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Lego Blocks Simulate Microfluidic Filters

BuzzSkyline writes "Researchers at Johns Hopkins University are playing with Lego blocks to discover how arrays of nanoscopic obstacles could sort cells and other tiny particles by size. Ball bearings dropped through an array of Lego pieces submerged in glycerin serve as an analogue of the tiny systems, with bearings of different sizes taking different paths through the array. An academic paper describing the Lego research recently appeared in the journal Physical Review Letters (subscription required)."

26 comments

  1. Meanwhile, by Anonymous Coward · · Score: 0

    Meanwhile, researchers at Country Bumpkin's Higher Edumacation facility attempted to recreate the experiment with "aftermarket" lego pieces submerged in Everclear.

    It goes without saying that the result of experiment caused the science department (located in Uncle Nillis's barn) to be evacuated whilst the fumes cleared out.

  2. Well as long as I don't have to reverse polarity by Anonymous Coward · · Score: 1, Funny

    Lego? Microfluidic Filters? Yeah and if I reverse the polarity on the main communications array, a tachyon pulse will be generated.

  3. Re:Well as long as I don't have to reverse polarit by thomasdz · · Score: 0, Offtopic

    Lego? Microfluidic Filters? Yeah and if I reverse the polarity on the main communications array, a tachyon pulse will be generated.

    FAIL: you forgot to mention the Heisenberg compensators and the plasma conduits.

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  4. Re:Well as long as I don't have to reverse polarit by weirdcrashingnoises · · Score: 5, Funny

    Nonsense, obviously the emergency capacitors would absorb any access energy created by the array. The only side effect was in they overloaded they would discharge through the main reactor core overloading several systems, possibly causing a flux in the hyper-drive which would create a tach...

    oh wait you are right.

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  5. How is this new? by Taibhsear · · Score: 1

    Biochemists already do this with proteins and other biochemicals and I'm sure other fields have done this with other things. Is this only new and exciting because legos are being used?

    1. Re:How is this new? by John+Hasler · · Score: 1

      This is entirely different. The particles come out of the filter at different places rather than at different times.

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  6. Re:Well as long as I don't have to reverse polarit by weirdcrashingnoises · · Score: 2, Funny

    wow...

    access = excess

    in = if

    me = just woke up, sorry about that.

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  7. Re:Well as long as I don't have to reverse polarit by simcop2387 · · Score: 0, Offtopic

    yea but he didn't mention the replicator and transporter systems.

  8. My date was really impressed by Anonymous Coward · · Score: 0

    ... until I told her "the neat thing" about how the experiments were done.

  9. its plinko by Anonymous Coward · · Score: 1, Funny

    http://en.wikipedia.org/wiki/Plinko
    its plinko

  10. Way Cool by Anonymous Coward · · Score: 1, Insightful

    I build microfluidic devices and man it can be time consuming to design fabricate and test them. To design a good device you have to draw up the design, fabricate it (often in a clean room) and then assemble and test it. With this I could just get a little slimy and in 30 minutes have a good idea if what I have is going to work...Now I just have to convince my boss I'm not just playing with Legos at work

  11. Re:Well as long as I don't have to reverse polarit by Anonymous Coward · · Score: 0

    And the inertial dampeners... never forget the inertial dampeners.

  12. Yes! by Anonymous Coward · · Score: 0

    Now when my wife asks why I waste my time with Legos I can tell her that I'm learning how to sort nano-particles in microfluidic arrays!

  13. Coin bank! by jollyreaper · · Score: 1

    Lurve those things.

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  14. I hate when headlines do this. by johnthorensen · · Score: 3, Interesting

    Reporters and the like are always trying to get an 'angle' obviously, but still - it's a little lame to emphasize the Lego portion of this. I love Legos, but let's face it - this apparatus could have been built out of many other things. The real 'science' behind this story is the construction of a scale model and details upon how the researchers were able to prove similitude between the large and micro scales. Not that pop sci articles aren't valuable, but using Lego as a hook to a legitimate science publication seems gimmicky.

    1. Re:I hate when headlines do this. by Speare · · Score: 1

      I love Legos, but let's face it - this apparatus could have been built out of many other things.

      The researcher answers the question:

      * Lego is available and accessible, moreso than developing tools or using ad hoc scavenged parts to make your own pegs
      * Lego is machined to fairly high standards of consistency and clean geometry, which helps this particular study

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    2. Re:I hate when headlines do this. by eh2o · · Score: 1

      Seems like it would be better to just simulate in on the computer. Legos submerged in glycerin sounds like a terrible mess.

  15. Legos Blocks by Anonymous Coward · · Score: 0

    Lego blocks, is there anything they can't do?

  16. Legos by R2.0 · · Score: 1

    Is there anything they can't do?

    (And I know the "proper" company defined term is Lego blocks. Fuck you.)

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    1. Re:Legos by Anonymous Coward · · Score: 0

      It's more that 'Legos' looks weird than about following a company rule.

      I spent my childhood playing with Lego, and never once saw it refered to as 'Legos' till I started reading Slashdot.

  17. Science CAN be fun! by Drakkenmensch · · Score: 1

    I'm impatiently waiting for Construx quantum physics and Lincoln Log genetics.

  18. Reducing the cost of research by.... by Anonymous Coward · · Score: 0

    ... Using Mega Bloks instead of Legos?

  19. Re:Well as long as I don't have to reverse polarit by LrdDimwit · · Score: 1

    Don't worry about it. You've already displayed more attention to detail than those involved with actually writing the dialog for the real show.