Does your process require that all of the regexes are tried in turn or is it the case that if it hits one of your patterns that it's marked as spam? If the latter, are you able to rank the patterns from most likely to least likely to be matched? And, if so, can you stop your process once a match is made? If all of those things are true, then you should be able to cut the time/CPU/energy required to do the filtering
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Does your process require that all of the regexes are tried in turn or is it the case that if it hits one of your patterns that it's marked as spam? If the latter, are you able to rank the patterns from most likely to least likely to be matched? And, if so, can you stop your process once a match is made? If all of those things are true, then you should be able to cut the time/CPU/energy required to do the filtering