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Researchers Develop AI To Predict Hospital Readmission Rates From Clinical Notes

Researchers at New York University and Princeton have developed a framework that evaluates clinical notes and autonomously assigns a risk score indicating whether patients will be readmitted within 30 days. They claim that the code and model parameters, which are publicly available on Github, handily outperform baselines. VentureBeat reports: As the researchers point out in a preprint paper on Arxiv.org, clinical notes use abbreviations and jargon, and they're often lengthy, which poses an AI system design challenge. To overcome it, they used a natural language processing method -- Google's bidirectional encoder representations from transformers, or BERT -- that captures interactions between distant words in sentences by incorporating global, long-range information. Each clinical note is represented as a collection of tokens, or subword units extracted from text in a preprocessing step. From multiple sequences of these, ClinicalBERT identifies which tokens are associated with which sequence. It also learns the position of tokens from variables corresponding to the sequences, and inserts a special token used in classification tasks in front of every sequence.

To train ClinicalBERT, the team sourced a corpus of clinical notes and masked 15 percent of the input tokens, forcing the model to predict the concealed tokens and whether any two given two sentences were in consecutive order. Then, drawing on the Multiparameter Intelligent Monitoring in Intensive Care (MIMIC-III), an electronic health records data set comprising over two million notes from 58,976 hospital admissions of 38,597 patients, the researchers fine-tuned the system for clinical forecasting tasks. Tested on a sample set consisting of 30 pairs of medical terms designed to assess medical term similarity, the authors report, ClinicalBERT achieved a high correlation score, indicating that its tokens captured similarity between medical concepts terms. Heart-related concepts like myocardial infarction, atrial fibrillation, and myocardium were close together, they say, and renal failure and kidney failure were also close.

29 comments

  1. Awesome by bmimatt · · Score: 1

    Cue in greedy insurance companies digesting that data and kicking off their 'ai' designed to ramp up premiums. Excellent.

    1. Re:Awesome by Anonymous Coward · · Score: 0

      Yaaaay! Let's write a program in VBScript and call it Al. Yay we so smart!

    2. Re:Awesome by Humbubba · · Score: 1
      This story is about saving the healthcare industry money. But I think AI could help the patient too, by predicting which doctors will have more patients readmitted within 30 days.

      And just maybe, with a richer database, based on the patient's latest exam(s) and previous history, as found in their recorded electronic health records, AI might outperform doctors with better diagnoses, recommended prescriptions, rehabilitative care, etc.

      Not that I'm saying AI should do the exam itself. Having AI administer any kind of health care in any kind of way definitely needs professional human oversight. At least for now.

  2. doctor handwriting ocr with an 95+ rate? by Joe_Dragon · · Score: 2

    doctor handwriting ocr with an 95+ rate?

    1. Re:doctor handwriting ocr with an 95+ rate? by gweihir · · Score: 1

      Don't think that is possible. This is based on electronic records.

      --
      Most ACs are not even worth the keystrokes to insult them. Be generically insulted by this and ignored otherwise.
  3. virtual doctor says "You get leprosy good bye" by Joe_Dragon · · Score: 1

    virtual doctor says "You get leprosy good bye"
    https://www.youtube.com/watch?...

    1. Re: virtual doctor says "You get leprosy good bye" by Anonymous Coward · · Score: 0

      Heart-related concepts like myocardial infarction, atrial fibrillation, and myocardium were close together, they say, and renal failure and kidney failure were also close.

      When did AI get so smart?

  4. Re:virtual doctor says "You got leprosy good bye" by Joe_Dragon · · Score: 1

    Re:virtual doctor says "You got leprosy good bye"

  5. NOT AI. Just a crutch function. by Anonymous Coward · · Score: 0

    Merely a stupidly over-simplified (compared to real neurons) "neural" net function, based on a few matrix multiplications of fine-tuned weights that turn input into output.

    A crutch function, for when you don't know the actual formula/algorithm to implement.

    AI means it's basically an individual thinking artificial lifeform.

  6. So what do they do with this information? by Anonymous Coward · · Score: 0

    Keep your hospital bed warm for you?

    1. Re:So what do they do with this information? by Anonymous Coward · · Score: 0

      It does sound pretty useless. Maybe if they tried to train it to predict when a patient would be discharged as well as how likely that patient would be to come back, they could use it predict future hospital utilization and help adjust staffing schedules... or parking prices. I wouldn't want that thing suggesting anything about specific patients unless it could explain its reasoning.

    2. Re: So what do they do with this information? by Anonymous Coward · · Score: 0

      If you are really interested and not just making uninformed comments, Google Hospital Dependent Patient or J Teno MD. This is a serious problem and has ramifications beyond finances.

  7. Researchers should work on something else by hcs_$reboot · · Score: 2

    an AI that given a bunch of symptoms, blood analysis, weight loss / gain, ... can tell you a narrow list of diseases you might have ; that would surely beat the best human specialists.

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    Slashdot, fix the reply notifications... You won't get away with it...
    1. Re:Researchers should work on something else by Anonymous Coward · · Score: 0

      IS IT LUPUS?!!

    2. Re:Researchers should work on something else by Anonymous Coward · · Score: 0

      These systems already exist in various stages of sophistication from simple Bayesian inference engines to some deep learning systems. The most useful ones don't pretend they exist to replace the physician but rather exist to augment their thinking by suggesting diagnoses. As a clinician, what you end up doing with such a list is rejecting 80% of the suggestions as either obviously wrong or having already been excluded by previous results. Of the remaining 20%, if you know what you're doing, you probably are already considering 80-90% of the remaining 'suggestions'. It is the one or two unusual suggestions in unusual cases that are actually valuable but at the start of the case, you don't know for sure if this is a case where the 'black box' will be helpful or waste your time. The problem is that most metrics we use to evaluate such systems report things like 'percentage of cases for which the correct diagnosis was in the top N suggestions' without stopping to consider the cost to the clinician to gather enough evidence to reject all the wrong suggestions.

  8. imagine the conversation by Anonymous Coward · · Score: 0
  9. No by Anonymous Coward · · Score: 0

    They just think they did. More 'AI' bs.

  10. It's hilarious by Dunbal · · Score: 1

    It really is. Instead of dedicating their effort to improve humanity and put lawyers out of business, software engineers are throwing major efforts towards putting doctors out of business. Which just goes to show that they can't think further than the last curly brace in their programs. Once all the doctors are out of business, just exactly who you they think become the next target for all the starving lawyers out there left without doctors to sue?

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    Seven puppies were harmed during the making of this post.
    1. Re:It's hilarious by Anonymous Coward · · Score: 0

      Who do you think understands law better. The person who has studied law, or the person who's job it is to implement that law and who has to check every little detail in the law in order to do so, who has to confront all the contradictions?

    2. Re:It's hilarious by Dunbal · · Score: 1

      Who do you think understands law better.

      I can find you any number of layers that will argue either case.

      --
      Seven puppies were harmed during the making of this post.
    3. Re:It's hilarious by dgatwood · · Score: 1

      Often in the same legal proceeding.

      --

      Check out my sci-fi/humor trilogy at PatriotsBooks.

  11. Millennial Awe by Anonymous Coward · · Score: 0

    Whoa! These related concepts are actually close together! Can u believe it ??

    What if we could LITERALLY build a robot that points out the obvious?

    It will be like: THESE THINGS ARE SIMILAR *beep beep*

  12. Risk: 0% by Anonymous Coward · · Score: 0

    Notes: Patient is deceased.

    --sf

  13. Print?! by Anonymous Coward · · Score: 0

    Why, oh why, do you guys keep publicizing research before it's peer reviewed?

    1. Re: Print?! by Anonymous Coward · · Score: 0

      Preprint?!*
      (Typo in title, sorry.)

  14. Words you don't want to hear for 100, Alex by Anonymous Coward · · Score: 0

    "Interesting [x]"

  15. VentureBeat overhype by Anonymous Coward · · Score: 0

    If you read the paper, you’ll find this 15% improvement over previous work, for the 48-72 hour range, has a recall, at 80% precision, of 0.171 ± 0.107. In other words, the recall is somewhere between 7% and 27%, if you want to ensure that you don’t get more than 1 in 5 false positives. If you’re a clinician and you’re trying to use this for a specific patient, it’s useless; a 27% recall rate means that three quarters of the time, it’ll tell you a patient won’t be readmitted and it’ll turn out that she is, and remember, the precision is 80%, so 20% of the time if it says she’s going to be readmitted, she won’t. The work is really interesting; BERT is a really important advance. But clinical language understanding is unbelievably hard, and the area has a long way to go to be reliably useful. VentureBeat is clickbait.

  16. hey Bert by Anonymous Coward · · Score: 0

    Hey Bert

    Yeah Ernie?

    Ain't 'merkin medicine great?

    Yeah Ernie.

  17. Background by jythie · · Score: 3, Informative

    So a little bit of context... this is actually a fairly active area of research and has been for decades. I know people who have been using AI techniques to try to predict readmissions probabilities since the 90s, and some of them have gone on to develop these into commercial products that hospitals use today... so the story here really is not the use case but instead the incremental improvement of this particular corner of AI. I am actually just getting off a project that was trying to apply another area within AI to the same basic problem, though since we were using agent based modeling we probably will not get much attention.

    And this stuff is honestly pretty useful. It helps earmark which patients might need a bit of extra monitoring or guidance, or which ones might benefit from having a nurse check in on them at home. It means figuring out where to proactively spend limited human resources in order to decrease the chances someone is going to end up right back in your ER. Good stuff.