Strep Bacteria Resistant to New Antibiotic

Aaron Rowe writes "MSNBC and The Lancet medical journal have reported that the new oxazolidinone antibiotic Zyvox is ineffective against some forms of Staphylococcus aureus."

Comments

Re:Not a surprise

[!splut]

I'm afraid you are confusing the terms "anti-bacterial" and "antibiotic." Anti-bacterial is a very broad, vague term that can be applied to any substance or product that exhibits the ability to kill bacteria. It is a marketing buzzword, used to play on the consumer's fear of microbes and misunderstanding of microbiology. Rubbing alcohol, vinegar, and boiling water would all easily fit under the anti-bacterial label.

The products that you list - anti-bacterial cosmetics and soaps - kill microbes due to very high or low pH, alcohol content, the presence of detergents that lyse cell walls/membranes, and the presence of other toxic chemicals that kill a broad spectrum of organisms in a very general way - the same way bleach kills just about anything you dump it on.

But bleach, alcohol, detergents, etc, are NOT antibiotics. Antibiotics are drug-like compounds that kill bacteria in a targeted fashion, by interfering with growth, cell wall development, and/or metabolic pathways. Antibiotics bind to specific enzymes, proteins, or other structural molecules. Bacteria are able to gain resistance to antibiotics by accumulating changes in the structure of these molecules (via mutations).

So, nonspecific general anti-bacterial compounds, and NOT antibiotics, are present in these cosmetics and soaps. Microbes CANNOT easily develop resistance to nonspecific anti-bacterials. Thus, use of these anti-bacterial products has no effect on the evolution of antibiotic resistant strains of pathogens.

Interestingly, it should be noted that the formulation of many of these household anti-bacterial products is essentially identical to the forerunning "non-anti-bacterial" versions. All liquid hand soaps, for instance, are anti-bacterial to begin with. So the addition of the "anti-bacterial" buzzword on the bottle is just a marketing ploy.