Even Will couldn't do this. When was the last time an underground letter writing campaign accomplished anything? Especially for WW? If people were writing letters to the Enterprise producers, it'd be over the CRAPPY THEME MUSIC!!
Don't expect a box of seeds. Peter Jackson has stated already that the ending from the end of the books, in which we return to the Shire, will be absent or trimmed down in the the RotK movie, when we get there.
I'm a graduate biochemistry student, and I work in a lab that does biochemical characterization of the crystallins of the lens of the eye. I am extremely skeptical of the theory that the crystallins are in some way mediating this response in the nerve cells.
It is a long story, but the crystallins in the eye serve an essentially structural role. They're present in an absurdly high concentration in order to up the refractive index of the lens tissue. The proteins that evolution recruited to the lens were selected because they resist unfolding and aggregation at high concentration (and, one set of crystallins are thought to help with preventing aggregation of the other crystallins...).
In any case, that tissue is just barely metabolically active (mature lens cells are non-nucleated), and the proteins present have, at most, only vestigal enzymatic activity. From everything we know about crystallins, there is no reason to think that they could ilicit this kind of response. They are highly stable, rather inactive proteins that evolved to last a long time and not mess with stuff.
I don't dispute the study. I just think that the immune system response is a much more plausible explanation.
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Even Will couldn't do this. When was the last time an underground letter writing campaign accomplished anything? Especially for WW? If people were writing letters to the Enterprise producers, it'd be over the CRAPPY THEME MUSIC!!
I hope it has a feature that allows you to turn off april fools jokes. Anything that lessens the tide of fools joke spamming is a plus in my book.
That today is today the first of april, right? Ok, good, just checking.
Don't expect a box of seeds. Peter Jackson has stated already that the ending from the end of the books, in which we return to the Shire, will be absent or trimmed down in the the RotK movie, when we get there.
I'm a graduate biochemistry student, and I work in a lab that does biochemical characterization of the crystallins of the lens of the eye. I am extremely skeptical of the theory that the crystallins are in some way mediating this response in the nerve cells.
It is a long story, but the crystallins in the eye serve an essentially structural role. They're present in an absurdly high concentration in order to up the refractive index of the lens tissue. The proteins that evolution recruited to the lens were selected because they resist unfolding and aggregation at high concentration (and, one set of crystallins are thought to help with preventing aggregation of the other crystallins...).
In any case, that tissue is just barely metabolically active (mature lens cells are non-nucleated), and the proteins present have, at most, only vestigal enzymatic activity. From everything we know about crystallins, there is no reason to think that they could ilicit this kind of response. They are highly stable, rather inactive proteins that evolved to last a long time and not mess with stuff.
I don't dispute the study. I just think that the immune system response is a much more plausible explanation.
!splut