Eliza for Spam
Saint Aardvark the Carpeted writes "Check this out for sheer genius...This guy has posted to Perl Monks a script that uses the Perl Eliza module to respond to spam. Check it and contribute your suggestions for improved vocabulary." The downside of course is that spammers never set their reply correctly (which I think is forgery, and should be treated as such) so this is probably more academic then useful, but its definitely funny.
And how does it make you feel that eliza responds to spam?