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Could a Digital Pen Change How We Diagnose Brain Function?

An anonymous reader writes: By using custom tracking software to monitor the output from a digital pen, MIT researchers say they have found a way to better predict the onset of brain conditions like Alzheimer's and Parkinson's. according to MIT: "For several decades, doctors have screened for conditions including Parkinson's and Alzheimer's with the CDT, which asks subjects to draw an analog clock-face showing a specified time, and to copy a pre-drawn clock. But the test has limitations, because its benchmarks rely on doctors' subjective judgments, such as determining whether a clock circle has 'only minor distortion.' CSAIL researchers were particularly struck by the fact that CDT analysis was typically based on the person's final drawing rather than on the process as a whole. Enter the Anoto Live Pen, a digitizing ballpoint pen that measures its position on the paper upwards of 80 times a second, using a camera built into the pen. The pen provides data that are far more precise than can be measured on an ordinary drawing, and captures timing information that allows the system to analyze each and every one of a subject's movements and hesitations."

23 comments

  1. Not unless... by bazmail · · Score: 0

    ...there is some sort of diagnostic machine attached to it and it can actually extract some sort of medical info from the brain. I'm not a doctor though.

    1. Re:Not unless... by Anonymous Coward · · Score: 1

      You're not a doctor and your comment is rather inane and useless. Do you ever read summaries here? Did your working memory fail to remember the beginning of the first sentence after the title "By using custom tracking software to monitor "... Let's skip all that... Is someone going to design a brain scanning pen with no means to read any of the data? Really? I don't bother to read summaries either sometimes, but I sure as shit know what's gonna come next from me is a curse or moronic shit post. You seem unaware. Here's me helping you on that. You're welcome.

    2. Re:Not unless... by bazmail · · Score: 0

      You're touchy. We should totally hang out.

    3. Re:Not unless... by Anonymous Coward · · Score: 0

      I must admit: you got owned by that AC.

  2. Hesitation means you're crazy!! by Anonymous Coward · · Score: 0

    But what if I'm terrified of making a mistake? If I work slowly and haltingly then either I have a brain condition or I lack confidence.......but either way I'm a loser and no one will ever talk to me again!! Holy shit I'm fucking screwed!!!!

  3. article with question in the title? by umghhh · · Score: 1
    I thought there were a meme for that?
    I have to objections to the bod statements from the summary and TFA.
    Firstly the subjective judgment of the pictures of clocks etc made by patients is indeed subjective if done by a human. So far so good. But then I know from my own painful experience that my drawing skills have been showing Parkinson in grand school already. My drawings and those of other kids in the class showed a massive difference similar to that in TFA. It changed drastically after I attended technical drawing course (then technical drawing was done by hand!). I see almost the same with my oldest kid. So judging on pictures made by patients is good but comparing those to whatever external norm has to be calibrated for the person. This problem seems to be addressed more easily by humans than machines. It may change if the comparison is done over time to own pictures of the same object I guess.
    The second objection is formal - if we either way judge on the quality of picture made by a patient then the actual diagnostic method does not change only the tool used does thus making it big flat 'NO' as an asnwer.

    Maybe I see it wrong but the answer to the question in summary and TFA is NO even if new method is diagnostically better than the old one (which it may or not be). Good to know tho - if I see that my drawings go back to old times I will know problems ahead. If this is early stage I will still be able to do the right thing then if so I wish.

    1. Re: article with question in the title? by Anonymous Coward · · Score: 1

      At least they are are collecting real data rather than just one subjective score.

    2. Re:article with question in the title? by Anonymous Coward · · Score: 0

      I'm no medical expert, but I'm sure that this test - either performed by an actual human, or an algorithm - is used in screening and early detection, and in no way substitute for other diagnostic tools. TFA seems to suggest to me that they want to make them more objective by replacing the human element in analyzing the drawings.

    3. Re:article with question in the title? by Anonymous Coward · · Score: 1

      The key here is to monitor how you're actually handling the pen. Your ability to draw a clock is nothing but a proxy for measuring your motor control. Just having an accelerometer that tracks how much twitching you do would allow you to detect those spasms even if the patient stops drawing for a second while waiting for the shakes to pass.

    4. Re:article with question in the title? by Anonymous Coward · · Score: 0

      Are "to objections" more than two objections? Or less?

      That must have been one helluva grand school that taught you how to count like that!

  4. YES! by Anonymous Coward · · Score: 0

    Wait.

    NO!

    Did I get it right?

  5. What is a pen? by Blaskowicz · · Score: 2

    Isn't that technology for terrorists and luddites? Writing on non-monitor surfaces ought to be banned. We need to send everything to Microsoft ; arguably we can put in a system with that high tech pen which denies inking before proprer Internet connection and authentication are established, and then the camera can film what's written. So that's good, but the pen may leave a series of words that can then be read unsupervised. So I'm on the fence whether this should be allowed or not, probably some form of paper management should exist and/or just put those that can access the paper under "closer surveillance".

    1. Re:What is a pen? by amalcolm · · Score: 1

      1984 called - they want their paranoia back :)

      --
      Time for bed, said Zebedee - boing
    2. Re:What is a pen? by Anonymous Coward · · Score: 0

      See, I was gonna go with "Do kids even know what a pen is nowadays?" But yours is better.

    3. Re:What is a pen? by sjames · · Score: 1

      That was more persuasive before we proved that the NSA was spying on everyone with the help of their corporate friends.

  6. hmm by Blymie · · Score: 1

    While I would not draw a clock as per the example image, I've always been *crappy beyond belief* at drawing circles, you name it. Hell, my hand writing makes chicken scratch look like fine art.

    For the circle, I'd get the numbers in the approximate correct place, you know, put 9 and 3 and 12 and 6 in first -- but, I can imagine people that never really drew much, perhaps not even thinking about that ahead of time.

    So yeah, my circle might be as misshapen as the one in the example article. And, someone that is poor at makin' a circle as me, but has also never thought of the clock-draw, pre-set your numbers concept -- may do just as the example did.

    My point is that the pen is an excellent idea, but the doctor's subjective opinion is a detractor AND an benefit. The pen will get rid of both sides of the equation. I'm not sure how accurate it will be, and it may be more of a 'this is a cool product!" that isn't wanted or needed.

    (I'm willing to bet that if you ask many doctors, they'll say "My educated, well informed opinion on test outcome is a benefit, not a detractor!")

    1. Re:hmm by Anonymous Coward · · Score: 0

      While I would not draw a clock as per the example image, I've always been *crappy beyond belief* at drawing circles, you name it. Hell, my hand writing makes chicken scratch look like fine art.

      You quite elderly but not so very ancient person are from a generation of people who actually used a pen during at least some part of their life. As diagnosed issues are typically in people of significant age, they have used pens even more than you did. Looking at the next generation, the complete test becomes meaningless, because no-one will be able to even hold a pen anymore. Using some trained ability as indicator doesn't make any sense whatsoever.

      A skill-check always requires a personal baseline.

    2. Re:hmm by Anonymous Coward · · Score: 0

      The next generation will be tested on their ability to plug microusb cables into their respective ports.

  7. nice by evolutiadan · · Score: 1

    nice

    --
    Evolutiadan Echipamente zootehnice si produse ferma
  8. maybe could also diagnose by __aabppq7737 · · Score: 1

    Tourettes syndrome

  9. meanwhile, back in the real world by Anonymous Coward · · Score: 0

    is it cheaper (cause, ya know, healthcare cost money)
    does it help the patient ?
    does it help the doctor make a decision about what to do ?

    no
    no
    no

    just hyped tech