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FDA Approves Drug That Uses Herpes Virus To Fight Cancer (nature.com)
An anonymous reader writes: U.S. regulators have approved a first-of-a-kind drug that uses the herpes virus to infiltrate and destroy melanoma. Nature reports: "With dozens of ongoing clinical trials of similar 'oncolytic' viruses, researchers hope that the approval will generate the enthusiasm and cash needed to spur further development of the approach. 'The era of the oncolytic virus is probably here,' says Stephen Russell, a cancer researcher and haematologist at the Mayo Clinic in Rochester, Minnesota. 'I expect to see a great deal happening over the next few years.' Many viruses preferentially infect cancer cells. Malignancy can suppress normal antiviral responses, and sometimes the mutations that drive tumour growth also make cells more susceptible to infection. Viral infection can thus ravage a tumour while leaving abutting healthy cells untouched, says Brad Thompson, president of the pharmaceutical-development firm Oncolytics Biotech in Calgary, Canada."
I used LSD and marijuana to cure my alcoholism.
Nice. How novel is that? As ugly as a cold sore is, how preferential it might be to eminent death...
Happiness in intelligent people is the rarest thing I know.
Ernest Hemingway
mutations that drive tumour growth also make cells more susceptible to infection
Interesting. Like cave dwelling creatures who've "lost" (by process of evolution) their sense of sight in order to enhance other senses. It's all good until some other creature invents a flashlight.
Yes, we are a step closer to I Am Legend.
Herpes virus used to cure cancer, the premise of that Will Smith zombie movie awhile back.
Nice! Fuck Marijuana! We got Herpes sinplex 10. Here. Rub this on your face. Oooooo, yeah, just like that.
Nice. How novel is that? As ugly as a cold sore is, how preferential it might be to eminent death...
I dunno... it might be a close call if I could get an eminent death out of it.
Fight Cancer.
Get Herpes!
Not an even exchange.
Sorry.
They'll never get cancer!
Around 1981 I managed to catch herpes from some equally drunken young lady and suffered for about 2 weeks without ever having any subsequent outbreaks. Does that mean I'm equally immune to this as a treatment?
It's not like that! I got cured from cancer!
What if we already had an effective herpes vaccine? Wouldn't this treatment be ineffective in the immunized portion of the population?
I first posted this 13 years ago. Sad how long it takes http://m.slashdot.org/story/40...
So like Legend but bad (distasteful sores)...
sweet, I'll never get cancer!
I think you'll find it isn't that Viruses preferentially infect cancer cells, its that by definition, a cancel cell grows fast than a non-cancer cell.
And since Viruses piggy back onto the cell reproduction, then they get the faster growth too. So of course they would attack cancer cells more, because the cancer cells have a faster reproduction, so they make more viruses.
What does it cost, roughly, too get this kind of Slashvertisment?
Do you pay them straight out cash, or is it more of a hookers and blow thing?
https://www.youtube.com/watch?v=rLcXvgv4FYI
https://www.youtube.com/watch?v=Dzs-09Of99I
From here.
http://it.slashdot.org/comments.pl?sid=8241145&cid=50822911
Please!? Come on, medical researchers, if you're playing around with the goddamned herpes virus, could you please cure it while you're at it!? Please!?
introducing one species to control or eliminate another......
You sound like a fat person trying to defend your disgusting looks, smell and lifestyle.
What if, just what if the rare "miracle cure" from cancer have been an exotic viral infection in some far away place? It was not the giving your little money to the foreign priest that just arrived and promised a miracle cure if you only believe, but that visit to the local cave with bats and spiders.
"FDA Approves Drug That Uses Herpes Virus To Fight Cancer"
I have to admit, I feel somewhat conflicted about this.
And what about people who already have herpes, can they get a discount?
Disclaimer: I lived through the 1970's and didn't get herpes, a fact that I'm rather proud of considering all of the sleazy girls I banged during that decade. Luck of the draw, I guess.
Just cruising through this digital world at 33 1/3 rpm...
I suspect the tumors will just add the viruses uniqueness to its own.
What a great movie. The late great Robert Urich. https://www.youtube.com/watch?...
This is so cool! I work just down the hall from Dr. Kaufman at CINJ. His lab is one of the labs developing these herpes virus cancer therapies. My lab uses vaccinia, the smallpox vaccine virus, doing similar research (I'm also working on a melanoma model). We use GM-CSF just like this one, but also add in some tumor-specific antigens to increase targeting to the tumors. It's quite exciting stuff, and we even had a promising clinical trial against pancreatic cancer recently.
Enjoy post-apocalyptic and singularity science fiction? Check out www.demonarchives.com, a new online graphic-novel.
It would be interesting if the discount plan for administering this cure was to sleep with your doctor. (Doesn't hurt that my doctor is the opposite gender as I, and definitely not unattractive)
Just think, they could rename brothels to be "treatment centers".
I have experience with that as my father was diagnosed with stage IV colorectal cancer and his chemotherapy is killing him faster than his cancer. Here is an email I sent to his oncologist, demanding he be taken off of chemo with the evidence I gathered that chemo was a bigger threat than his cancer currently. The oncologist only responded by cutting off contact.
The email:
I have been talking to my father. He has been experiencing a loss of appetite, a side effect shared by Avastation[1], Oxaliplatin[2] and 5-Fu[3] which he is receiving. Today he ate just some yogurt and a half cup of soup all day. He also has difficulty swallowing[1], and is experiencing taste changes[3]. He has a low white blood cell count[3], which means his immune system is also comprised thanks to chemo[4]. When eating certain foods like bread he has nausea[1, 2, 3]. Cancer is a wasting disease, even without chemo patients have difficulty maintaining bodyweight. The chemo you are giving him is making it even harder for him to maintain bodyweight. My uncle says he looks like a starving African.
According to the published journal literature, in contributing positively to 5 year survival, chemotherapy, is only effective in less than 3% of cases[5]. More specific research to the type of cancer my father has reveals: "stage II colon cancer patients who received chemotherapy treatment were more likely to have poor [quality of life], recurrence, and all-cause mortality after 24 months compared to those who did not receive chemotherapy."[6] A study on the use of chemo in end stage cancer, since my father is in Stage IV, maintains in its conclusion: "The [quality of life near death] in patients with end-stage cancer is not improved, and can be harmed, by chemotherapy use near death, even in patients with good performance status."[7]
In the Family Leave Form you kindly filled out(which I do appreciate) for my employer you stated that one of the reasons my father needed care was, "Terminal stage colorectal cancer with cognitive failure." According to the research again, while cognitive impairment is present in many cancer patients before treatment, chemo is known to increase the incidence of impairment[8]. In another field you entered: "He [sic] hospitalized 3 times due to toxicity secondary to treatment," which I read as him being hospitalized because he received chemo, not because he has cancer.
I would appreciate it for all these reasons if effective immediately you cease administering chemotherapy to my father, who you noted has "cognitive failure" and is under the mistaken impression he has a benign tumor and will live indefinitely, so that he can enjoy some measure of a quality of life in his last days and months alive. If it is required when I arrive in Greece, I will have to tell him the truth and explain to him his real prognosis and how chemo is at this point a bigger threat than his cancer, but I don't want to drop this bomb over the phone and into my uncle's lap who himself is not well and has multiple sclerosis.
I am not attacking you in a professional capacity, because this is basically what I expect from every doctor and which is why I avoid doctors. I am sure oncologists in the USA are just as in love in with ineffective chemotherapy and just as forbidden from doing anything else. I would appreciate it if I can receive pathology, MRI Scan and surgical reports(if any), two blood tests (CBC,SMA-24) no older than two weeks on my father so I can take him abroad for 2-3 weeks somewhere(not the USA as our cancer care is just as chemo centered) so he can gain some bodyweight, improve his white blood count(immune system) and generally get healthier, instead of focusing exclusively on killing his cancer with chemo to the point that he obviously currently has a very low quality of life, since it cannot discriminate between healthy and cancer cells.
[1] http://www.drugs.com/sfx/avastin-side-effects.html
[2]
With all the pussy I get, I picked a few things along the way. But at least I won't get cancer!
Found it! https://youtu.be/AF3YU4lIpEc?t...
They're biting off my style from long ago
"Imitation is the sincerest form of flattery - mere paper roses"
Arrogance of the highest order purveyed by the most delusional visitor to slash dot since michael kristopeit. Nobody gives a shit what you think you invented asshole.
"Nobody gives a shit" - by Anonymous Coward on Thursday October 29, 2015 @09:54PM (#50830169)
A projecting reply from your primitive brain gives it away & a sampling of /.'ers contrary opinions outnumbering you:
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"his hosts program is actually pretty good" - by xenotransplant (4179011) on Monday August 10, 2015 @03:34PM (#50287195)
"I like your host file system." - by Karmashock (2415832) on Wednesday September 09, 2015 @03:57PM (#50489401)
"APK is kinda right... I've given up on JS based adblocking and gone to blackholing in /etc/hosts, just like it was back in the 90s. The computational load has gotten intolerable for any ad-blocking using JS. I've tried his hosts file generating software. It works." - by bmo (77928) on Thursday October 15, 2015 @11:30AM (#50736071)
"his hosts tool is actually useful for those cases in which one does indeed want to locally block stuff outright while consuming minimum system resources" by alexgieg (948359) on Friday September 25, 2015 @09:57AM (#50596461)
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* So, what's that YOU said again quoted above & below after "EATING YOUR WORDS" troll?
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"Arrogance of the highest order purveyed by the most delusional visitor to slash dot" - by Anonymous Coward on Thursday October 29, 2015 @09:54PM (#50830169)
You've delusions of grandeur you're a psychiatric pro, lmao!
I'm somebody and somebody who does others right.
You're just cowardly unidentifiable scum and you KNOW it. It's why you hide by unidentifiable ac posts + why you're an unimaginative unskilled douche nobody in computing!
Above all else:
IT'S NOT POLITE TO TALK WITH YOUR MOUTH FULL & YOURS IS - full of your FOOT IN YOUR MOUTH ramming down those WORDS OF YOURS YOU MUST EAT washed down w/ the "bitter taste of SELF-defeat" (the story of your wasted low life... lol!)
APK
P.S.=> YOU fail vs. my SUPERIOR factual firepower vs. your (lol) "ne'er-do-well'ism" (for lack of a better description - It's hard for the likes of me to comprehend wastes of life like you)... apk
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