Blind Computing?

moro asks: "One of my friends was recently blinded in an accident. The problem has arisen that he needs the use of his computer, but all of the interfaces for the blind are either EXTREMELY cumbersome, or OUTRAGEOUSLY expensive, if not both. Does anyone know of a good computing solution for the blind? Are there any open-source projects that specialize in this kind of stuff?" If there are blind programmers and sysadmins, then I'd hope the technology that enables them to do their jobs wouldn't be too cost-prohibitive to be brought into the home as well. So, are there any leads on affordable technology that will bring computing to the blind?