In the area of console file managers and CLI shell enhancements, there's vshnu, the new visual shell.
vshnu @freshmeat
Vshnu is a visual shell for Linux/Unix finally done right. Best used as an optional color visual mode to a regular command line shell, vshnu is handy for powerful directory listing and navigation, Unix command assembly, special actions on file types, and fileset handling.
Don't forget Alan Carter's remarkable 1000 Minds project, intended even for the severly handicapped:
The 1000 Minds software makes it possible to control all of the thousands of existing programs available for Linux with no more than a single
detectable movement.
I'm pretty mousophobic myself (for the pleasure of the keyboard's efficiency), and use X11 intensely, and so have developed an environment that pretty much lets me leave the mouse alone if I want, except within Netscape (and other mouse-dependent apps) and when cutting and pasting text in xterms. ctwm is the window manager. Code is at
Yeah, this is a shameless plug.
http://www.melloworld.com/otm