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TigerCloning

BeaverWise writes "Looks like puss and boots is coming back. The last known Tasmanian tiger, or thylacine, died in captivity in 1936, but a team of Australian biologists believes the animal's extinction may simply be a 70-year hiccup. DNA from a Tasmanian tiger has been found, and cloning is under way."

14 of 348 comments (clear)

  1. Cool. by Spankophile · · Score: 4

    I wonder if they'll have to repair the Tiger DNA with that from frogs, then we can have spontaneous sex-changes and let them reproduce!

    1. Re:Cool. by bob_jordan · · Score: 4

      What if they simply don't have enough?

      Tiger tiger burning bright.
      Two left paws? Wait that's not right!

      Bob.

  2. If you can clone an extinct animal... by Panamon777 · · Score: 5

    ...to what extent do you repopulate the wild? Do you produce three or four for display in zoos, or do you reproduce millions of them (a la the Passenger Pigeon) to put them back into nature at the levels they once were?

    This does, of course, assume that the cloning works perfectly. If it does, it'll have a significant impact on the Endangered Species list - don't worry about killing off endangered animals, because "they" can always make more! It might do more harm than good in that respect.

    Evan

    1. Re:If you can clone an extinct animal... by Suidae · · Score: 4

      The problem with reintroducing them into the wild was pointed out quite clearly in Jurassic Park. Many behaviours of a species are learned from the parents, once a species has gone extinct, these behaviours are lost, and any cloned animals are simply NOT going to be the same.

      You can make a bunch and release them in the wild, but their genetic diversity will be destroyed, and their learned hunting skills and social structure will be gone. The best we could hope for would be a bad copy of the original.

  3. Breeding population by FascDot+Killed+My+Pr · · Score: 4

    I didn't read the story very closely so I don't know if it mentions how many tasmanian fetuses (fetii?) they have. If it's a small number, though, this exercise is relatively pointless. Let's say it was one female and one male. They make 50 copies of each and breed the males with the females. The children of these parents will actually be genetic siblings. You don't want to interbreed siblings for well-known reasons.

    Two females and two males are only slightly better--the children will consist of three groups: full siblings, half-siblings and strangers. But the grandchildren will be (carry the one, add two) all full and half siblings? Anyway, you can see my point. They need a "breeding population of genetic samples" if they want to do more than a publicity stunt.

    I should also note that while the animal produced IS a tasmanian whatever, this extinction/cloning cycle will probably result in long-term speciation. That is, X years from now (for some X less than the "normal" amount) these tasmanians will be a different species than the original. Why? Because we chose a non-random sample AND subjected the new animal to new conditions (unless they plan on releasing them into the wild).
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    1. Re:Breeding population by Reziac · · Score: 5

      Firstoff, animal breeding is my professional field, and after 31 years I think I have a clue:

      Someone says: "They make 50 copies of each and breed the males with the females. The children of these parents will actually be genetic siblings. You don't want to interbreed siblings for well-known reasons."

      You don't know what you're talking about. Firstoff, in animal husbandry "interbreed" means "crossbreed within the same general type". Frex, a crossbred dog would be say a Malemute and a Labrador Retriever (from two different breed groups entirely) and an interbred would be a Lab and a Golden Retriever (from two similar breeds, but still not a purebred).

      Second, what you meant, to wit "inbreeding", does ***NOT*** IN ITSELF ***CREATE*** problems, contrary to popular perception. All inbreeding does is *concentrate the genes you already have*. If they're bad you get worse results. If they're good, you get better results. If you want to find out exactly what genes are really present in your breeding stock, inbreeding will display both the results of homozygous recessives (such as most colours other than black) and the results of homozygous dominance (such as better muscling in beef cattle) much more quickly -- in one or 2 generations, with no GUESSWORK required. This applies to both positive and negative traits. The sooner you know what genes you have in your herd, the sooner you can breed for OR against that trait.

      Nearly all commercial livestock species have been intensively inbred for over 100 years, because inbreeding FROM SOUND DEFECT-FREE STOCK produces consistent, predictable, uniformly positive results. MOST animals in the wild inbreed to some extent, because they don't have any "moral" objections (they will cheerfully breed their siblings, in fact the tendency is to *want* to breed within animals that smell the same, ie. are closely related), and because generally there is not a lot of movement between population territories.

      The notion that inbreeding is automatically BAD comes from the fact that in animals with a LOT of genetic defects in the gene pool, such as humans, ANY time you double up on a set of their genes, chances are you've also doubled up on something Bad. The average human carries an average of 25 to 75 genes for LETHAL defects. The average dog carries for one or two. Beef cattle generally carry NONE. Wild animals, per observational evidence, tend to carry FEW or NO lethal defects -- because unlike with humans who have access to medical treatment, in the wild natural selection does its job: An animal with a defect doesn't survive long enough to reproduce; therefore defective genes tend to eliminate themselves.

      I'd say I was sorry about the long rant, but I hear these ignorant statements all the time and I get sick of it. I could draw an equally-valid analogy to the effect that the linux community is inbred and therefore defective.

      --
      ~REZ~ #43301. Who'd fake being me anyway?
  4. This is the right thing to do by stevens · · Score: 4
    this isn't the right thing to do. Why? Because as much as we might like to, you can't turn back the clock - a principle made abundently clear by the Second Law of Thermodynamics.

    Actually, we can turn back the clock (i.e., bring back the tiger). You seem to be arguing that we shouldn't because we can't. That's just silly. We can and we will.

    Like it or not, life follows a plan, and once something has happened we need to deal with it and move on.

    Actually, there is no cosmic plan; we learn what we can about the world through own own brains and try to get along as best we can. And humans deal with nature not by adapting (in the sense of passive adjustment), but by understanding and adapting it to us. Tiger extinct? Let's learn to bring it back. Hell, we're close to bringing back the Wooly Mammoth from the last ice age, 10k years ago.

    Using science to figure out the universe around us is what we do. This is just one more example--and if it brings back a tiger, then it's a net benefit, so I don't see the problem.

    Steve
  5. And in related news.... by ch-chuck · · Score: 4

    this technique is actually the scientific basis for the Second Coming

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  6. People are bad, mmkay? by vslashg · · Score: 4
    Wait. If our killing of the Tasmanian tiger was a natural product of Darwinism, then why isn't our bringing one back also natural?

    Oh, that's right, I forgot. If a beaver builds a dam, that's nature; if we build a hydroelectric plant, that's science. Humans are intrinsicly evil and have no place on this planet. [end sarcasm]

    All that's happened is that we've got a workable intelligence, so instead of creatures evolving to the environment, we're creatures changing the environment to suit ourselves. I still don't see why this kind of thing isn't considered nature. People seem to act like cloning is against the rules, to which I say, what rules?

    1. Re:People are bad, mmkay? by Sloppy · · Score: 4

      Heh, interesting. A beaver's dam is part of the beaver's "extended phenotype." Hoover dam is part of a human's (a group of humans'?) extended phenotype. Tasmanian Tiger, which used to be an animal all on its own and probably didn't do much evolving in the presence of humanity, will now also be part of human extended phenotype. That life form will be a manifestation of human genes that create minds that want to play God. Tasmanian Tiger, descended from apes.


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  7. Tasmanian Perspective by Basalisk · · Score: 5

    I live in Tasmania, and so I feel this is quite close to home. When White Tasmanians came here, there was a thriving population of Tasmanian Tigers, or Native Wolves as they were called back then. It was thought that there population could cope with the amount of hunting that was going on. However by the late 1890s, They were becoming scarce. They weren't as easy to find. The last of the species died in Hobart Zoo in 1936. It was thought that the Thylacine was extinct, as no confirmed sightings have occurred since then. There are many unconfirmed sightings every year. Some people think that there is still a small remainant colony in some parts of Tasmania, mainly the SW World Heritage Area because of it's remoteness. That part of Tassie is still very wild.
    The Thylacine would probably benefit from being ressurected. If there is still a wild group, this may help to boost their numbers. I think the tiger should be brought back, not just because it is an extinct animal, or possibly endangered (unlikely tho), but because it represents a group of mammals (I think is) unique to Tasmania, The Carnivorous Marsupials. Most carnivorous marsupials that developed on mainland Australia were squeezed out by the dingo, a close relative of the dog. The dingo did not reach Tasmania and as such its CM populations were left undisturbed. The Tasmanian Devil is also a CM. However the thylacine was the only active hunter. I just hope that enough genetic diversity can be found among the 'samples' to provide a stable population.

  8. Re:Great news by TheCarp · · Score: 4

    Your making the assumption that the "Evolutionary Process" is a process that is heading towards a specific goal. As if the process has some sort of will, some plan.

    Natural selection is truely a simple concept, and can be summed up in 2 statments:

    1) Change happens
    2) Organisms that can survive and multiply better than others, will do so.

    The ice age comes, any animals that can survive in extreme cold will survive. They will adapt to it. Animals with genes for thicker fur and better metabolism will survive and pass on those genes more readily than those that don't have them.

    Its simply a model for application to situations. You could say that the environment became unfavorable to these tigers, as they had more predators. They were unable to adapt in time to survive these predators.

    Thats no moral judgement. That doesn't mean the tigers shouldn't exist because they were unable to survive hunting. It just means that they didn't.

    Nature isn't moral. It just is.

    --
    "I opened my eyes, and everything went dark again"
  9. Re:Maybe it IS possible by Nicolas+MONNET · · Score: 4

    In principle (given sufficiently advanced genetic technology) it might be possible to identify and eliminate the recessive lethal alleles from the tiger gene pool. It would then be safe for cloned animals to interbreed.

    I think that, in order to determine recessive lethal genes, you need to have a sufficiently large population ... currently , such genes are discovered through epidemiology ... so this process would be quite impossible.

    Anyway, the danger of cross breeding is to the immediate offbringing. After a few generations anyway, provided the first children don't die too early, the problem should go away.

  10. Re:Is this the right thing to do? by Mike+Connell · · Score: 5

    > It's the way things work, and fighting it is only self-congratulatory nonsense.

    Not meaning to be rude, but: Utter nonsense.

    "Survival Of The Fittest" isn't some great plan - it's a description of a process. You seem to be saying that we should just lie back and take whatever comes; after all, if something becomes extinct then it just wasn't fit enough, and it's somehow right that it should be dead! What if we nuked half of the planet? Oh, "Survival Of The Fittest", those creatures weren't fit enough to survive, and we shouldn't try to save them...

    If you really want to base your view on "Survival Of The Fittest" as a big unbreakable rule, look at it this way. That tiger has proven to *be* fit even after it become extinct. By being an interesting creature, it is fitter than others that we might bring back. Another example: furry seals get more protection than slimy eels. Why? Because they are *fitter* (cuter).

    best wishes,
    Mike.