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Bionic Retinas Give Patients Sight

The Noof writes " Yahoo News is running a story about patients who have been given partial sight thanks to implants of silicon-based bionic retinas. " The article notes that the implant is having a "rescue effect" on the other components of the retina, restoring cells around the implant and making them useful again." Amazing stuff.

25 of 197 comments (clear)

  1. Was I the only one...? by doorbot.com · · Score: 3, Funny

    For some reason, I read this story's title as "Bionic Retinas Give Patents Sight" which I thought was a reference to issuing/implanting bionic retinas in USPTO employees so that they would be better able to read the rediculous patents which cross their desks.

    Maybe I could use a set of bionic retinas...

    1. Re:Was I the only one...? by Oculus+Habent · · Score: 3, Interesting

      People who are born with visual impairments that can be corrected with technology (i.e. not visual cortex failure) have very low chances of worthwhile results.

      When the brain never receives stimulus in a cortex, it never forms any pathways. That portion of the brain, while functional, makes no connections with anything else. A person with visual implants might be able to see as well (maybe better) than you and I, but they wouldn't understand what they saw. They would have technical function but no visual acuity.

      This same issue has been demonstrated in people who grew up deaf. They may obtain the ability to hear, but understanding is something they can most likely never acheive. The new sense has missed the "formative" years of the brain, and the individual will never be able to use the sense as others do.

      For those who have a hard time comprehending this concept (which is completely understandable), liken it to suddenly having wings surgically attached. Sure, you may have wings, and it's physically possible to fly, but you've never had wings before. They don't work like arms or legs, and you'll probably never learn to control them well enough to fly.

      If you still aren't sure, watch At First Sight. It shows quite well the problems a person would face were they to regain sight. And keep in mind, he once could see.

      --
      That what was all this school was for... to teach us how to solve our own problems. -- janeowit
  2. question by CmdrSanity · · Score: 4, Insightful
    So I guess the most obvious question is: how long before the bionic retina is better than the real thing and would you get one?

    Neat stuff.

    1. Re:question by istartedi · · Score: 5, Interesting

      Let's build on that. How dense could the sensors get before the optical limits of the eye would become the bottleneck?

      Also, since these things are using the photo-voltaic effect to generate the electrical impulse, isn't there a limit to how well they would work in low light? Can that limit be overcome? Could they build units that grabbed inductive power from a transmitter in your glasses to overcome that problem, or maybe even allow super night vision? Will future soldiers be encouraged to get such implants? On the opposite side of that equation, would they allow you to look at the sun without being damaged?

      --
      For all intensive purposes, "whom" is no longer a word. That begs the question, "who cares"?
    2. Re:question by bleckywelcky · · Score: 3, Interesting


      Absolutely seriously. My eyes aren't in that bad of shape, but they aren't exactly perfect either. Plus I can't see IR or UV. If bionic eyes were tested enough to be completely safe and healthy for the body, as well as 99.999% reliable (preferably 100%), they could be considered a reliable replacement. Add in a few features like integration into computing systems, switching between UV detection, IR detection, and traditional visible light detection, etc, and you would have some really awesome eyes. I would absolutely pick up a pair of these if they were cheap enough and fail safe enough. It would almost be a step toward Predator type systems, just get me a shoulder cannon and I'm all set :) . Just imagine being able to step up to a computer console and plug yourself in. Or even better, using secure IR signals (make sure to switch out of IR detection mode, heh) or WiFi signals. Add in a few memory modules, and you can carry all of your data with you. This would be great.

    3. Re:question by Aix · · Score: 5, Interesting

      I think you underestimate just how good human biological vision really is. It is easy to think at first that rods and cones are just like CCDs or pixels or whatever. It is far more complicated than that. In fact, there is extensive research that demonstrates that you can see in higher resolution than should be optically possible. The reason this works is complicated, but basically comes down to the fact that there is an immense amount of inter-cellular interpolation going on. It can be modeled simplistically as an array of voltage sources.

      A good starter paper might be the classic "What the Frog's Eye Tells The Frog's Brain" by McCullough, Pitts and Lettvin. (From MIT's RLE Lab in the 50's) More recently, Marr's stuff is supposed to be very good.

    4. Re:question by BWJones · · Score: 3, Informative

      As a retinal scientist who knows more than a bit about the problem, I am saying 30 years.

      --
      Visit Jonesblog and say hello.
  3. Improvements by chill · · Score: 4, Interesting

    How long until they offer an "improved" version, that has an overlaid clock/calendar, or just a HUD connected to the implanted, bone-conductive phone?

    How about that "cybog" professor and all the hassles he had getting past airport security. While these things are tiny, I can easily forsee a future whene implants are regulated country-by-country.

    "Sorry sir. Memory-storage implants are not legal in Canada. You must reboard the airplane."

    Johnny Mnemonic, here we come.

    --
    Learning HOW to think is more important than learning WHAT to think.
    1. Re:Improvements by Wylfing · · Score: 3, Funny
      Yes, if you look very closely at these bionic eyes you will see the words "Zeiss-Ikon" etched onto the irises.

      --
      Our intelligent designer has never created an animal that we couldn't improve by strapping a bomb to it.
  4. Can it be DoS'd? by Jon+Howard · · Score: 4, Interesting

    What kind of interference will upset the function of this device which wouldn't affect a normal eye? Can it be remotely manipulated in such a way as to malfunction or function in a way that a remote attacker may desire it to function?

    The fact that I have to ask these questions makes me hesitant to put electronics in my head, but I can imagine that the concern would be less for someone who couldn't see without them.

  5. That's just great. Really. by dlek · · Score: 4, Insightful

    It's nice to see technology that really improves people's lives, instead of possibly giving slight and ambiguous gains to their productivity or make it that much easier to send 10-word messages to other people within urban areas. I like advancements in 3d vid cards and such as much as the next guy, but this is what technology's really all about. Helping the blind see again? Excellent. I'd give back the Internet if it would find us a cure for cancer.

  6. Re:Full Article Text by 0x0d0a · · Score: 5, Funny

    Yes, it would be awful if Yahoo got slashdotted, wouldn't it? Better post the article, just to make sure.

  7. Limited Potential by Jon_Katz+(Paranoid+F · · Score: 5, Informative

    While this indeed is a great innovation, we must remember that this has only been tested by people affected by retinitis pigmentosa. Whether the optical implants can be used to restore sight for people from eye injuries or other diseases remains to be seen.

    A lowdown on retinitis pigmentosa can be found here.

    1. Re:Limited Potential by mr_exit · · Score: 5, Interesting

      WOW this is the greatest news I have heard all year.... it has totally made my day.

      Ok calm down... explanation time..

      I have had retina reatachment surgery 3 times in two years. this is where they take your eyes out, cut open the 6 rows of stiches in each eye and stick the retina back on. They dont know what is causing it (not bungee jumping or a car accident) and everytime it happens my retina gets a little more cut up and i have all sorts of weird stripes through my vision.

      Now you my say.. "tough luck, you have bad eyes, live with it" but you see my whole life is based arround my eyes. I am a visual effects artist for the movies (lately 3d modeling on a movie about a ring) my eyes are my livilyhood.

      And so the chance that they are one step closer to being able to replace them matters more to me then anything i have heard all year.

      So if this is the "limited potential" you are talking about mr katz then i'm not really sorry for getting excited for nothing

      --

      -------
      Drink Coffee - Do Stupid Things Faster And With More Energy!
  8. How it's powered by martyb · · Score: 3, Interesting

    I was wondering how in the world it was powered. Come to find out, it's just a bunch of tiny solar cells according to
    this article at How Stuff Works.
    The light coming into the eye is focused on the retina. Solar cells convert light to electricity. Electricity stimulates optic nerves. Voila --Sight!

  9. Only for those who lost their sight by Hitokage_Nishino · · Score: 4, Informative

    There is an extremely interesting article in a recent Discover magazine about a man who was blind from the age of 2-3 recieving sight back in one eye thanks to stem cell implants.

    While after the operation he physically had 20/20 vision, he actually saw more along the lines of 20/500. The problem wasn't his eye, but his brain. He just hadn't learned how to fully percieve eyesight. One interesting note is that he does not perceive optical illusions. Since he's well past that critical stage of mental development when one is supposed to get it hardwired, he'll have a rough time getting his eyesight anywhere near normal. In fact, several other people who were blind as small children and had similar operations say they would rather be blind now.

    At any rate, while this will certainly be a great help to those who lost their sight as adults... it may not be of too much help to those born blind.

    1. Re:Only for those who lost their sight by Karen_Frito · · Score: 3, Insightful

      Perhaps not blind adults who lost sight as children -- but if this technology is developing sucessfully today ...

      Children NOW who lose their sight may never BECOME adults who lost their sight as children.

      Lose sight at 5, get chip at 6, return to normal life. (Extremly abridged version, minus all the "Learn to see again" stuff.)

      This is a wonderful innovation - even if its not for everyone, its a start. And everything has to start somewhere.

  10. More technical details by martyb · · Score: 4, Informative

    There's much more detail on the history, design, and development of the device in this EE times article. I was especially struck by how they persevered. They started on this in 1990 and things did not go entirely smoothly:

    "There were 50 to 75 major hurdles from the time we started," Vincent Chow said. "The biocompatibility side represented probably 40 percent of the issues. The other 60 percent were really in the electrical performance of our structures. That's because the final stimulation is an ionic stimulation. We're basically trying to interface a solar structure so that the microcurrents produced by the solar cell have a very high efficiency or functionality factor to stimulate the cells that are touching these particular areas."

    This version of the device contains about 3500 light detecting cells. If this version works out okay, they are planning to develop a much larger version of the chip.

    If the ASR chip is successful in restoring some degree of vision, Optobionics will make modifications to a final and significantly larger chip design. Some possible ideas, said Alan Chow, include placing openings in the chip to allow nourishment to flow between the outer and inner retina; and changing the direction of the electrical stimulation on an ongoing basis, a technique referred to as biphasic stimulation.

  11. Re:laser surgery.... by freeweed · · Score: 3, Interesting

    It's a common fallacy to think that 20/20 vision is "perfect", and that anything better is somehow "miraculous". There are many people with better than 20/20 vision. Hell, I used to be one, until I hit puberty and started wearing glasses - really freaked my mom out to be told that I had better than 20/20 vision. Made me feel a bit freakish, truth be told.

    Also keep in mind that "seeing something 20 feet away like it's 10 feet away" just means you might see a tiny bit more detail - at 20/20 vision most people can see damn near perfectly out to a LONG distance. Really makes me wonder why someone with 20/20 vision would risk their eyesight just for a marginal improvement.

    On this note, anyone remember WHY they chose 20/20 as the standard? Was it arbitrary?

    --
    Endless arguments over trivial contradictions in books written by ignorant savages to explain thunder in the dark.
  12. Re:Thank goodness by Anonymous Coward · · Score: 3, Interesting

    That there is no "blind-community" counterpart to the deaf-community

    Rather, there is no apparent blind community to those who are not directly involved with it.

    Having blind family members, I can say that there is actually a very large blind community, which I believe is necessary. It is important to realize that people with certain types of disabilities have different struggles and lifestyles then the general population, and being involved with others who share the same experiences can definately help in making life a little easier and pleasent.

    Also from my experience, people who have been blind from birth or early childhood would likely not chose to have an implant/surgery to correct the blindness for a few reasons.

    First, those adults who were blind from birth have areas in the brain responsible for sight that are not developed because they have never used them. If one of these people were to undergo a operation to correct the blindness, the person's brain would still not be able to interperet the stimulus in a coherent manner. They would see, but they wouldn't understand what they were seeing.

    Second (even if the first was not an issue), could you imagine viewing the world in a certain manner, and then one day, having all your preconceptions about everything shatter?

    People who have been blind from birth have never seen(duh!), but they do however have an understanding about seeing (ie. colors, patterns, etc.). This differs from the actual experience of seeing as we know it, and taking those concepts away would be tramatic. Most people would be unable to cope with this.

    Lastly, this is part of who the person is no matter how much it is disliked or how much of an inconvience it is. It is accepted, much like other things that (for the most part) cannot be changed. Having a hatred for something that is a piece of one's self, that cannot easily be changed, is unhealthy. So is having false dreams about "miracles" or "cures".

  13. As I just took a final over this... by PhilosopherKing · · Score: 3, Interesting

    Yes, 20/20 is mostly arbitrary. The neumerator denotes the distance (in feet) the test is given at. (Usually 10 feet, but they use a mirror to double the distance to the standard 20 feet.) The denominator denotes the distance (in feet) at which the critical feature of the letters/numbers/shapes subtends one minute of visual angle. (Is that not a A answer, I'll find out on Friday)

    --

    USA-Democracy is 270 million YESes and NOes a day, not one every four years.
  14. Talk about unthankfulness by xcomputer_man · · Score: 3, Funny

    From the article:

    "For another patient, though, the implant has been a bit sobering, Chow said. The patient, who has begun to recognize faces, was disappointed to see how his own face had aged."

    I can almost hear those doctors now. "Dude. You've been blind for many years, you were chosen to have your sight restored by a groundbreaking scientific process, and the only thing you can think about is how old you are?

    Get back on that operating table, I'm gonna yank that damn chip out your eye..."

  15. Reporting from ARVO by BWJones · · Score: 5, Insightful

    OK, I am one of the scientists here at ARVO (Association for Research and Vision in Ophthalmology), and was present at the presentation of Dr. Chow.

    I for one would love to believe in the results, but I have not seen any real scientific proof that these things work as advertised. While the video of patients was impressive and touching, there is very little hard science behind the development of the bionic retina and how it is integrating into the retinal environment. The only thing that everyone appears to be reporting on is that the chip is not rejected. And there are other more fundamental issues at work. For one, the silicon retinas require the equivalent of 3X's the brightness of the sun to activate the device and for realistic performace, they would require an external power source. The other issue is that the retinal circuitry that they are placing this bionic implant onto is severely degenerated and remodeled in these patients and may continue to degenerate further, thus complicating matters. That said, there is some indication that the surgery itself may cause some retinal rescue, not the implant. This is something they have not done control experiments on. Furthermore, the generation of low voltage current from the implant in the retina may be promoting retinal recovery of sorts while the silicon retina may not be doing anything for vision itself.

    We are still a looooong ways away from the idea of a bionic retina and I think that retinal implants will actually be the least effective method in the long run. Gene therapy, viral infective methods, stem cells, and post retinal bionics will probably work optimally sooner.

    --
    Visit Jonesblog and say hello.
  16. Sobering Thoughts by hyrdra · · Score: 3, Insightful

    Isn't amazing how fast technology moves? Remember Jordy from Star Trek? He used that big visor thing to restore his vision, and this is what writers thought would be the technology in the 24th century. Here we are in 2002, and we have a solar powered eye chip that can be implanted into the eye to give people some of their sight back, with no discomfort.

    Sure, it isn't perfect and it's only version .1 but as others have mentioned how long before this changes and version 4.0 is out with default 20/15 vision and zoom controls?

    Just step back and realize what an accomplishment this is and how fast technology changes everyday. It's almost scary to think what life will be like when I turn 60.

    Reminds me of something my Great Grandfather said: "I've seen the world come from stage coach to walking on the moon; nobody will ever lead that kind of life again."

    Well if this is the case I would think the rate of progression will disprove this. It's amazing to think we will all outlive the advancements that occured during his lifetime, but we probably will.

    This article just reaffirms that notion.

    --


    "I'll just chip in a bit for RedHat: I actually have that installed on my university machine." - Linus, '95
  17. Re:Full Article Text by Winged+Cat · · Score: 3, Funny

    I'd bet a sufficiently large Beowulf cluster of slashdot effects could take even Yahoo! down. ^_^