Good desktop security is the answer... tight group policy and regular security audits. We go through a few OUs a week on our domain, putting a login script for those users that dumps their installed applications to a text file on our network. We then wrote a little app to search that file for a list of banned app names (of which skype is one). Its not perfect, but its easy and free.. There are plenty of commercial utils out there that catalogue and restrict software if you cant be bothered to do it the "hard" way.
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Good desktop security is the answer... tight group policy and regular security audits. We go through a few OUs a week on our domain, putting a login script for those users that dumps their installed applications to a text file on our network. We then wrote a little app to search that file for a list of banned app names (of which skype is one). Its not perfect, but its easy and free.. There are plenty of commercial utils out there that catalogue and restrict software if you cant be bothered to do it the "hard" way.