

      I donm't know much about brain development.

      I know its possible to grow without bones, because i have a friend who works in a bio research lab at UCLA. Every now and then I can get him talking about the latest breakthroughs in the research industry.

      It might be possible to grow a clone without a head, I remember something about that on artbell (aka coast to coast am) a while back when dolly the sheep was still hot. but then AB has its load of wacked up stuff too.

      --
      Is it true that more people vote for the winner of American Idol, than vote for the president? -Ali G.
    2. Re:Transplants? by clonan · · Score: 1

      In theory....yes it is possible although we do not know how to do it or how to maintain homeostasis as it grows.

      But there are several significant problems with that method:

      #1 as I mentioned, no brain means no breathing and very poor heart rate etc. THe clone would ahve to be on total life support for its entier existence.

      #2 say you lost an arm, you would not want to then make a clone and let it grow up old enough so you can transplant an adult arm onto yours. This could take decades. Therefore you would have to get a clone made very early in life...thus it will be VERY expensive and storage would be an issue...on the of chance that you had an accident.

      #3 There is still the whole morality issue of...is it alive? etc

      I think a better way would be tissue engineering. You place various kinds of stem cells in a matrix that acts like an adult arm and over a few months the cells replace it and become the complete arm. No muss, no fuss but probably even harder than growing a clone with no head.

  7. Re:I won't support EMBRYONIC stem cell research un by hubs99 · · Score: 1

    Everyday I discard more human cells than exist in these embryos that are destroyed. I work in a hospital and the bronchoscopy lavage fluid that I handle contains millions of cells that are going to be cultured then destroyed.

    If you go to the doctors you will have millions and millions of cells disposed of for the purpose of preventing you from getting ill (Drawing blood).

    These cells that are bing destroyed everyday are no diffferent than the cells in an embryo. It does not hurt for these individual cells to die, If it did your skin would be crying in pain as you shed thousands of cells each day.

    What tend to forget is that a cell is a cell is a cell. A sperm uniting with a egg does not make the newly formed unit into something miraculous, it just reforms into a cell.

  8. Re:I won't support EMBRYONIC stem cell research un by xplenumx · · Score: 1
    Blood and skin cells are different from embryonic cells - that's why we need to engage in embryonic stem cell research.

    While we've been able to make psuedo-stem cell-like cells from adult cells, they do not act the same. Similarly, hematopoietic 'stem' cells are not the same as embryonic stem cells - not by a long shot.

    I see what you're saying, but be careful as the argument as you stated it would be used against stem cell research (if a cell is a cell is a cell, why use embryos?).

  9. Re:I won't support EMBRYONIC stem cell research un by hubs99 · · Score: 1

    That is true. I should have clarified. Once a cell differentiates it is almost impossible to get back to the state it was once in.

    My analogy would be that a skin/other cell is like a car while a stem cell is a box containing the raw materials to make a car.

    It is easy to make a car out of the raw materials but its nearly impossible to create a cadillac out of an Kia.

  10. Stem Cells - the political debate by Anonymous Coward · · Score: 0
    First, let me say that I have no problem with using any embryonic stem cells. I assign no more moral importance to a microscopic embryo destined never to implant in a uterine wall than I assign to blood cells drawn for a test in the doctor's office.

    Empirically, we can see a continuum between cells, and human being over the span of a gestation, and assigning an arbitrary cutoff point at which a fetus gets rights would be wrong. After all, How many rocks does it take to make a heap of rocks? How developed must a fetus be to be worthy of human compassion?

    Of course any fetus that will come to term should be accorded the same care and respect as the fully formed human being that it will become, but a fetus living in a test tube, and past it's 'expiration date' has no such future in store for it. It will never be more than a clump of cells.

    But in the case of the embryos that could potentially be used for embryonic stem cell research, the embryos are at the extreme left of the cells_in_petri_dish-->human_being continuum. While the case for ten rocks being a heap of rocks, may be wishy washy, it would be hard to argue that one rock constituted a heap. Lacking the potential to become more than a clump of cells, such an embryo fails the test for being human miserably.

    But the debate seems overblown. I will be voting against George Bush, but not because of this. The stem cell issue seems to be fairly unimportant incomparison to things like going to war against Iraq in response to an attack from alQueda. ( 200 billion so far = $800.00 from every man woman and child in the US. I certainly wouldn't have donated $800.00 to Iraqi Freedom voluntarily... ) Not to mention the effect of creating the atrocities that are inevitable in war and which are sure to swell the ranks of alQueda. The Iraq action, shows a profound ignorance of how to deal with terrorists. Terrorism is not about causing terror in and of itself - it's about causing terror in order to inspire panicked reprisals against the innocent which will inspire rage against the victim of terrorism, and swell the terrorists ranks. GWBush has shown himself to lack the neccessary coolheadedness to deal effectively with alQueda types.

    Is there a difference between embryonic stem cells and other stem cells? That seems to be the question that scientists want to answer by doing embryonic stem cell research. Why can't that question be answered using mouse stem cells? And if the answer turns out to be: "yes, there is a difference" unless there is a way to turn non-embryonic stem cells into embryonic stem cells, what is the use? Once someone is born, they won't be getting any more embryonic stem cells anyway, so there will be none available for any treatments.

  11. I'd love to watch... if I had access. by xplenumx · · Score: 1
    I'm in strong support the The Science Network (TSN), however will I ever be able to watch it? How much of the general public will be able (forget about willing) to even watch the programming?

    I can get PBS without access to cable. I can watch the Discovery Channel with basic cable. Will I have to increase my cable subscription in order to see the channel? While I would love this channel, I simply can't justify increasing my cable subscription from ~$10 per month to ~$40 per month for one channel.

    Best of luck to TSN - I'll just have to cheer from the sidelines.

  12. Re:I won't support EMBRYONIC stem cell research un by Idarubicin · · Score: 2, Interesting
    I cannot support because a embryo is a human being with the same rights as anyone else.

    What makes a human being?

    What endows it with rights?

    And are you sure that all human beings have the same rights?

    In the United States, adults are indeed endowed with a plethora of rights. Foreign nationals in the country--be they Saudi Arabian, Chinese, Mexican, British, or Canadian--are subject to arbitrary detention and deportation. ("Papers, please!") Criminals have been deprived of certain rights--freedom of movement, possibly even the right to their own lives--for the benefit of the rest of society. Children have a sharply circumscribed set of rights. Their parents or the state are empowered to make decisions on their behalf (including with respect to medical procedures), and to direct their actions.

    So to equate an embryo with a human being, and then blithely state that they are endowed with the full rights attendant to that status is a tad imprecise.

    A much more complicated question is the one of what constitutes a human being in the first place.

    As I read it, the parent has a very clearcut definition which suits him or her. Spermatazoans are not human, ova are not human. Once sperm fertilizes egg (bam!) that single fertilized cell is a human being.

    Okay. What if that bar is too low, or too high? What if--apologies to Monty Python--every sperm is sacred? I imagine that most Slashdot readers probably feel that sperm is disposable, but why should that be so? Every one is half of a potential baby; the same can be said for every unfertilized egg. This takes us to the strict Catholic doctrine that birth control is murder, and fornication for pleasure a sin.

    Going the other way things get quite complicated, too. After sperm meets egg, it still has a rough ride ahead. The newly-assembled embryo has to make its way from the oviduct to the lumen of the uterus, and eventually implant itself in the unterine lining. It undergoes several divisions during this process, and takes five or six days to do so.

    All through these early stages, the embryo is very vulnerable, and a significant fraction of them never make it. Indeed, spontaneous abortions in the first week or two are quite common. The body probably disposes of about half of all fertilized embroyos, either because a genetic defect is detected, or just because conditions aren't right--or plain old bad luck. Really, the body itself is quite cavalier about expelling embryos is doesn't like or doesn't want. (These early terminations are sometimes referred to as "chemical" pregnancies, because often only sensitive biochemical tests can reveal that they took place. The mother's period might be a bit late that month.)

    Jump ahead to about week 12. The major internal organ systems have appeared, though their function is for the most part quite limited. The fetus is a couple of inches long. At week 14 or so, eyelids, some musculature, fingernails, and sex organs have formed. The fetus begins to make spontaneous movements (albeit far too weakly for the mother to detect) and is about three inches long. The earliest surviving premature baby was born at about 22 weeks, if my memory serves. (There is a 50% chance of survival with extensive medical intervention at about the 26 week mark.) A full term pregnancy is about 40 weeks in length.

    A lot of people are content to not really think of the fetus as a "human being" until it has achieved some minimum level of development. Some peg it to the development of certain internal or external features (often around the end of the first trimester) while others apply a (shifting) target based on when a fetus is likely to be able to survive on its own. Maybe we should choose an early stage--the formation of a blastocyst (around the sixteen-cell stage) or the formation of the placenta (about four weeks, IIRC)?

    Then of course there's the question of in vitro fertilization. Common practice in many places is t

    --
    ~Idarubicin