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User: Tough+Love

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  1. Re:8 POSITION, not 8 bit. on Four New DNA Letters Double Life's Alphabet (nature.com) · · Score: 1

    The rest of what you say is correct however.

    Right, when you double numbers they do get bigger, and the 2 cents is correct.

  2. Re:Interesting! on Four New DNA Letters Double Life's Alphabet (nature.com) · · Score: 1

    Hmm, correction, the ribosome actually doesn't need to change much if at all for their 3 bit code, mostly they just need some new tRNAs that incorporate their new nucleotides. The natural machinery should be able to handle it with minimal modification. Yikes.

  3. Re:Interesting! on Four New DNA Letters Double Life's Alphabet (nature.com) · · Score: 1

    Life is 8 bit

    It's not. A codon consists of 3 nucleotides, each of which has 4 different values (i.e., distinct chemical composition) equivalent to a two bit encoding. Total: six bits. The artificially extended version adds one bit to the nucleotide range, times 3 nucleotides, total 9 bits. So there is no way to interpret your joke as correct, sorry. It's not about lacking a sense of humour, it just that the numbers need to add up. For example, "life is braille". Which is actually close to the truth when you look at the way a ribosome works.

    Anyway, like almost anything in nature, it's way more complicated than that because the natural "design" is pretty sloppy, with a lot of redundancy that serves no apparent purpose, so that the 6 bit natural code actually encodes only 20 different protein peptides, plus start and stop, so there are 42 redundant codes out of 64. You could attempt an analogy with ECC, also redundant, but it's not like that, it's more like an ECC designed by somebody who read the first paragraph of the wikipedia page then set out bravely to design their own error correction scheme without bothering to learn the underlying math, giving up in frustration half way through and leaving it for a bunch of code monkeys to make the demented scheme work anyway. Kind of like most software projects, actually. The end result is something that looks like it ought to have some underlying mathematical pattern, but the closer you look at it, the more you want to go back for a do-over.

    Well. That would be a moot point if there was nothing we could do about it, but as these researchers demonstrate, there clearly is. Just to be clear about what they actually did: what defines the genetic code? It's not just four distinct nucleotides, you also need a decoder, which in nature is a ribosome. This research did not go that far. I'm sure they hope to one day, but engineering a 3-bit-per-nucleotide ribosome is a whole lot harder than coming up with 4 new nucleotides. One thing they did get for free is the ability to transcribe 3-bit DNA to 3-bit RNA, because this mechanism doesn't involve any coding, it just requires that the nucleotides pair up uniquely, as they say, like lego bricks.

    Some other researchers previously repurposed some of those redundant natural codes to code for non-natural peptides, another way to extend the genetic code. Another, much harder way, would be to increase the nucleotides per codon. Then, getting back to your joke, we really could create 8 bit life. Left as an exercise for the interested reader to determine whether we want that.

  4. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    It has been super boring watching you in a child state.

  5. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    you're just a broken record now. :)

  6. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    Repeating irrelevant shit doesn't make it relevant.

  7. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    RX 580, number one bestselling GPU on Amazon for many weeks, can be yours for $184.

    (With 8GB VRAM compared to lame 6GB for Nvidia's $280 card.)

  8. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    You have entirely the wrong impression about whether anybody cares about you at all.

  9. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    Nvidia's warehouse full of obsolete cards problem is still not solved according to their own quarterly report. Doesn't matter whether is physically Nvidia's warehouse, or OEM warehouses, or not warehouse at all, just a self store, it is still Nvidia's problem.

    Thanks for your generous crusade to educate the world, and the dainty rhetoric you use to communicate your profound thoughts. What I actually think, you're just a garden variety obsessive-compulsive numbskull with an exaggerated estimation of their own mental abilities.

  10. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    2.) Your contradicting yourself if that 5% of players can justify R&D spending then how is it that the 95% is the lion's share?

    You're a bit of a prat, you know. I simply meant to avoid directly saying that, as a fringe market and you should be grateful that the big boys are willing to throw a few crumbs your way, even though they don't make a large portion of their earnings that way. The money is in the people you like to disparage.

  11. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    Obviously, 95% of Steam players are not fixated on shooter leaderboards, you need to keep things in perspective. Granted, competitive players spend a lot more on their gear, so 5% of players spend maybe 15% of dollars, and margin on those products is higher. That's enough to justify R&D specifically for that segment, but never forget that the other 95% you like to disparage is where the real money is.

  12. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    From Steam's hardware survey last month:

    Biggest winner: Radeon R7, +.19%
    Biggest loser: GTX 1060, -.52%

    Both appearing for the first time that month, Vega beat RTX 2080 TI, .16% to .15%.

    If Nvidia hasn't released a card to compete with the 580 for so long, then maybe it is because they can't. Sure they can release cheap cards, but it would either be junk vs 580 or it would cannibalize their higher priced junk.

  13. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    Apparently, RX 580 is what customers actually want because it does high settings at 1440 just fine, has 8GB for future proofing and costs less than $200. Must drive Nvidia nuts as their warehouse full of obsolete cards gets older and older. Getting close to the point where cheapest solution is landfill. Meanwhile, AMD still making new 580's for huge margin.

    NVidia's response? RTX 2060 to run puddle tracing at 15 FPS. GTX 1660 to give loyal customers a reason not to buy 2080. Sucks to be you.

  14. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    The 8GB Radeon you disparage is actually the top selling card on Amazon. Now wipe that spittle off your chin.

  15. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    So you agree that 3GB is pathetic. Now it's only a small step even for a stunted intellect such as yours to notice that 6GB is also pathetic for a midrange card.

  16. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    3GB, pathetic. Professional review writers.

  17. Re:That's not what is happening on Apple Expected To Move Mac Line To Custom ARM-Based Chips Starting Next Year, Says Report (axios.com) · · Score: 1

    It would be great if they'd do it, I'd love to see Apple fade away some more.

  18. Re:Considering his other claims... on Did A US Navy Scientist Just Invent A Room-Temperature Superconductor? (phys.org) · · Score: 1

    "cold fusion" ... Current hypothesis is conversion of protons and electrons into neutrons.

    Otherwise known as "electron capture", a nuclear reaction. It would create unstable nuclei, which would decay and emit beta rays. The absence of detectable products of nuclear reactions continues to relegate cold fusion to the realm of quackery, no matter how many new reports emerge from the land of Godzilla.

  19. Re:Considering his other claims... on Did A US Navy Scientist Just Invent A Room-Temperature Superconductor? (phys.org) · · Score: 1

    How much confidence does it give you when the patent application includes this text? "The achievement of room temperature conductivity represents a highly disruptive technology capable of a total paradigm shift in Science and Technology, rather than just a paradigm shift. Hence its military and commercial value is considerable." Caps just as I found them.

  20. Re:Considering his other claims... on Did A US Navy Scientist Just Invent A Room-Temperature Superconductor? (phys.org) · · Score: 1

    How is that a "crank" thing? Take a large mass, spin it around.

    You need to work on your definition of "large".

  21. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    mine has 1gb and im ok

    Ha ha, you do have a sense of humor.

  22. Re:Wait. Pottasium = Fermion and Rubidium = Boson? on Researchers Make Coldest Quantum Gas of Molecules (phys.org) · · Score: 1

    Thanks for making my head hurt :)

  23. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    Frankly, it's hard to believe that Nvidia has the gall to sell a midrange card with 3GB, but they do.

    ...The only 3GB NVIDIA card currently manufactured is the entry level 1050.

    Did you ever wonder why you don't have friends? Everybody who makes the mistake of buying this 1060 is going to end up hating Nvidia and all their mealy mouthed camp followers like you.

  24. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    I felt more stupid after reading your post, time to wipe the spittle.

  25. Re:Aaaaannd they gimped it with 6gb of ram on NVIDIA Turing-Based GeForce GTX 1660 Ti Launched At $279 (hothardware.com) · · Score: 1

    Don't be dense, the web is overflowing with complaints about stuttering and stalls due to not enough vram, for example this one or feast your eyes on this. If you want to play those games with your gimped vram then you need to turn down settings including shadows and supersampling. It only gets worse from here. The new standard for mainstream GPUs is 8GB, too bad Nvidia didn't get the message. They will pretty soon.