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Final Results of NASA Twins Study Show How Scott Kelly Changed After a Year In Space (gizmodo.com)
The final findings of the NASA Twins Study, which compared 50-year-old astronaut Scott Kelly, who spent a year aboard the International Space Station in 2015, and his identical twin brother, who stayed on Earth, were published in Science. Gizmodo reports: NASA found that Scott Kelly was about as mentally, physically, and genetically healthy as his brother during his trip to space, and that the vast majority of small changes spotted in Scott (relative to himself before the mission) went back to normal within six months time. But the differences seen in Scott while up in space and after his return home could provide NASA important leads on how to keep astronauts safe during longer missions to Mars and beyond.
Preliminary results from the study were released in 2017. But it was the second round of findings, released in January 2018, that really caught the attention of media outlets, some of which misrepresented what was found. In particular, outlets like Newsweek reported that a whopping "seven percent of [Scott Kelly's] genes did not return to normal after he landed." Others implied that Scott Kelly had become a different person from his twin brother. But the researchers were never talking about a seven percent difference between the twins' genes. They were saying that some of Scott Kelly's genes had changed in their expression -- the carrying out of instructions in a cell's genome -- during his time up in space. And that roughly 7 percent of this overall change in gene expression could still be seen six months after he returned home. The remaining change in gene expression six months out was actually closer to 10 percent, but NASA clarified that this was still a relatively tiny change in his epigenetics. "Given that the majority of the biological and human health variables remained stable, or returned to baseline, these data suggest that human health can be mostly sustained over this duration of spaceflight," said NASA in a statement.
Preliminary results from the study were released in 2017. But it was the second round of findings, released in January 2018, that really caught the attention of media outlets, some of which misrepresented what was found. In particular, outlets like Newsweek reported that a whopping "seven percent of [Scott Kelly's] genes did not return to normal after he landed." Others implied that Scott Kelly had become a different person from his twin brother. But the researchers were never talking about a seven percent difference between the twins' genes. They were saying that some of Scott Kelly's genes had changed in their expression -- the carrying out of instructions in a cell's genome -- during his time up in space. And that roughly 7 percent of this overall change in gene expression could still be seen six months after he returned home. The remaining change in gene expression six months out was actually closer to 10 percent, but NASA clarified that this was still a relatively tiny change in his epigenetics. "Given that the majority of the biological and human health variables remained stable, or returned to baseline, these data suggest that human health can be mostly sustained over this duration of spaceflight," said NASA in a statement.
Why are we only just doing this now? There's so much still to learn and yet here we are, living in the future and we're stuck here wondering what a lousy year in orbit does with a control sample. Get your goddamn act together, humanity, for fucks sake we need to leave before we finish destroying this place and rendering it uninhabitable.
"... these data suggest that human health can be mostly sustained..."
That description sounds so familiar...
(Ford Prefect expands entry for Earth in the Guide)
Ah, yes. No wonder my confidence level is still a bit low regarding intergalactic travel.
If 10% of genes show different expression levels from his twin brother, that's pretty much meaningless from a biological standpoint. Sitting vs standing will alter expression levels, eating vs fasting. The differing levels here (according to the report) include both those created by natural variation and those attributed to space-time (which would also include things like extended sitting vs standing or however the body treats long-term weightlessness). Twins aren't perfect copies of each other, they are still affected by life just like everyone else; stress, physical fitness, eating habits, infections, and all the rest, will still affect them and create differences. A persistent infection (something slow and lowkey, such as HPV16) could easily cause a longterm difference in gene expression as immune-response related genes would continuously need to be expressed.
We all have natural variation in gene expression. Compare yourself to your sibling and you will find it. Some of it comes from genetic variance (mutations or extra copies of genes either inherited from your parents or developed as you are exposed to things like sunlight, viruses, radiation etc), some of it comes from epigenetic variance (what you eat, what you put in your bloodstream, stress levels, exposure to unpleasant things, viruses, etc), and some of it comes from royally fudged gene regulation (when either of the two earlier factors localizes in the "anchor" sites of the DNA which will affect a large cluster of genes in interesting ways).
In short, no one is turning into a mutant, no one is getting any super powers.
So according to newspapers Lamarck rules in space? That would be his final revenge.
Newsweek went out of business a few years back and a scummy publisher bought the rights to the name "Newsweek" and started publishing "news" more appropriate to the Weekly World News. It's no longer a weekly source of high-class journalism. It's now a daily source of sensationalism and throw-away click-bait articles.
... in this low earth orbit and behind this space station shielding.
"7% change in Genes, that is like: His is still a mammal, Right?"
Humans will never live on another planet on a permanent basis. We will never even live on the moon on a permanent basis. Space is so big that we can travel for so long that every one of your ancestors could live and die again and we will not reach another solar system.
Astronaut Scott Kelly was bold enough to strap himself into a rocket, take a ride into space and stay on the ISS for a year....
But after he came back, he lacked the fortitude to tell some angry cranks to go pound sand when they got upset that he quoted Winston Churchill. He even bowed and scraped trying to get back in their good graces. That's some significant deterioration that may have been outside the scope of NASA's health research.
https://www.washingtonexaminer...
Alcohol, Tobacco and Firearms should be the name of a store, not a government agency.
Little weird though that he came back and married his grand-niece.
As I have yet to read much up on this, yet, are these affects solely due to the lack of gravity exhibited on the body?
If the same experiment were performed, yet the whole year in space was in a centrifuge supplementing artificial gravity, would we still see the same outcome?
I'd really like to know if that alone, limits quit a bit of the alterations being seen on the body from this outcome.
âoeOthers implied that Scott Kelly had become a different person from his twin brother.â
How ridiculous. /s
Pretty sure Nasa found that space does cause some heart disease.
They think it is radiation.
We can't trust Newsweek ... ?!
Next they're going to be telling me that the Washington Post is a questionable news source or that Hillary might lose the 2016 election !
...because his wife got pregnant while he was in space.
He BECAME A POLITICIAN ! Clearly this needs to be looked into for some sort of cure.