Well, the current incarnation of Opera is based on Chrome, but they've made a lot of positive changes to the code base. I don't really use Chrome much though, so I'm not sure exactly how Deep the differences go.
And anyone who says Ibuprofen or Tylenol works better for them is likely a DEA shill or got placebos, because that's a load of crap. I can understand the nausea, yes, but to say opioids are less effective than over the counter counter analgesics is ridiculous.
That's not entirely true. There are people who do not metabolize opioids effectively. They are, however, very rare. I'd guess most people who say the above actually have little or no experience with opiate painkillers, and are instead spouting BS they heard from someone else in order to look informed.
Standard release opiates are far more potent, because they are absorbed far more quickly. An SR tablet produces 3x the concentration as an ER tablet, because they're metabolized 3x as quickly.
Or perhaps the opiates I use are voodoo and work in exactly the opposite manner they do for everyone else.
Yeah, that was one thing that annoyed me about the article. 5x the strength of what? Codeine? Hydrocodone? Morphine? Oxycodone? Hydromorphone? Fentanyl? Buprenorphine? Carfentanil?
For an actual answer, according to the description of the person above claiming to have been in the trial (assuming they're correct in the dosing comparison) it's about half the potency of oxycodone.
You cannot use non-opiate placebos for control in opiate trials. Not only would it be blindingly obvious to everyone involved who was on the control, it would also violate every standard of medical ethics.
It may not have been that the drug was incapable of meeting your pain needs. I was on the fentanyl transdermal patch as well, and was having absorption issues resulting in the patch wearing out unpredictably. When I moved back to oxycodone from fentanyl, I went through basically the same thing you describe when you switched to Zohydro. In addition, I also went through intense opiate withdrawal despite being on opiate therapy (again, pretty much as you describe, though shorter in length). There are certain people who fentanyl affects that way. It's phenomenal when it works right, and hell when it doesn't.
I'm glad I wasn't on fentanyl for long enough to go through the lengthy withdrawal you did; I got off it in relatively short order and will not ever again use the transdermal form.
Oh, comfortable masks most certainly exist. They tend to be full enclosure masks though, in order to be supported by structures other than the bridge of your nose. As a result, they're hideously expensive compared to half-masks.
The one fortunate thing is they're building back into Chrome what they lost when they stopped developing Presto. It's slow, but it's happening. I still miss things like Ctrl-Z re-opening closed windows, but they've regained a lot of the ground they lost in the changeover.
I still really miss per-site options, which haven't made it back into Chrome-based Opera.
It can even include those above you in the chain of command. Anyone below the highest person in the chain of command whose backing you have is also a potential criminal target.
And this is the sort of thing that leads to the generalization of the Slashdot membership being composed almost entirely of virgins, or at least those who are not capable of sustaining a relationship with a woman that doesn't involve large cash payments.
Most things labeled "indie" only pretend to be intellectual. Most of them are just as shallow and full of shit as any big commercial product, just in a different way.
The existence of US-sponsored fascist groups in Venezuela does not, in any way, invalidate the point being made.
Your comment is irrelevant unless it is your contention that, indeed, every single person who opposes Maduro is a violent fascist.
I suggest going to Venezuela and attempting to publicly broadcast a dissenting opinion. See how long you're left to your own devices. I suspect it wouldn't be a particularly long time.
The Arab Spring clearly demonstrated why unlimited democratic power in the hands of the people is a recipe for disaster.
Democratic power only works if it is strictly limited in scope. If it is not, people tend to elect sociopaths who will confirm their biases whilst engaging in their own personal corrupt predilections.
Indeed. The larger the development, the cheaper it is to buy off a small number of local politicians in comparison to fairly compensating a large number of property owners.
If the US was broken up into a large number of smaller republics, it would also be easier for the populace of any one of them to deal with this type of politician in a manner they deserve.
Slashdot Mirror
Well, the current incarnation of Opera is based on Chrome, but they've made a lot of positive changes to the code base. I don't really use Chrome much though, so I'm not sure exactly how Deep the differences go.
And anyone who says Ibuprofen or Tylenol works better for them is likely a DEA shill or got placebos, because that's a load of crap. I can understand the nausea, yes, but to say opioids are less effective than over the counter counter analgesics is ridiculous.
That's not entirely true. There are people who do not metabolize opioids effectively. They are, however, very rare. I'd guess most people who say the above actually have little or no experience with opiate painkillers, and are instead spouting BS they heard from someone else in order to look informed.
Standard release opiates are far more potent, because they are absorbed far more quickly. An SR tablet produces 3x the concentration as an ER tablet, because they're metabolized 3x as quickly.
Or perhaps the opiates I use are voodoo and work in exactly the opposite manner they do for everyone else.
Visit a chronic pain clinic. Until then, fuck right the hell off.
Yeah, that was one thing that annoyed me about the article. 5x the strength of what? Codeine? Hydrocodone? Morphine? Oxycodone? Hydromorphone? Fentanyl? Buprenorphine? Carfentanil?
For an actual answer, according to the description of the person above claiming to have been in the trial (assuming they're correct in the dosing comparison) it's about half the potency of oxycodone.
Looks like you're not aware of how opiates work.
You cannot use non-opiate placebos for control in opiate trials. Not only would it be blindingly obvious to everyone involved who was on the control, it would also violate every standard of medical ethics.
It may not have been that the drug was incapable of meeting your pain needs. I was on the fentanyl transdermal patch as well, and was having absorption issues resulting in the patch wearing out unpredictably. When I moved back to oxycodone from fentanyl, I went through basically the same thing you describe when you switched to Zohydro. In addition, I also went through intense opiate withdrawal despite being on opiate therapy (again, pretty much as you describe, though shorter in length). There are certain people who fentanyl affects that way. It's phenomenal when it works right, and hell when it doesn't.
I'm glad I wasn't on fentanyl for long enough to go through the lengthy withdrawal you did; I got off it in relatively short order and will not ever again use the transdermal form.
Oh, comfortable masks most certainly exist. They tend to be full enclosure masks though, in order to be supported by structures other than the bridge of your nose. As a result, they're hideously expensive compared to half-masks.
Opera 15 (now 19) isn't FireFox, it's Chrome.
The one fortunate thing is they're building back into Chrome what they lost when they stopped developing Presto. It's slow, but it's happening. I still miss things like Ctrl-Z re-opening closed windows, but they've regained a lot of the ground they lost in the changeover.
I still really miss per-site options, which haven't made it back into Chrome-based Opera.
To cops in the US, there's no such things as "law abiding citizens." There are two classes of people: cops, and potential criminals.
It can even include those above you in the chain of command. Anyone below the highest person in the chain of command whose backing you have is also a potential criminal target.
They usually stop trying to push the same thing when it fails once though. That's what differentiates MS from many other companies.
And this is the sort of thing that leads to the generalization of the Slashdot membership being composed almost entirely of virgins, or at least those who are not capable of sustaining a relationship with a woman that doesn't involve large cash payments.
Most of the addicts I've known do all those things. None of them are incompatible with addiction. At all.
Most things labeled "indie" only pretend to be intellectual. Most of them are just as shallow and full of shit as any big commercial product, just in a different way.
"Legislation" and "common sense" are almost always mutually exclusive terms.
Doh, that should have been $200...
Nope, but filling your hands full from your bloody nose and then covering the entire front of their $20 sports jacket in blood works wonders.
The existence of US-sponsored fascist groups in Venezuela does not, in any way, invalidate the point being made.
Your comment is irrelevant unless it is your contention that, indeed, every single person who opposes Maduro is a violent fascist.
I suggest going to Venezuela and attempting to publicly broadcast a dissenting opinion. See how long you're left to your own devices. I suspect it wouldn't be a particularly long time.
I guess that rules out calling Hitler, a democratically elected politician, a dictator.
A democratic election does not prevent the elected individual from being a dictator.
The Arab Spring clearly demonstrated why unlimited democratic power in the hands of the people is a recipe for disaster.
Democratic power only works if it is strictly limited in scope. If it is not, people tend to elect sociopaths who will confirm their biases whilst engaging in their own personal corrupt predilections.
It's also worked brilliantly for China.
Indeed. The larger the development, the cheaper it is to buy off a small number of local politicians in comparison to fairly compensating a large number of property owners.
If the US was broken up into a large number of smaller republics, it would also be easier for the populace of any one of them to deal with this type of politician in a manner they deserve.
I use propane, which is a gas you insensitive clod!