Consumers have long since stopped using serial cables in favour of USB. The only real place that they still exist is to get a serial console on servers in a datacenter. The OP suggests that it might be replaced by USB here too, but this is where I disagree. For that sort of task, network-based services are becoming more common. Ethernet is cheap and easy to deploy, and not that difficult to implement in hardware.
Though there'd be nothing to stop a server manufacturer from just building a serial-to-usb converter into their hardware so you get the traditional serial interfaces but using USB.
The serial cable isn't dead yet.
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Consumers have long since stopped using serial cables in favour of USB. The only real place that they still exist is to get a serial console on servers in a datacenter. The OP suggests that it might be replaced by USB here too, but this is where I disagree. For that sort of task, network-based services are becoming more common. Ethernet is cheap and easy to deploy, and not that difficult to implement in hardware. Though there'd be nothing to stop a server manufacturer from just building a serial-to-usb converter into their hardware so you get the traditional serial interfaces but using USB. The serial cable isn't dead yet.