Since you are going to have to use the same hand for both keysets, you will have to teach your brain to type over again. If you are going to make a keyboard like this, why the heck would you make it QWERTY? Everybody knows that the qwerty layout is poorly suited for computers, and a one-handed dvorak layout and keymaps are already available, I see no reason at all to stick with an outdated inefficient uncomfortable layout.
Anyone with half a brain is going to read book reviews before they read a "scholarly study"
True, but anyone with a full brain would read the scholarly study first.
Since you are going to have to use the same hand for both keysets, you will have to teach your brain to type over again. If you are going to make a keyboard like this, why the heck would you make it QWERTY? Everybody knows that the qwerty layout is poorly suited for computers, and a one-handed dvorak layout and keymaps are already available, I see no reason at all to stick with an outdated inefficient uncomfortable layout.