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Designer Babies, Version 1.0

Stickerboy writes: "A 30 year-old woman in Chicago gave birth to a pre-pregnancy genetically screened and selected baby 17 months ago, which is being reported in the Journal of the American Medical Association today. Doctors at the Reproductive Genetics Institute in Chicago took 23 eggs from her, screened the eggs for a gene that causes an early form of Alzheimer's, and then fertilized and implanted the eggs back in her womb. Shades of the movie Gattaca - this is a good specific development, but the start of a very controversial trend. Read more about it in the Washington Post or read the abstract in JAMA."

7 of 514 comments (clear)

  1. Screening != GM by Bonker · · Score: 5, Insightful

    All doctors did was select an unaltered embryo that had a better chance of developing into a healthy adult. They didn't change the embryo in any way, nor did they give any advantage to the mother or embryo.

    Some doctors encourage people who are at risk of genetically transmitted diseases to have their unborn fetuses screened for those same diseases so that they have the option of aborting early in the pregnancy.

    This merely takes that practice a step further, while eliminating the controversy of abortion.

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  2. Natural Selection? by Em+Emalb · · Score: 5, Insightful

    From the article:
    "Without the screening, the newborn would have faced fifty-fifty odds of becoming hopelessly senile by the time she was 40."

    This is a terrible thing. I am really sorry to hear that this *might* happen by the time she/he is 40.

    Well, IMO, this goes against natural selection. Weaknesses are inherent in all forms of life. And in this case, the weakness is basically being forced out of the child. I don't think this is a good thing, and here is why...

    What happens when the governments start screening every child that is born for any inherent form of "weakness"? Will those children never receive the chance to live? Will they be branded "inferior"? This has the potential to be an extremely bad thing.

    If you want a child so badly, lady, go ADOPT ONE.

    There are literally thousands of unwanted children out there that need and want a family.

    What is so wrong about going this route as opposed to paying thousands for a procedure like this? You help a child already alive, and more importantly, you give that child a chance to have a better life, and that is what it's all about.

    of course, this is my opinion, and I am sure I will be slammed most heartily....

    *cracks open a beer and waits*

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  3. Re:Extension of evolution? by volsung · · Score: 5, Funny
    Of course, anytime humanity plays God, there room for abuse and evil (breeding sex slaves, mercerary warriors, etc).

    It is interesting how two industries that are always well-funded are the porn industry and the military. :)

  4. Re:What else can be found by Bonker · · Score: 5, Insightful

    Not only the diseases, but when (and if) we can pre-screen for intelligence, strenght, certain characteristics, won't we be creating a 'super human-race'?

    Very simply, you can't screen for most human traits. Period. Sorry, go to the back of the line.

    Besides the fact that most traits are caused not by one gene, but by the interaction of dozens of genes and the proteins they create, you have to consider that almost all human traits develop in accordance to someone's environment.

    Thusly, if Albert Einstein had been raised in an environment where he wasn't exposed to mathematics or the written word until he was 30 years old, he probably wouldn't come across quite as bright as he was. If he had been raised in an environment where he was not exposed to speech-- The so called 'Forbidden Expirement'-- he probably would come across as being pretty retarded.

    If Michael Jordan had not had the opportunity to work hard in his youth and become athletic, he probably wouldn't be the sports superstar he is today. He couldn't just 'develop' those traits and skills later in life.

    Say you're an intelligent but pudgy software engineer/couch potato type and you actually manage to get the doctors to screen embryos and sperm most likely to create an athletic individual. If the child created may have a better chance of becoming atheltic, but if he follows his parents example, he will probably be just as pudgy.

    Now the one trait that you *can* screen for is gender, mostly because the relationship between X and Y chromosomes has been fairly well observed even if the science behind all the related protein interactions has not been fully plumbed yet.

    This raises some scary possibilities, especially in parts of the world where reproduction is controlled by government (China) or families are encouraged to have male children. (Quite a bit of the world, actually.) Having a gender imbalance will do a number on women's rights.

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  5. Evolution vs Breeding Out Intelligence by allanc · · Score: 5, Interesting

    Okay, two immediate thoughts come to mind with relation to this.

    First off, with the way that human mating works nowadays, there really isn't much evolutionary motivation. You date people who you find attractive for whatever damn fool reason you have rather than for the purpose of creating healthy offspring. I, for instance, tend to prefer dating women who find fat, bearded computer geeks attractive. That's not an evolutionarily sound move on my part, but that's not going to make me dump my lovely girlfriend. So this development makes it possible for Humans to actually take control of evolution and start breeding out diseases and infirmaties.

    However, the problem that immediately comes to mind is something that dog breeders have found over the years. People started breeding for certain traits such as soft coat, ears that are floppy in exactly the right way, short tails, etc. While this makes for very pretty dogs, it leads to the problem that the average Dalmation, far from rescuing its brethren from Cruella DeVille, could just barely rescue itself from a small, wet paper sack. And that's only if it had 100 other dogs helping it. And the wet paper sack also had food in it that they wanted to get to. And maybe was perforated. Which is why sheepdog owners are, last I heard (which was, admittedly, years ago), fighting tooth and nail to keep their breed out of competition. They raise sheepdogs to be /smart/ and /strong/ and /useful/. Not pretty.

    The point I'm trying to make is that genetically manipulating which kids we have to screen for diseases is fine by me, but I'd hate to live in a future where people start screening their reproductive cells so that they only have pretty babies. They'll probably be able to play games with Dalmations on the same intellectual level.

    --AC

  6. Terminology beats thought by joss · · Score: 5, Insightful

    Just using that phrase "designer babies" determines the conclusion. Put out a poll...

    "are you in favor of designer babies" - no

    "should potential parents with inheritable diseases have the right to pre-screen their embryos for those diseases" - yes

    Then we get the "look at all the wonderful cripples like Hawkins etc...." argument. Well, the foetuses you discard have at least as much chance of turning out well as the ones you keep. There are plenty of great humans who have nasty genetic diseases, but we have no way of telling what geniuses we've missed because the lack of screening meant some doomed half-wit runt got born instead.

    And while I'm ranting... Gattaca wasn't that scary. I'm in favor of a world where more people look like Uma Thurman.

    Anyway, I better quit before I start proposing full scale eugenics and saying "just because Hitler gave it a bad name doesn't mean it's wrong, after all, if his policies had been implemented Hitler would never have been born in the first place..." that would ruin any credibility I have. Oh shit, too late, just kidding, but I do have a gut reaction against the "this is what nazi's wanted = bad". Decent roads and punctual transport would get discarded too with those arguments.

    Personally, I have more faith in nature combining things in the right way than a bunch of fuckwit genetic engineers. But, I don't think it's fair to tell people "it's illegal for you to try and avoid having a child who dies early - I'm not comfortable with that". You know what - nobody asked you to be comfortable with it, it's none of your business.

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  7. A pretty good thing on average by Nurf · · Score: 5, Insightful

    I think being able to adjust ourselves genetically is a good thing on average. We just have to be careful that we dont:

    1) Decrease the overall genetic diversity of the population. ie. Mass produced specific genes are probably a bad idea.

    2) Create people that can't mate with "normal" humans.

    As long as (2) applies we are adding to the gene pool, and it think there are enough people having kids the natural way out there that (1) will be very difficult to make happen (gene-implanting virus epidemics aside).

    The possibility exists that a modification could be made that ends up having bad consequences for the recipient decades later. This is the nature of reality. The risk means that people will think twice before doing it, which should provide some handy negative feedback. You have to consider the probabilities.

    Would I be willing to make this choice for my offspring? Yes. I indirectly make this choice by picking a mate anyway. I won't make a choice carelessly, and I would only do it if I saw real benefit for my kids. Many choices you make in your lifetime have a significant impact on those around you. It's the nature of life, rather than the nature of this particular problem.

    For those that would point out that my children would bear the lifelong burden of my choices, I agree and say "So what?". It would be one of many such choices, and I feel no moral qualms about making them. It is my responsibility to do so.

    Just to be clear, I know we are currently in the "remove things we know to be bad" stage rather than the "designer water-breathing" gene stage. I'm just looking ahead a bit.

    I find most of the complaints against this sort of thing to be in the gut-feeling-looking-for-a-pseudo-logical-argument category. The remainder have so far made points that haven't convinced me.

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