for automated sequencing (on the Perkin-Elmer machines), if you use some of the new Taq dyes, and the new gel methods, you can EASILY get 700+ bases per reaction. also, the repeat sections are more of a problem to the "clone by clone" method - you can't design good sequencing primers that differentiate between the areas being sequenced. with shotgun sequencing, you have a slightly better chance of putting repeat areas in their proper place (this depending on the legenth of the repeat, of course!!)
unfortunately this is the case. the researchers want patents on all the genes they discover, so they will have exclusive research rights to them (unless somebody else pays for the right). however, there is a French team out there (can't remember who offhand) which is trying to beat the Americans to the sequence so they can *donate* the entire genome to the UN, and people will be free to research what they want without having to pay. research moves slowly as it is, and is terribly underfunded (if you consider everything we are attempting to learn). in this case, i hope the French team wins.
i guess i forgot to mention that i'm trained as a scientist. that's the real reason why these articles bother me - i am one of those who will understand all the hardcore science. unfortunately, i'm now a sysadmin, who has a serious love for beer, and who also refinishes furniture in her spare time, so i don't have too much free time to poke around for all the heavy articles. i've become scientifically lazy, and i want all my news from the net, in detail. i really get bothered how these short articles are presented to the general masses. i just don't think they tell enough of the story.
ok, maybe its just me, but articles like this are so annoying. they don't really _say_ anything about the technology. yes, yes, i know about grants, and secrecy, etc etc, but they could at least tell us the composition, structure, or theory behind the 'switch'. for all we know, this was a cute theoretical thing they discovered in the lab that will only work when X, Y, and Z are present, and Jupiter is in line with Mars. it may have absolutely no practical application.
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you SHOULD have the freedom to speed.
you SHOULD have the freedon to murder.
it doesn't make it right, but it is a CHOICE. when we loose the ability to choose, we've lost everything.
well, i placed out of freshman biology.....but i majored in microbiology. does that count??
and i worked in a dna sequencing lab for 2 years. you learn to hate PCR after a while......
for automated sequencing (on the Perkin-Elmer machines), if you use some of the new Taq dyes, and the new gel methods, you can EASILY get 700+ bases per reaction. also, the repeat sections are more of a problem to the "clone by clone" method - you can't design good sequencing primers that differentiate between the areas being sequenced. with shotgun sequencing, you have a slightly better chance of putting repeat areas in their proper place (this depending on the legenth of the repeat, of course!!)
unfortunately this is the case. the researchers want patents on all the genes they discover, so they will have exclusive research rights to them (unless somebody else pays for the right). however, there is a French team out there (can't remember who offhand) which is trying to beat the Americans to the sequence so they can *donate* the entire genome to the UN, and people will be free to research what they want without having to pay. research moves slowly as it is, and is terribly underfunded (if you consider everything we are attempting to learn). in this case, i hope the French team wins.
some research now shows that the "junk dna" actually forms secondary structures that are important in proper protein production
i guess i forgot to mention that i'm trained as a scientist. that's the real reason why these articles bother me - i am one of those who will understand all the hardcore science. unfortunately, i'm now a sysadmin, who has a serious love for beer, and who also refinishes furniture in her spare time, so i don't have too much free time to poke around for all the heavy articles. i've become scientifically lazy, and i want all my news from the net, in detail. i really get bothered how these short articles are presented to the general masses. i just don't think they tell enough of the story.
ok, maybe its just me, but articles like this are so annoying. they don't really _say_ anything about the technology. yes, yes, i know about grants, and secrecy, etc etc, but they could at least tell us the composition, structure, or theory behind the 'switch'. for all we know, this was a cute theoretical thing they discovered in the lab that will only work when X, Y, and Z are present, and Jupiter is in line with Mars. it may have absolutely no practical application.