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First Human Eggs Grown In Laboratory (bbc.com)

An anonymous reader quotes a report from the BBC: Human eggs have been grown in the laboratory for the first time, say researchers at the University of Edinburgh. The team say the technique could lead to new ways of preserving the fertility of children having cancer treatment. It is also an opportunity to explore how human eggs develop, much of which remains a mystery to science. Experts said it was an exciting breakthrough, but more work was needed before it could be used clinically. Women are born with immature eggs in their ovaries that can develop fully only after puberty. It has taken decades of work, but scientists can now grow eggs to maturity outside of the ovary. It requires carefully controlling laboratory conditions including oxygen levels, hormones, proteins that simulate growth and the medium in which the eggs are cultured. But while the scientists have shown it is possible, the approach published in the journal Molecular Human Reproduction still needs refinement. In the paper, the researchers describe "how they took ovarian tissue from 10 women in their late twenties and thirties and, over four steps involving different cocktails of nutrients, encouraged the eggs to develop from their earliest form to maturity," reports The Guardian. "Of the 48 eggs that reached the penultimate step of the process, nine reached full maturity."

43 comments

  1. LOOKING FORWARD 2 FIRST HUMAN OMELETTE by Anonymous Coward · · Score: 0, Funny

      mexican style

    1. Re:LOOKING FORWARD 2 FIRST HUMAN OMELETTE by mnemotronic · · Score: 1

      mexican style

      Whoa. Requesting that omelette made with eggbeaters or "whites only" takes on a whole new meaning, don't it?

      --
      The Russians have won. They have made the world a cesspool of distrust, greed, fear and hate.
  2. Silly by Anonymous Coward · · Score: 4, Funny

    Humans don't lay eggs. They're mammals.

    1. Re:Silly by Hognoxious · · Score: 1

      I'm an echidna, you insensitive clod!

      --
      Confucius say, "Find worm in apple - bad. Find half a worm - worse."
    2. Re:Silly by MerlTurkin · · Score: 1

      That's what I been trying to tell them! And what, no bacon?

  3. Troll posts by TheReaperD · · Score: 1, Interesting

    What the hell is up with all the idiotic troll posts on this article? Who moved the rock?

    --
    "Be particularly skeptical when presented with evidence confirming what you already believe." -
    1. Re: Troll posts by Anonymous Coward · · Score: 0

      It's saturation bombing to make sure all on topic -1 posts, i.e. opinions the article sponsor does not want to see discussed, are not seen as they go under in all the chaff.

  4. Why? by Anonymous Coward · · Score: 0

    Are we running out of people?

    1. Re:Why? by DivineKnight · · Score: 1

      We are running out of the right kind of people. People willing to work for next to nothing, for long hours, doing pointless tasks.

      You can thank the Internet for that.

    2. Re:Why? by arth1 · · Score: 1

      Some people have a very strong desire for having children, to the point that this urge rules their lives. I think a better solution is to offer psychiatric medicine to help people overcome this compulsion.
      If you have genes that make you susceptible to either dying or becoming sterile before mating age, those genes do not need to be rewarded. It's not like anyone dies if you don't have children, but a future grandchild may very well die because you chose to have children despite known problems.

    3. Re:Why? by dgatwood · · Score: 1

      If you have genes that make you susceptible to either dying or becoming sterile before mating age, those genes do not need to be rewarded. It's not like anyone dies if you don't have children, but a future grandchild may very well die because you chose to have children despite known problems.

      There are three problems with that logic:

      • Most childhood cancers aren't caused by genetic defects. (Well, to be pedantic, they are caused by damaged genes, but not heritable genetic defects.)
      • Even for heritable genetic defects, there is also a possibility that the defect, in conjunction with some other combination of genes, A. will not cause the same harm, and B. might confer some unexpected advantage for the survival of the species.
      • There's a pretty good chance that by the time it causes problems for your grandchildren, we'll be using CRISPR or whatever to rewrite the defective genes, and it won't matter that you passed the bad genes on.
      --

      Check out my sci-fi/humor trilogy at PatriotsBooks.

    4. Re:Why? by Anonymous Coward · · Score: 0

      Never mind the internet. We (=they) will grow humans in the lab, the right kind.

      And btw, the last thing "children having cancer treatment" care about is "preserving the(ir) fertility".

    5. Re: Why? by Anonymous Coward · · Score: 0

      That's pretty much what the latest developments are leading up to, the deliberate alienation of the sexes, the war against family, the disconnection of sex from reproduction, abortion and now these wonderful new technologies all leading to test tube clone babies that leave the hatcheries ready for their initial behavioral conditioning, then their common core education and then whatever training applicable to the specialty they have been optimized for. The new world is now.

    6. Re: Why? by umghhh · · Score: 1

      The new world is always today and changes are difficult especially if you are not in control of them. There will be new species anyway. Or something looking like it never mind resistance of some. I may not like it but I would not mind extension of my brain into silicon (if it worked of course) or whatever else scientists come up with as an extending substance. There are many hoping this will bring us to new heights. The result will be that maybe but for sure new ways we will be sucked dry by owners of this planet. Some may live in an illusion of a harmony and implementation of the new devices for good of everybody and the community till they look beyond the fence. There are so many humans. Why worry?

    7. Re:Why? by MerlTurkin · · Score: 1

      I wish!

  5. As long as we remember THIS day... by Hallux-F-Sinister · · Score: 2

    We will always know, definitively, in the future, for OUR species, at least... which came first: it was the human, and not the egg. ;-)

    --
    Our reign has gone on long enough. Indeed. Summon the meteors.
    1. Re:As long as we remember THIS day... by PolygamousRanchKid+ · · Score: 1

      which came first: it was the human, and not the egg. ;-)

      Now we just need to grow some human bacon in the lab and then we will be all set for breakfast.

      --
      Schroedinger's Brexit: The UK is both in and out of the EU at the same time!
    2. Re:As long as we remember THIS day... by Anonymous Coward · · Score: 0

      What, no human toast?

      Philistine!

    3. Re:As long as we remember THIS day... by mentil · · Score: 1

      Don't forget the tall frosty glass of human milk.

      --
      Corruption is convincing someone that the selfless ideal is the same as their selfish ideal.
    4. Re:As long as we remember THIS day... by Anonymous Coward · · Score: 0

      Actually it can be argued that the human is the egg's way to procreate.

  6. But it still requires ovaries. by dgatwood · · Score: 4, Interesting

    That's pretty cool. The one unfortunate thing is that it still requires you to start out with viable eggs, albeit undeveloped viable eggs, which won't help anyone who has already undergone those sorts of medical treatments.

    On the other hand, when we eventually do manage to grow eggs from normal cells, the medical ethics questions will get pretty crazy:

    • Should there be an upper age limit to prevent high rates of genetic defects?
    • Should it be illegal to create a baby with an unknowing girl by stealing a strand of her hair?
    • When it eventually happens anyway, what legal rights will the child have?
    • If you are asked to construct eggs from XY cells from someone who has undergone a gender change, are you ethically required to tell her husband?
    • When shaking the hand of your date, is it appropriate to wear a glove to prevent conception?

    And so on.

    As is often the case, I can't entirely tell if I'm joking or being serious with this comment. Moderate appropriately. :-D

    --

    Check out my sci-fi/humor trilogy at PatriotsBooks.

    1. Re:But it still requires ovaries. by Betty+Crocker · · Score: 1

      Please don't be a sexist. Those days are over.

    2. Re:But it still requires ovaries. by Anonymous Coward · · Score: 0

      It'd be nice if that was actually true.

    3. Re:But it still requires ovaries. by Kjella · · Score: 1

      When it eventually happens anyway, what legal rights will the child have?

      This one pretty settled already, doesn't matter if you got a blowjob or even if she found a used tissue... your DNA, your kid. It's more interesting how it plays into one of sci-fi's big themes about growing humans in a lab though. They're making progress on a artificial uterus, my guess is that sometime this century we'll be able to take undeveloped eggs, bring the eggs to maturity, fertilize them and grow babies in a tank. Let the clone wars begin...

      --
      Live today, because you never know what tomorrow brings
    4. Re:But it still requires ovaries. by dgatwood · · Score: 1

      They're making progress on a artificial uterus ...

      This one, I've been looking forward to for at least a decade, because it means we'll finally be able to put the abortion debate to rest once and for all. Victim of rape? Incest? At risk of death from pregnancy? No problem. We'll just transplant the fetus (intravaginally or by caesarean) into an artificial womb, and now the child has a right to life and the mother has a right to choose, all at the same time. No more false dichotomy promulgated by tyrants in their lust for power.

      The real question is what the Republican party will do to hold onto the Christian vote once they lose abortion. After all, their positions on the death penalty, helping the poor, etc. won't do them any favors. Maybe, just maybe the Republican party will completely implode, and we'll end up with a choice between Democrats and Libertarians, along the other political axis this time. I'm not sure that will be a good set of choices, either, but it can't get much worse than the options we have now.

      --

      Check out my sci-fi/humor trilogy at PatriotsBooks.

    5. Re:But it still requires ovaries. by rtb61 · · Score: 2

      Actually totally incorrect. You start out as a viable egg, women start out as a viable egg. Up comes mr sperm and it is consumed and it's genetic resource is strip mined to trigger further grow. So women start with zero eggs and then the DNA process triggers the creation of the egg creation structure and juvenile eggs are made. Likely egg production and cancer have some core similarities, that growth from something else. A none egg cell, turning into an immature egg cell and growing from there. As for the other stuff, the human individual with society has inalienable rights, it is a question of when they start and the problem is for women failing to get pregnant of course men masturbating. As soon as they are viable seems to be the defining moment and not too much before that. Either that it make it illegal for men's sperm to die outside of a women's vagina, apart from proven accidental discharge but that is bizzaro world stuff.

      --
      Chaos - everything, everywhere, everywhen
  7. eggs by Anonymous Coward · · Score: 0

    In the year 2525, if man is still alive...if woman can survive....

    1. Re:eggs by Anonymous Coward · · Score: 0

      Ahh, those nostalgic feelings...

  8. Artificial Gametes by mentil · · Score: 1

    Combine with this research and we'll soon have children made from artificial gametes. Now all we need are artificial wombs. Hey, what's a high-tech country whose women are too busy with their careers to go on maternity leave? Japan's a good bet for this. I would wonder if artificially-conceived children would violate China's one-child rule, but that was repealed already.

    --
    Corruption is convincing someone that the selfless ideal is the same as their selfish ideal.
  9. Minecraft becoming reality by grungeman · · Score: 2

    Me (watching 6 year old son play Minecraft): Who are all those people running around?
    Son: Those are villagers.
    Me: And where do they come from?
    Son: Why, of course from eggs!

    --

    Signature deleted by lameness filter.
  10. We already have artificial wombs by wisebabo · · Score: 1

    https://www.theverge.com/2017/...

    Granted it hasn't been tested on humans (not that we know of, maybe in China?) but it's only a matter of time. I'm sure there will be a market from celebrity women not willing to lose their figure over pregnancy and not wanting to go through the hassle of surrogacy.

    So is it now feasible to talk about colonizing other worlds without having (living) humans going there? Send a spacecraft capable of creating it's own eggs (and having frozen sperm which I believe are easier to keep) and have the embryos develop and come to term in the artificial wombs. Decant them and have them raised by A.I. robots. If you're worried about genetic damage from long term exposure to cosmic rays made worse by high speed interstellar travel, consider creating the human genome from scratch (the Human Genome Write project started a year or two ago).

    I think there were a number of science fiction stories that used this device to propagate the species over vast distances. In one, I believe the new humans eventually managed to create a self-sustaining colony but there were significant problems in organizing a society at first because of the psychological damage from having non-human parents. Anyway, in a last ditch save the species plan, it would allow for a much smaller number (zero?) of female astronauts to provide the necessary services.

    1. Re:We already have artificial wombs by mentil · · Score: 1

      Interesting, but a mother is still required up to the point where its blood vessels can be connected to the bag's umbilical.
      Those lamb bags make me think of sous vide... the comic almost writes itself.

      --
      Corruption is convincing someone that the selfless ideal is the same as their selfish ideal.