M Prize For Anti-Aging Research Hits $1,000,000
Reason writes "William Haseltine of Human Genome Sciences (the 'father of regenerative medicine') has pushed the M Prize for anti-aging research - a project cofounded by biogerontologist Aubrey de Grey and Dave Gobel - over the $1,000,000 mark in pledges. Congratulations to all involved! Read the press release here."
There will never be a discovery (publically at least) of indefinitely life-extending consequence. There will, however, be discoveries that prolong life. But not too much at a time.
If you figure out a way to make people life forever or at least a very long time, you can only make them pay for it once. If you discover a way to make people live an extra decade, they'll pay through the nose for it, eventually die, move on and you'll have a new generation of customers.
It's just like medications and diseases. It's not in the interest of commercialized medicine to research and discover CURES. It's in their interest to research and discover medications that make living with a disease tolerable or prolong your life with the disease rather than eradicate it.
I'm sorry, but we are almost to the point of living too long as it is. There are way, way, way better causes to put that kind of money up for. Besides, the only people who will benefit from this are the very rich, which if you think about it are probably the people who are putting this money up in the first place.
Vain bastards. Thank god most of Africa probably doesn't know about this.
Per Square Mile, a blog about density
Wow, only 1million bucks to the person who cures natural death? No wonder why nobody is in a rush. You can make more money engineering bio weapons for the states. ;p
I can't help but notice that the most gung-ho anti-aging advocates are those entering a phase of life where they become painful aware and fearful of their own mortality. Nothing wrong with that, but they never just come out and say it.
I don't know about you, but if I discovered immortality, I certainly wouldn't tell anyone. Just imagine all those stupid people you know, hanging around you forever! *shudder* If I keep it a secret, then I'll be sure to outlive them. Eventually.
1) your mortality
2) what to do with your money before you go
Introducing the perfect solution.... Not only is it a nice "I'm helping humanity" sort of cause, but you also stand a chance of pushing that deadline out a bit.
For myself, I think a century in good health would be more than enough.
But maybe it's not nearly the idea of immortality, as the ability to choose when you're done.
Congratulations to all involved!
That would be... uh... all of us.
So, er, thanks.
Direct away from face when opening.
Anti-Gerasone- Cheap immortality comes to your neighborhood convenience store.
I can't wait for the cities to grow until there is no border between them.
the Boosterspice!!! Just think of how rich someone could get if they could live several lifetimes over.
"sweet dreams are made of this..."
One point which hasn't been made here yet is how the M Prizes are actually being awarded. These aren't one-time awards -- rather, a new cash award is given out each time the previous longevity record is broken, with the amount depending on how much the old record was beaten by.
The details from this page:
Longevity Prize (LP): details
The Longevity Prize is won whenever the world record lifespan for a mouse of the species most commonly used in scientific work, Mus musculus, is exceeded.
The amount won by a winner of PP is in proportion to the size of the fund at that time, but also in proportion to the margin by which the previous record is broken. The precise formula is:
Previous record: X days
New record: X+Y days
LP fund contains: $Z at noon GMT on day of death of record-breaker
Winner receives: $Z x (Y/(X+Y))
Thus, hypothetically, if the new record is twice the previous one, the winner receives half the fund. If the new record is 10% more than the old one, the winner receives 1/11 of the fund. The fund can thus never be exhausted, and the incentive to break the new record remains intact indefinitely. (This is in contrast to a structure that specifies a particular mouse age whose first achiever gets the whole fund.) We believe that this is important, because the public attention will be best maintained if there is a steady stream of record-breaks, showing that scientists are taking progressively better control of the aging process.
The record-breaker will receive prize money every week from the point where they beat the previous record. The amount paid each week will be as if their mouse had just died; the total amount won so far by a living record-breaker will be prominently displayed on the web site.
Rejuvenation Prize (RP): details
The Rejuvenation Prize rewards successful late-onset interventions. There are many ways to structure a prize to achieve this goal. The Rejuvenation Prize has been instituted (in replacement of the Reversal Prize -- see above) so as to satisfy two additional shortcomings of the Longevity Prize: first, that it is of limited scientific value to focus on a single mouse (a statistical outlier), and second, that the most important goal is to promote the development of interventions to restore youthful physiology, not merely to extend life. Thus, the Rejuvenation Prize rules are as follows:
1) The Rejuvenation Prize is awarded not for an individual mouse but for a published study. The study must satisfy the following criteria:
- The treated and control groups must have been at least 20 mice each.
- The intervention must have been begun at an age at least half of the eventual mean age at death of the longest-lived 10% of the CONTROL group.
- The treated mice must have been assessed for at least five different markers that change significantly with age in the controls, and there must be a statistically significant reversal in the trajectory of those five markers in the treated mice at some (unrestricted) time after treatment began versus some (also unrestricted) time before it began. (It is OK if other markers do not show this.)
2) The record that a new prizewinner has to beat should be the mean age at death of the longest-lived 10% of the treated group.
Conveniently, the Rejuvenation Prize does not require the same rigorous validation procedures as the Longevity Prize, because the age involved is defined to be that reported in the publication of the study.
Wouldn't flying to the stars be a lifestyle NOT designed to increase your lifespan? I mean, FTL travel is unlikely in the near future so you're faced with thousands of years of travel time to the nearest stars. That's thousands of years that you're doing what? Being frozen? While pretty much ANYTHING could go wrong with your ship? And what do you do when you get there? Say "Yep, it's a star! Time to go home!"? Then travel thousands of years back to an earth where the apes now rule the planet? Think I'll pass...
I'm trying to teach myself to set people on fire with my mind... Is it hot in here?
...this is old news...
/.?) that people who are 60 today may be the first people to hit 100 years old (based on a 0.001 % chance of dying each year - hence non-auto-mortal)
I heard recently (on
So in 20-25 they may bring together all reverse aging/ageing techniques.
I say MILF sites will have to be redefined!
#hostfile 0.0.0.0 primidi.com 0.0.0.0 www.primidi.com 0.0.0.0 radio.weblogs.com
You collect nothing?!? (Since the amount of money to pay is determined at the time of the mouse's death?)
Ben Hocking
Need a professional organizer?
It got that way partly because the math on which it was founded [men living to 60 if they are really lucky, women not working and popping off at 75] has been overturned by medical advances so now there's a shitload of oldsters who need a check every month.
boy would immortality or anything like it mess our society up!
SLASHDOT: news for people who can't concentrate on work or have no life at all and got tired of yelling back at the TV.
you don't need to solve immortality immediately. You need to extend your life long enough for technology to constantly improve the ability to extend and regenerate the body.
It is like surfing...just don't fall off, the sharks all have sickles and are voiced by Adam Carolla.
Hey, I'm just your average shit and piss factory.
i read, that has something to do with geans. each time your sell divide. a small part of the gean gets worned out to a small fragment and after a certain age and multiple division. the cell looses its capacity to divide. this cause aging.
So every decade, the economy and the demographics change... and "Social Security is in peril" headlines follow. A few minor changes and a lot of political posturing later and the headlines go away along with the problem. The only serious real problem with SS at this point is that the GOP wants to reorganize it in such a way that favored "approved" investment funds will receive worker contributions and collect percentages for fund managment. Bush wants to borrow $2T to finance the changeover.
If the GOP doesn't manage to put across their privatizing program, aka "guaranteed annual income for favored investment funds" scheme, a few minor adjustments will be made and SS will be good to go for another 10 years or so. I've seen this happen a couple or three times since I got into the workforce, and I'm not exactly excited about the "CRISIS". If SS isn't piratized, there isn't going to be a problem. Period. (If you trust Rush Limbaugh's economic analytis skills, let him invest your money... and let us know what happens)
This isn't to say that we need a privatized old-age pension scheme. The Thatcher government tried this in the Reagan era, the Brits found out that universal private old=age pension put a great many people into the market who have no business in it, and they're discussing remodeling their pension system using the US SS program as a model.
The adjustment for increased longevity is sort of obvious, raise the retirement age. People living a few centuries might wind up pursuing many careers, or getting very, very, very good at one.
Tech Public Policy stuff
Here's an article on the guy, with pics. Says he is not a real biologist though. http://www.slate.com/id/2115015/