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Video Game-Like Programs Could Treat Schizophrenia

derGoldstein writes "Discovery is pointing to an ongoing study by Sophia Vinogradov, professor of psychiatry at UC-San Francisco, who is 'trying to determine whether computer-based cognitive remediation, a type of brain training through video game-like programs, is effective for treating schizophrenia. ... In a handful of blinded and randomized trials with computer-based training, Vinogradov has reported cognitive improvements for both recently diagnosed patients and those living with the disorder for several years. So far, treatment — such as 50 hours of training over a 10-week period — has shown great promise for patients when compared to control groups.'"

31 comments

  1. Discovery....Blah by Anonymous Coward · · Score: 0

    If "DIscovery" is posting about this, then it's immediately suspect.

    1. Re:Discovery....Blah by YodasEvilTwin · · Score: 1

      Yes, the evil Discovery Network. Convincing the world that the scientific method is "valid" since 1995.

    2. Re:Discovery....Blah by swanzilla · · Score: 2

      Hypothesis: Americans would watch a program about logging.
      Prediction: They will.
      Experiment: (see Discovery Channel lineup)
      Outcome: Americans will watch a program about logging. There exist several.

    3. Re:Discovery....Blah by derGoldstein · · Score: 1

      And what does National Geographic have to do with "Toughest Prisons"? They need to fill slots and they need to fill them with stuff at least some people will watch. It doesn't delegitimize other shows on the channel/s, and certainly not the organizations as a whole.

      --
      Entomologically speaking, the spider is not a bug, it's a feature.
    4. Re:Discovery....Blah by Anonymous Coward · · Score: 0

      "Toughest Prisons"
      Required learning in the penal states of america.

    5. Re:Discovery....Blah by CSMoran · · Score: 1

      I'd watch a good program on logging techniques and good practice myself. Like what you do when the disk is full and you can't log that.

      --
      Every end has half a stick.
  2. Re:Boy who was stuffed in oven: Don't jail my dad by YodasEvilTwin · · Score: 0

    The relevance of this post is astounding.

  3. Tangentially related by derGoldstein · · Score: 3, Insightful

    A blog post about mental illness and startups. In the case of some mental illnesses/conditions, behaviorism can play a bigger part than the chemistry. It's an absurdly difficult subject to research, and progress is slow, but mental illness is up there with obesity on the watch-list of developed-world epidemics.

    --
    Entomologically speaking, the spider is not a bug, it's a feature.
    1. Re:Tangentially related by istartedi · · Score: 1

      A blog post about mental illness and startups.

      My tweet along a similar line, from some time ago.

      --
      For all intensive purposes, "whom" is no longer a word. That begs the question, "who cares"?
  4. Re:Skizoman? by Anonymous Coward · · Score: 0

    To morons: Do NOT click on this link if you are at work.

  5. Re:Skizoman? by somersault · · Score: 1

    To everyone else: Do NOT click on this link.

    --
    which is totally what she said
  6. The study itself by mrclevesque · · Score: 1
    1. Re:The study itself by Anonymous Coward · · Score: 0

      The PositScience games are also helpful in treating dementia, brain trauma, and depression. More interesting to me, is that they also help with memory, concentration, perception, and critical thinking in normal people too.

      I used to work there, and got my copy at a discount, but I suggest anyone interested in improving (or preventing a decline in) their mental capabilities to check it out. Unlike crossword puzzles or just "keeping mentally active," the exercises were designed by leading neuroscientists, and have built-in algorithms for tuning the difficulty of the exercises to be just challenging enough to get good results.

      And no, I don't make any money if the company does well. In fact, they laid me off after 11 months and 3 weeks so I have no equity stake. So I'm a little bitter about that, but at least I can understand it clearly and articulate it well.

    2. Re:The study itself by Anonymous Coward · · Score: 0

      Link to the Demo. It makes you sign up, though.

  7. Worked for me by Anonymous Coward · · Score: 0

    The voices in my head now tell me to shoot cyberdemons until they die instead of shooting the little grey men who are watching me from behind. Watching and waiting. Waiting... waiting... waiting...

  8. Blinded by Anonymous Coward · · Score: 0

    How do you blind a study like this? What kind of control group would be fooled by a placebo (not playing actual video games)? These people would have to be crazy.

    1. Re:Blinded by Anonymous Coward · · Score: 0

      1. Think of something the researches may not have considered
      2. Not notice that this point has been addressed
      3. Raise it to prove the researches are idiots
      4. Enjoy the smug feeling of being smarter than everyone else

    2. Re:Blinded by CSMoran · · Score: 1

      Well put.

      --
      Every end has half a stick.
  9. So... about those epidemics... by Anonymous Coward · · Score: 0

    When do we start to hand out computer games to the Taliban/Al-Qaeda, Catholiban and their Israeli equivalents? In all cases including especially their spiritual leaders.

    Maybe one day, if we allow us to see religion as the schizophrenia that it is (Notice that this does not contain a judgment. Schizophrenia is not exactly a choice. Given a bad enough situation, we all may not be able to live on without falling into it.), and those people as ill and needing help. But for that, one would have to understand them.. And then we couldn't hate them and wish them death anymore based on an ignorant armchair "analysis"... just like they do with us... which apparently is acceptable if one is the $good side. :/

    P.S.: Posting anonymously only since 2009! (Because the modding system is fundamentally broken.)

    1. Re:So... about those epidemics... by derGoldstein · · Score: 3, Interesting

      I'm a firm atheist, but I don't think that the analogy to mental illness is entirely valid. Religion is more about extreme conditioning. If you have it hammered into you from an early age, in a severe manner, the mind will cling to it just as it does to physiological urges. Convincing people that theistic religion is a "delusion" only works in an environment where some freedoms are allowed -- the freedom to think for yourself, and the freedom to question anything you want to. In a fundamentalist environment, this will get you (at best) in prison.

      Many people, after spending enough time in such an extreme environment, are beyond help. They're neurologically "fused" with their beliefs.

      --
      Entomologically speaking, the spider is not a bug, it's a feature.
    2. Re:So... about those epidemics... by Anonymous Coward · · Score: 0

      Actually, IAAP (I AM a psychologist), and religion is a textbook example of schizotypy (what you'd call all the levels of schizophrenia, from the mildest to the worst states).

      Everything is conditioning. It's what Joe Random calls "learning". Same thing. So saying "it's just extreme conditioning" is nonsense. Schizophrenia also is just extreme conditioning. (To the level of having somatic effects on the brain.)
      The key difference from what you'd call "normal" learning (conditioning) is, that they turn the concept of basing your inner model of reality on the observed outside world on its head. They base their perception of reality on their inner, strongly delusional, model of "reality'.
      The reason is that reality, as it is, is not acceptable to them anymore. Either because it is too horrible. (Classical schizophrenia.) Or because it's impossible to explain for them. (Which essentially, in a more broad sense of "explain", can be said to be the inner reason for the first case too.) And this latter case is what causes religious concepts to be used as a easy cop-out fantasy world where everything is simple. "God did it."
      Also, very often the former case gets them into it, and the latter case, which they ease into, helps them keep it. (Together with avoiding processing things.)

      But you don't "convince" schizophreniacs. Ever. That's kinda the whole problem. Everything you say or do will be interpreted so that it only strengthens their inner model. What you *can* do however, is go at it through the emotional channels. They bypass the whole higher thought system and can fully override it. If something feels really good, you can't help but feel attracted to it, even If your delusional mind rejects it. (Simple test: Think about biting into a extremely sour lemon. Now you start salivating. Despite being fully aware of the fact that *there is no lemon*.)
      Which is why the most extreme religious people will usually secretly fap to a *lot* of porn. ^^
      This can be used to re-condition them to having positive associations for the irrationally rejected things.

      Because in the end, it always comes down to what feels good and what feels bad.

      About being neurologically "fused": Well yeah, that neurological plasticity declines with age, is well-known.
      On the other hand, LSD, combined with the right triggers (veery important!), is great at raising plasticity again. But don't tell anyone I told you that. ^^

  10. Re:Skizoman? by Sylak · · Score: 1

    I don't know, I think it's a valid expression of the GP's Mental Illness ;)

  11. Re:Skizoman? by Anonymous Coward · · Score: 0

    Why? It's just some vanity email service. Just the parking page. actually.

  12. Also helpful for some forms of autism and ptsd by Anonymous Coward · · Score: 0

    Some computer games have helped children with Autism and others with ADHSD (Attention Deficit Hyperactivity Spectrum Disorder). I've seen what looks like FPS (first person shooter) simulations help returning soldiers with Post Traumatic Stress Disorder, and I've also seen (a lot) of physiotherapy done with wii-fit, including modifications to wii controllers for people confined to wheelchairs who have lost muscle tone, re-gain it by ...working out by playing games. Apparently they are 'way more fun' than the crappy 'move left, move right' exercises the physiotherapists have been offering in the past. As the parent may have alluded to, there is Neuroplasticity-Based Cognitive Training going on (something I remember from university psych classes, even though I graduated as a CS major). The long and the short of it is: "Yes sparky, you really can teach old dogs new tricks", and also "be careful what you read and be careful what you learn, you're rewiring you brain at every turn". It actually is an extension of what Henry Ford claimed: "Whether you think you can't or whether you think you can, you are right."

  13. Summary is misleading. article inacurate by Jmc23 · · Score: 1
    First. this has nothing to do with treating schizophrenia. it is about treating low levels of cognitive functioning that are associated with schizophrenia.

    If using the proper probability value for such a small, and inadequate, sample there are no significant effects whatsoever.

    The cognition training given only has video-game like rewards, there is nothing video game about it. Confounding factors which they did not mention are that the test group was exposed to one type of computer training with reduced and tightly controled stimuli while the control group played 16 different computer games with lots of stimuli and played several games every day. Computer time was only 1 hour a day. Any differences in their insignificant findings could be explained by rewarding focus.

    Then again this probably just one of those papers written up to get more funding judging by their misleading use of statistics and their optimistic wording of the possible positive results if they just had more time and subjects as well as the statement that what is important is improving every day functioning and not scores on tests, n.b., both the test group and the control group showed improved daily functioning.

    I could give a more detailed analysis of how wrong this all is but this is painful enough on my N900, anybody have a laptop/tablet they're giving away? How about a motherboard for a tx2500? A job reviewing grant submissions?

    --
    Don't complain about syntax, grammar, or spelling. There is no.hell like input on android.
  14. without insurance, who gives a fuck? by decora · · Score: 1

    it doesnt matter if they cured cancer tomorrow. if it cost more than a few thousand dollars, most of the people on this planet could never afford it.

    without health insurance, all of these wonderful medical breakthroughs dont mean anything.

  15. Re:Skizoman? by Anonymous Coward · · Score: 0

    Yeah, right, and I just feel off some truck filled with turnips. Listen here you big asshole! I know who you are and I know where to find you!

  16. It's A LIE! by Anonymous Coward · · Score: 0

    Video Games can only affect people negativelly as scientists have proved and the bible says! Would someone think of the children!

  17. Sounds Like Nueurofeedback by Anonymous Coward · · Score: 0

    My neurofeedback treatments for ADHD and depression are just like video games. They work like a charm for anxiety and migraines too.