I worked with someone who used to work for a company that installed open source software in K-12. Some issues that have been mentioned already came up, especially with respect to lack of tech savvyness of teachers, but one of the biggest issues was that virtualization was not good enough (this was 4 years ago) to run standard educational software teachers used in the classroom without major annoyances experienced by the teachers.
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I worked with someone who used to work for a company that installed open source software in K-12. Some issues that have been mentioned already came up, especially with respect to lack of tech savvyness of teachers, but one of the biggest issues was that virtualization was not good enough (this was 4 years ago) to run standard educational software teachers used in the classroom without major annoyances experienced by the teachers.