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The Human Genome: More Viruses than Genes?

jmulvey writes "A new University of Georgia study shows that most of the human genome contains a huge historical record of retroviruses. The study adds to a growing body of evidence suggesting that viruses were instrumental in the evolution of chimps into humans."

55 of 118 comments (clear)

  1. Isn't old news? by SuperCal · · Score: 2

    Once again my post is going to sound like a troll when its not ment to,but isn't this old news. Now don't get me wrong I love UGA (Go Dawgs!), but I remember reading about this in high school. Maybe the story is that there is so much evidence, and not that its a new idea. End Ramble

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  2. chimps to humans? by HyperbolicParabaloid · · Score: 5, Informative

    Just a detail: humans are not theorized to have evolved form chimps. Rather, chimps and humans evolved from a common ancestor.

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    -------------------------
    A person of moderate zeal
    1. Re:chimps to humans? by R.Caley · · Score: 2, Interesting

      It depends on your POV. Some would class humans as a species of chimp, in which case the common ancestor would be a kind fo chimp too.

      --
      _O_
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    2. Re:chimps to humans? by suss · · Score: 4, Funny

      Just a detail: humans are not theorized to have evolved form chimps. Rather, chimps and humans evolved from a common ancestor.

      Well, the scientists are still not sure about Michael and JonKatz concerning that...

  3. Viruses Instrumental to Evolution? by $rtbl_this · · Score: 3, Funny

    Does this mean that Outlook will eventually evolve into a secure MUA?

    --
    "Are you being weird, or sarcastic?" said Emma. I said I didn't know because I get the two feelings mixed up.
    1. Re:Viruses Instrumental to Evolution? by macemoneta · · Score: 2

      Yes, and strangely enough, it's called Evolution. :-)

      --

      Can You Say Linux? I Knew That You Could.

  4. transposons by tid242 · · Score: 4, Informative
    i don't remember reading about much of the sort in high school, of course you very well could have attended HS more recently than i, or very very likely could have attended a school much better than mine, especially in the science department. but given the conservative nature of high school text driven, in no small part, by the boycotting nature of many 'christian-minded' institutions, i find the latter scenario more probable...

    anyway, the idea of latent viruses remaining in the genome is a rather old idea, most notably for transposons (aka 'jumping genes') which seem to randomly re-arrange themselves within the genomes and 'jump' from one part of a DNA strand to another... also, more recently the idea of viruses actually serving an advantageous purpose for humans has been put forth with the finding of the importance of transposon-like activity in specific instances, such as the HyperVariable region in B-cells (FYI the hypervariable region is a piece of DNA which eventually codes for the binding region of antibodies, which is important for making them recognize foriegn antigens (which will be highly random by nature))... but the point of this paper being that they are/were a driving force for evolution, specifically the evolution of homo which is an interesting, and to the best of my knowledge, new idea.

    -tid242

    --

    With a few exceptions, secrecy is deeply incompatible with democracy and with science. --Carl Sagan

    1. Re:transposons by PD · · Score: 3, Insightful

      Almost 150 years later, those drawings are still in most textbooks, cited as evidence for evolution.

      Let's get rid of *your* lie. The idea that embryonic development is evidence for evolution was abandoned by science a very long time ago. I can only believe that you either don't know any better, or you are deliberately making things up.

      Evolution is a fact, that's well established. All debate about evolution is about how it happened.

    2. Re:transposons by PD · · Score: 2

      And now, it's time to get rid of my own misunderstanding! (Yum crow is good)

      There are similarities in embryonic development that are shared by all creatures. The fact that the development is similar *can* be taken as a bit of evidence for evolution.

      So, my statement that science abandoned it a long time ago was wrong.

    3. Re:transposons by Suidae · · Score: 2

      http://inia.cls.org/~ae/Haeckels_embryos.htm

      "There appears to be no evidence that Haeckel was ever tried for fraud in the Jena university court, much less that he was convicted of it."

      His contemporaries did call him on the inaccuracies in his drawings, and no doubt he was accused of fraud, but he was never 'tried and convicted' of it.

      If you are going to espouse accuracy in textbooks, perhaps you should check the accuracy of your posts.

      It is good to see that at least some textbook makers are replacing these widely used drawings.

    4. Re:transposons by young-earth · · Score: 2, Interesting

      I'm very glad you agree that it has been abandoned by responsible scientists. However I think you'd best get educated on what is in the textbooks. In the last two years major college intro bio textbooks have been published and are in heavy use, textbooks that still contain Haeckel's drawings. Do you need the ISBN's for them?

    5. Re:transposons by PD · · Score: 2

      Check my other message. Comparitive embryology is considered evidence of evolution. Haeckel's embryos are not regarded as accurate. Modern comparitive embryology ignores Haeckel's drawings, and they do not deserve to be included in books.

      Also, are you sure that the drawings in the textbooks are the ones done by Haeckel, or are they more modern?

    6. Re:transposons by AJWM · · Score: 2

      Well, ontogeny may or may not recapitulate phylogeny -- but that first cup of coffee sure does.

      --
      -- Alastair
    7. Re:transposons by PD · · Score: 2

      Gravity is only a theory. So are we justified in thinking that we could just float away from the surface of the earth?

      The word "theory" means an idea that has the heavy and full support of fact and observation.

      And no, evolution is not a theory, it's a fact. The Theory of Evolution by Natural Selection is the thing that attempts to explain the fact of evolution.

    8. Re:transposons by Tackhead · · Score: 2
      > Well, ontogeny may or may not recapitulate phylogeny -- but that first cup of coffee sure does.

      Which reminds me of the other time I've seen someone use the issue of ontogeny recapitulating phylogeny while trolling... baiting.org's wonderful troll of Darwinism and Broken Translators.

    9. Re: transposons by Black+Parrot · · Score: 2


      > The scientific method is really bad at proving things. It's good at disproving things however.

      And cutting to the chase, it disproved any literal interpretation of Genesis something like 200 years ago - before anyone had ever heard of the theory of evolution. In the unlikely event that anyone ever disproves the theory of evolution, creationists will merely be back where they were in 1858: already disproven by basic geology. Since then we've added disproofs from biology, cosmology, planetology, archaeology, and probably several other independent fields of enquiry.

      The biggest sign of the rampant ignorance in the creationist camp is that they think it would actually help their position even if they refuted evolution honestly.

      --
      Sheesh, evil *and* a jerk. -- Jade
  5. in the same way by tps12 · · Score: 2, Funny

    Computer viruses have been instrumental in the evolution of MS Windows.

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    Karma: Good (despite my invention of the Karma: sig)
  6. Re:Book written on this by orthogonal · · Score: 3, Informative

    no.

    Darwin's Radio is a poor book with a purely bogus concept of what evolution is.

    The central conceit of the book is that the evolution from Neanderthal to human was designed into the genome, in the 'junk' DNA, and set to express itself at some pre-set (designed) time. The story revolves around a further designed evolution from human to a new (and presumably 'better') species.

    The central point is that the 'junk' is designed. That's not evolution, but some variant of creationism. It's also implausible crap.

    Taken purely as art, the book isn't much good either -- the basic plot is that the evolution of the 'over-man' will occasion much Fear, Uncertainty and Doubt. It's not worth wasting time on.

  7. Re:Book written on this by Bonker · · Score: 3, Funny

    Damn, and there I thought I had a good idea for a Sci-fi story until I read this and found that someone had already beat me to it.

    Still, it's an interesting idea to contemplate:

    Aliens/Deities come down and notice some pre-hominid primates.

    "Boy, these guys got potential, but not a lot. Why don't we KICK 'EM UP A NOTCH! BAM!"

    Okay, sorry. I should be shot for the gratuitous catch phrase.

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  8. Re:obviously by Accelerated+Joe · · Score: 2
    I'm usually not opposed to mass-marketing scientific information by filtering it so that more people can reasonably understand it, but evolution is a clear exception for me.

    My wife used to teach a high school science class, and many of the students (many of whom were admittedly biased against learning evolution because of their religious parents) had such a mass media education in this field that they couldn't separate the "obvious" truth from the mass-marketed "truth". So, in this case, the misinformation that is spread is possibly misleading generations of people. And just think about the impact on those who have never taken a science class, but regularly vote, for instance.

    I think it would be in everybody's best interest if they would drop this metaphor in favor of the truth.

    --
    They who would give up an essential liberty for temporary security, deserve neither liberty or security
  9. This prooves it! by Mt._Honkey · · Score: 2

    Humans are biological weapons put on earth to infect each other!

    Oh wait...

    --

    Don't Bogart the fish sticks
  10. At the moment the best-known retrovirus is HIV by dpilot · · Score: 3, Interesting

    So what is HIV doing to human evolution?

    * In the Darwin's Radio sense, perhaps our genes have looked at our actions, and decided, "It's time for us to go."

    * In a punctuated equillibrium sense, I've always heard that evolution through natural selection *really* kicks in when you have 90%-type mortalities. Do we know for sure that the death rate from AIDS is 100%? How about the "sufficient to procreate" rate? Left completely unchecked, would AIDS kill off the human race, or would a tiny fraction of us evolve past it, and their descendents inherit the Earth?

    --
    The living have better things to do than to continue hating the dead.
    1. Re:At the moment the best-known retrovirus is HIV by zenyu · · Score: 3, Interesting

      So what is HIV doing to human evolution?

      One of our characteristics as humans is that we try to assign narratives to everything. This is a great thing because it forces us to come up with theories and then through discussion refine them. But sometimes there isn't a reason, as with random processes like evolution. You didn't say there was a reason for HIV, so I won't belabor the point.

      It's still a good question, it looks like it has redirected some of the hive's mind to figuring out retro-viruses and also to figuring out biological data storage and manufacturing devices (DNA & RNA). This is probably better use of medical researchers than a random trial and error attack on cancer.

      As far as biological evolution, this will happen to an extent. But not so much really, remember the plague, black death? Well less than 5% of Europeans has any immunity. We discovered hand washing and rat control before it really reworked the genome. Condoms and medicine will do the same for HIV.

      Many large cats do have a HIV like virus that once decimated their population and for the last 100,000 years have evolved to fight it off, though with a dimished life span. We're not gonna wait that long for a solution...

    2. Re:At the moment the best-known retrovirus is HIV by dpilot · · Score: 3, Interesting

      > But sometimes there isn't a reason, as with random processes like evolution. You didn't say there was a reason for HIV, so I won't belabor the point.

      I wasn't attempting to assign or invoke any sort of reason, only wondering about long-term effects. Even though I later mentioned Darwin's Radio I wasn't meaning to wander out on that branch.

      > We discovered hand washing and rat control before it really reworked the genome. Condoms and medicine will do the same for HIV.

      So maybe HIV will really alter our perception and application of religion and some political systems. Right now it appears that religious conservatism is the greatest obstacle proper education about sex and HIV risks, and promoting the use of condoms. South Africa has the highest proportion of AIDS, and at least part of the reason is/was political. The government set up a situation with residence in one area, and jobs in another. Workers were on a weekly/monthly commute, and AIDS spread like wildfire through the prostitutes.

      So maybe religious and political opinions will need to be the biggest changes.

      > We're not gonna wait that long for a solution...

      I have an ugly feeling that at some point, social-unrest-driven solutions are going to be forced on us, and some of them will be decidedly sub-optimal. Unfortunately, we had time to develop better solutions, and squandered it because of religious/political reasons.

      --
      The living have better things to do than to continue hating the dead.
    3. Re:At the moment the best-known retrovirus is HIV by a_d_white · · Score: 2, Informative

      I've always heard that evolution through natural selection *really* kicks in when you have 90%-type mortalities. Do we know for sure that the death rate from AIDS is 100%?

      The mortality rate for AIDS (90% vs. 100%) is not issue. For natural selection to be a strong force, it matters how many people in the population are effected by AIDS compared to the frequency of a gene for immunity. If only 5% of the population is immune to AIDS, but <5% of the population has HIV, natural selection won't be strong enough to favor the gene for immunity.

    4. Re:At the moment the best-known retrovirus is HIV by Alsee · · Score: 2

      most effective AIDS control possible (abstinence)

      Considering that abstinence has a failure rate approaching 100% I wouldn't consider it particularly effective.

      -

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  11. This is good news. by Mt._Honkey · · Score: 3

    If you haven't, read the article. It says that these retroviruses have been a significant driving force for evolution.

    Some people claim that evolution has stopped in humans, but this shows us that maybe it hasn't. Maybe through more retroviruses getting into the system, and this "giant game of chess" being played in our DNA, we will continue to evolve. For better or for worse, I don't know, but I see it as a major chance for improvement.

    --

    Don't Bogart the fish sticks
    1. Re:This is good news. by Alsee · · Score: 2

      key component to evolution is "selective pressure"
      Yes.

      so that poor genes kill you off before you breed
      Not necessary.

      Do some people die for various reasons before having children? Yes.
      Are any of these causes of death influenced by their genes? Yes.

      Do some people have more children than others? Yes.
      Is this influenced by their genes? Yes.

      Evolution still occurs. Sometimes it is just more subtle than starvation due to physical defect.

      -

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      - - You can't take something off the Internet! That's like trying to take pee out of a swimming pool.
    2. Re:This is good news. by Mt._Honkey · · Score: 2
      I don't know if that was a troll or not, but I'm going to respond anyway.

      First, what makes you think that more people are becoming gay? And second, that can't be an evolutionary change. IF homosexuality is geneticly determined, it seems to me that it would be quickly rooted out and would vanish inside a generation. Why? Becuase gay people don't have kids (well, the vast majority). In order for a genetic alteration to stick around, the carrier has to reproduce.

      In ancient Greece, homosexuality was encouraged, because it kept you a 'technical' virgin. A HUGE chunk of the population became homosexual. Whether or not they stayed that way their whole lives, I don't know.
      Will be an interresting population to look at to verify if natural selection still exists for humans
      Uh... how could it not in this case. Since they don't have kids, they don't pass on any genes (even your hypothetical "gay" gene), so it ends. I think that this simple fact is a good argument against homosexuality being genetic.

      Mandatory quote form Hot Shots Part Deux:
      They've taken a vow of celebecy, like their fathers before them...
      --

      Don't Bogart the fish sticks
  12. Re:Retroviruses, Open Source, and Cancer by airuck · · Score: 2, Funny


    "So, what you're saying is that open-source is helping to cure cancer in the same way that the pencils the scientists are using are helping to save cancer."

    Let's review your syllogism:

    A pencil is a tool.
    Clinical research generated at a cost of billions and shared in an open and standard fashion is a tool.
    Proven algorithms are tools.

    Therefore, open source bioinformatics data and tools have the same worth as a pencil.

    You remind me of Steve Martin's routine "How to turn a fortune in real estate into $25 in cash!", but he was being funny as a jerk.
    It is unfortunate that some people were given brains when a spinal chord would suffice. - Albert Einstein

    --
    First entomology, then virology, and finally bioinformatics systems. Bugs follow me wherever I go.
  13. Mitochondria by quantaman · · Score: 2

    Okay, IANAB (I am not a biologist) The mitochondria (essentially the power plants of our cells) were actually an origionally independent life form. Sometime very early in our evolution they found themselves inside our cells and have been integrated in as a necessary part. I could be mistaken but I believe they are essentially inherited purely from the mother as they just stick with the egg and the number coming in with the sperm is trivial. They also have their own DNA.

    --
    I stole this Sig
  14. interesting by Transcendent · · Score: 2

    It is interesting, this step of evolution.

    If you have ever seen the matrix, and caught the ramble of one of the agents about how humans are a virus, spreading out and distroying the earth for it's own good.... it is true. And now to think (although this isn't a new and fresh idea) that humans took that step because of a virus... could some of the disposition of that virus or any virus effect our behavior?

  15. Re: Evolution??? by Black+Parrot · · Score: 2


    > It goes against the first and second laws of thermo-dynamics

    This has never been demonstrated, or even argued well, in spite of the fact that creationists have been appealing to it for decades. (Quick, taftman - can you even tell us what units are relevant to the 2LoT without looking it up? Hint: it it's a law of thermodynamics. It doesn't say a heck of a lot about speciation.)

    > and is still a theory

    As is atomic theory and electromagnetic theory and the theory of gravity and the theory of relativity and all the other big stuff that gives shape to our knowledge in the empirical sciences. Don't confuse a scientific theory with the conversational use of the term as a synonym for "wild ass guess". "Theory" is as high as you can go in the empirical sciences; once a theory, always a theory - unless refuted. So yes, the theory of evolution is still a theory, since no one has come close to refuting it. (Indeed, the supporting evidence keeps pouring in.)

    > and unproven

    We don't prove things in the empirical sciences. (As the saying goes, "Proof is for mathematicians, alchohol, and gunpowder.")

    > in these hundred or so years since its inception.

    143 years since the first publication on the topic, if I subtract correctly. That's 143 years of continual attempts by creationists to refute it, but instead of going away it is now better established than ever.

    You may want to get yourself a bit better informed on these topics before posting on them again, if you don't like to come off sounding like a fool in public.

    --
    Sheesh, evil *and* a jerk. -- Jade
  16. Re:Darwin's Radio by Greg Bear? by AJWM · · Score: 2

    If the science in it is as silly as that in Bear's "Blood Music", I'll give it a pass, thanks.

    --
    -- Alastair
  17. Re:Book written on this by AJWM · · Score: 2

    I'll pass. Sounds like it bears as much relation to real biology as Star Trek does to real physics. Lots of nice buzz phrases that sound like they might make sense, but totally meaningless in actuality.

    (Not that that can't make for a good story if you're willing to suspend disbelief, a lot of folks like Greg's writing -- it's just his style tends not to match my taste.)

    --
    -- Alastair
  18. Re:Evolution??? by t · · Score: 2
    How could they all have possibly developed the same organs, eyes, brain etc etc...AND have totally interchangable DNA...
    The amount of time it takes to evolve things suchs as eyes is extraordinarly large compared to the amount of time it took humans to develop means of moving around.

    And also, you should look up what a mule is. You would be suprised at how different two things can be and still produce offspring. (sterile in this case but amazing nonetheless.)

    mule -- (sterile offspring of a male donkey and a female horse)

    t.

  19. Re:Evolution??? by t · · Score: 3, Funny
    wow you missed that point completely. Lets use some logic shall we? First of all, it is pretty damn hard to travel around without eyes. Therefore it would not be a silly expectation that the eyes developed long before humans started globe trotting. Hence the quite reasonable expectation that people have the same type of eyes. (Not that they are exactly the same, color varies widely for example.)

    And different races do not end up in the same place by chance. When people live in an area long enough, certain changes are quite common in order to better cope with the environment. Skin color is one of those.

    The purpose of the mule example, which you did not even bother to research at all, is that they exist at all considering their parents have differening dna lengths. And no, a mule is NOT a mutation, merely an offspring, an unsuccessful offspring, which is NOT uncommon in evolution. Evolution is NOT a direct path to success. Evolution is trial and error. The mule is an error obviously since it is sterile.

    Look, it is obvious that you know very little about what you are claiming is bunk. If you truly wish to argue against something then you must know more about the material then the people you are arguing with. That does not mean you have to believe it, but merely that you know it.

    sinfully yours, t.

  20. Re:Evolution??? by PD · · Score: 2

    We're not in a closed system. That's where your thinking is going wrong, and that's why the second law doesn't apply.

    Also, entropy is a global value. Locally, entropy doesn't have to always increase. That's why it's possible for you to pile up bricks and call it a wall. If entropy always increased, then you wouldn't be able to build a house!

  21. Re: Evolution??? by Black+Parrot · · Score: 2


    > As I understand it, its the law of gravity, but I may be wrong, i'm no scientist.

    If by "it" you mean the 2LoT, then no, it's about limits on our ability to extract useful work from heat. Since you say you're no scientist, please be informed that the 2LoT tells us nothing useful about evolution, and the people you heard that argument from don't understand it any more than you do. You would do well to get your information from more reliable sources, such as college textbooks.

    > We are both seeking truth, I am coming from the faith and biblical angle, and you are coming from the humanist angle and science is our common element.

    Actually, I'm coming from the angle that evidence trumps tradition. That has nothing to do with humanism.

    Also, science is not our common element. You have been misinformed by people who use pseudoscientific claims to validate their beliefs, but it isn't science. (I suspect that most of them do it from ignorance rather than mendacity, simply repeating what they've heard their own authority figures say. But dressing myth up in scientific jargon doesn't make it true.)

    I'm sorry if I gave offense. Please understand that I am quite offended by people trying to use pseudoscience to justify teaching their religion in public schools, and I am going to refute it everywhere I see it.

    --
    Sheesh, evil *and* a jerk. -- Jade
  22. Half Human, Half Virus by m_evanchik · · Score: 2

    A lot of human illnesses stem from our close proximity to animals. If I recall, the flu virus is supposed to have originally affected horses (or is it pigs? it doesn't matter for the example), and then the virus eventually evolved to affect humans, because we were always around the horses, and presented an opportunity for the virus to adapt to a new enviroment (us).

    Your mentioning the feline "HIV" makes me wonder if maybe the AIDS shouldn't be blamed on monkeys, but on cats.

    On an unrelated note, I've often wondered if there are any viruses out there that are good for us, sort of like the symbiotic bacteria in our stomaches that help us digest, and that help yogurt marketeers. Instead of making one sick, wouldn't it be cool if there was a virus you could catch that made you healthier.

    And as a side note, I believe most people ,myself included, are mischaracterizing the nature of viruses affect on evolution as explained by the researchers. It's not that the viruses cause any benign change per se, but that the body mutates to defend against them, thus increasing complexity of the organism.

    Weird stuff when you consider that this is delving into the nature of life itself.

    What am I, half French, half Russian, one quarter virus? (Yes that adds up to more than one, they're not mutually exclusive sets.)

    And it's kind of interesting that people aren't talking about the ramifications of this idea regarding computer viruses.

    Does the existance of computer viruses ultimately benefit us, by forcing the development (in this case entirely conscious, as opposed to biological evolution) of more complex computer systems.

    1. Re:Half Human, Half Virus by MountainLogic · · Score: 2
      On an unrelated note, I've often wondered if there are any viruses out there that are good for us

      It has often been speculated that mitrocondria, the "energy factories" of the cell are in fact symbiotes. Mitrocondria even have their own DNA.

    2. Re:Half Human, Half Virus by hoggoth · · Score: 2

      > It has often been speculated that mitrocondria, the "energy factories" of the cell are in fact symbiotes. Mitrocondria even have their own DNA

      It has also been speculated that Midichlorians, which create a different kind of energy, are also symbiotes.

      Not to mention a lame cop-out explanation that ruined a once-interesting spiritual component to the Force.

      --
      - For the complete works of Shakespeare: cat /dev/random (may take some time)
  23. HIV causes AIDS a myth? by solferino · · Score: 2, Interesting

    a link to some material on whether the widely-spread convention that there is a retrovirus called HIV that causes AIDS is true.

    a quote from that site :

    "If there is evidence that HIV causes AIDS, there should be scientific documents which either singly or collectively demonstrate that fact, at least with a high probability. There is no such document."

    Dr. Kary Mullis, Biochemist, 1993 Nobel Prize for Chemistry.

    this page on the site links to the best introductory articles on the 'virus myth'

    an excerpt from one of the articles on the site

    The response to the first major critique of the HIV theory, by Dr Peter Duesberg, professor of molecular biology at the University of California at Berkeley, was bewilderment, followed by fury. Duesberg had been voted Californian Scientist of the Year for his discoveries in the field of retroviruses (of which HIV is supposed to be one). He argued in 1987 that HIV could not be doing the damage attributed to it, because it was so difficult to find in the body, even in a person dying of AIDS. He postulated that an explosion in the use of recreational drugs during the 1970s was probably the main cause of AIDS. He was first ignored and then pilloried for persisting with his views. He lost a $ 350,000 "outstanding investigator" award and became an embarrassment to his university, which, while unable to fire him, reduced him to chairing its annual picnic committee.

    The past 10 years have shown Duesberg to have been right on several counts. He stated that HIV could not kill immune cells, that AIDS would not become a heterosexual epidemic and that the anti-viral drug AZT would kill rather than cure. On all three issues, the evidence has gone his way.

    note to moderators : please note that the assertions against the conventional thinking on HIV -> AIDS are being made by respected scientists as shown in the above two excerpts. This comment is not made as flamebait or as a troll. The ideal of science is informed debate, not willful dismissal of dissenting opinion.

  24. Duesberg & questionable science by Lurkingrue · · Score: 2, Informative

    You bring up an interesting point, but its pretty well established that Duesberg & other "non-retroviral" theorists are wrong on many counts here.

    First of all, Duesberg's claim that "poverty, malnutrition and parasitic and tropical diseases" cause AIDS in third world populations, while "recreational drugs, irradiation and AZT" and nutrition are responsible for the syndrome in the Western world are patently false -- disproven repeatedly. AZT and other anti-retrovirals have been shown to increase lifespan and decrease symptomatology in AIDS patients. HIV is a heterosexual epidemic in many places, and viral loads do seem to correlate with diminished T-cell numbers.

    Other "non-viral" theories of AIDS put forth, such as Papadopoulos-Eleopoulos' "oxidizing agent" theory have been equally disproven. It seems that, if there is an viable, alternative theory to the retroviral HIV of AIDS, nobody has presented it yet.

    Secondly, it would be very difficult to demonstrate that the retroviral HIV theory of AIDS completely fulfills all the requirements of Koch's postulate in a human model (in fact, it would be an immoral and unethical act to test it this way), but the evidence is pretty strong in the support of it. People who show no evidence of HIV do not have AIDS (although similar syndromes exist). As far as I know, all people with AIDS have been shown to have HIV infection. Furthermore, people who have had AIDS and have begun antiretroviral therapy have shown dramatic regression of symptoms, while no other therapies (directed or not) seem to be effective.

    The "non-viral" people -- Duesberg supporters in particular -- tend to argue against strawmen, using old data, and demanding that the HIV camp disprove negatives.

    1. Re:Duesberg & questionable science by solferino · · Score: 2

      Well my parent comment has already been modded down, so my hopes for an intelligent discussion of whether HIV exists and causes AIDS seem to be rapidly diminishing.

      Thankyou for your even-toned reply. However, I do not agree with your line of reasoning. You essentially seem to be saying that the HIV theory dissident's claims have been disproven. You state this without mentioning or linking to any papers along these lines. From my point of view the dissidents seem to have been ignored rather than defeated.

      Further, it seems to me that the burden of proof lies with the proponents of the HIV causes AIDS theory. This is the general nature of scientific debate - to substantiate a positive claim against negative (sceptical) arguments rather than the other way around.

      Finally there are now a large number of members of the scientific community expressing some level of scepticism about the HIV causes AIDS hypothesis. Some of the major dissidents include :

      Dr. Robert Root-Bernstein, who held a MacArthur Prize fellowship from 1981 to 1986, is associate professor of physiology at Michigan State University

      Dr. Gordon Stewart is professor emeritus of public health at Glasgow University, and a former WHO adviser on AIDS.

      Dr. Alfred Hässig, (1921-1999) was professor emeritus in immunology at the University of Bern, Director of the Swiss Red Cross Transfusion Service, and President of the Board of Trustees of the International Society of Blood Transfusion. With colleagues he formed the Study Group for Nutrition and Immunity.

      Dr. Richard Strohman is professor emeritus in molecular and cell biology at the University of California, Berkeley.

      Dr. Etienne de Harven is emeritus professor of pathology, University of Toronto. He worked in electron microscopy primarily on the ultrastructure of retroviruses throughout his professional career of 25 years at the Sloan Kettering Institute in New York and 13 years at the University of Toronto.

      Dr. Joseph Sonnabend, a New York physician and one of the first AIDS researchers, has been questioning the HIV-AIDS hypothesis.

      The German virologist Dr. Stefan Lanka.

      (excerpted from the whistleblowers page on the virus myth website)

      Further, here is a petition questioning the basis of the HIV hypothesis - the present number of signatures is more than 5500 - you can view the list and see that many of these people are established scientists.

      To me it seems very strange that people from within the scientific establishment would be questioning common dogma and risking a great deal of mainstream credibility and their own financial security without their holding a genuinely sceptical position - it comes down to a question of motive and i can see no other reason for such people to 'stand out in the cold' except for a personal motivation to uphold rigour and independent thinking in science

  25. Re: Evolution??? by Black+Parrot · · Score: 2


    > Evolution is akin to a tornado hitting a junkyard and creating a fully functional 737

    No, evolution is more like a genetic algorithm that slowly refines a solution that does not conform to any human design at all.

    > these are the kinds of trial and error odds we are talking about.

    No, not at all. Evolution usually works by very small tweaks, which accumulate over time. Probability arguments are irrelevant because (a) there's not "correct" target to calculate the odds of hitting - anything that survives will do, and (b) the odds of different outcomes are not at all uniform, partly because life is based mostly on chemistry, which definitely plays according to rules rather than absolute randomness, and partly because whatever randomness the chemistry does produce is passed through a filter - natural selection - which greatly biases the distribution of the mutations that get passed on to the next generation.

    If you want to debate the theory of evolution you have to start by understanding it, and if you want to understand it you have to start by realizing that it is nothing like human design processes.

    --
    Sheesh, evil *and* a jerk. -- Jade
  26. Re: Evolution??? by Black+Parrot · · Score: 2


    > A mule is a mutation, the fact that its sterile and that there NEVER has been a good mutation is more evidence against the evolution theory.

    Actually, a mule is the product of mating two species that have diverged so much that the chances of having a fertile offspring between them is extremely small, but have not diverged so much as to make a viable offspring unlikely.

    IOW, mules are exactly the kind of thing you expect from the theory of evolution. As usual, even the tiniest knowledge of biology stands the creationist argument on its head.

    > One more thing, as I understand it we have more in common with frogs and pigs genetically than we do with apes anyway.

    Not so. You need to start getting your "facts" from more reliable sources.

    --
    Sheesh, evil *and* a jerk. -- Jade
  27. Re:obviously by Planesdragon · · Score: 2

    A suggestion:

    Evolution is breeding. As in, breeding programs. As in, something that we've done with horses, wolves, and bunny rabbits. And the bunny rabbit breeding can be done at a school relatively easily.

    The only real difference is that in breeding the traits that humans like are the ones that are brought out, but in the wild the traits that allow a creature to best survive (eat/mate/breed/notgetkilled) are brought out.

    _HISTORICAL_ evolution is the only thing that religion can possibly have a problem with--and by splitting the two, you can ignore the religous debate and focus on learning science.

    (A good short rebuttal to "God created the universe, so you're wrong" might be "if the universe was created, it was created looking a lot older than it is, probably so we could learn about how it would act for the next X years.")

  28. Re: Evolution??? by Black+Parrot · · Score: 2


    > Why would a creator feel the need to come up with unique ways of doing the same things for all organisms?

    Unfortunately, that convenience is a blow against creationism as a scientific explanation. As I said last time this topic came up, creationism is a wildcard explanation:

    Two animals are similar? God re-used the design! Two animals are different? God decided not to re-use the design!
    Wildcard explanations are useless to science because they don't really explain anything at all. A good theory makes testable predictions, or at least tells you where to look to find more interesting stuff. But the creationists' knee-jerk "Goddidit" explanation for everything tells you there's nothing more to see. It's a recipe for ignorance, not for science.
    --
    Sheesh, evil *and* a jerk. -- Jade
  29. Re:Evolution??? by Black+Parrot · · Score: 2


    > Evolution teaches that life increases in complexity, and therefore defies the second law.

    Actually, the 2LoT doesn't say anything about complexity at all. Look up the units used in the formula that expresses the 2LoT, and let us know if you can explain how a quantity with those units is relevant to biological evolution. (Or about complexity, for that matter.)

    Also, for a purely intuitive notion of complexity like you're working with, genetic algorithms produce it all the time. I know people who produce amazing things with genetic algorithms, turning piles or random numbers into the controllers for intelligent agents. The 2LoT doesn't interfere in the least.

    --
    Sheesh, evil *and* a jerk. -- Jade
  30. Re:A rational discussion by solferino · · Score: 2

    well i notice from the amber light next to yr name that i have now made yr lists of foes - the first time anyone on slashdot has made me one - that's fine by me, and of course you have the right to do so, however you seem by yr action to be continuing the long held practice of ignoring dissent on the HIV causes AIDS hypothesis - i.e. by my speaking out i am now on yr ignore list

    thankyou for linking to a paper - i will have a look at it - however i do not feel i have the expertise necessary to judge it's validity - and this is why i listed the names of some fairly respected scientists in my previous comment - these are obviously people who do have the expertise and who are questioning the hypothesis - however i have never heard this mentioned in the mainstream media - like you, the media have set their filters to 'ignore' - their dissent may or may not be good science - but why is the dissent not even acknowledged? - very few people even know that there is dissent from credible scientists on this issue and this is what i wanted to bring to people's attention by my post

    the website i linked to in my first post has a large repository of scientific papers contesting the HIV->AIDS hypothesis including at least one paper for every name that i listed in my second post - they are all easily accesible from the whistleblowers page from which i excerpted my list - i imagined that people would go directly to the source rather than expect me to try to paraphrase their arguments - i wonder whether you yrself visited the site?

    in relation to the list of 5500 names - these are listed prominently on the major HIV->AIDS dissident page on the web - I would imagine that legal action would have quickly ensured removal of the names of any people who were being wrongly touted as sceptics of the HIV->AIDS hypothesis

    my position on the HIV->AIDS hypothesis is simply a sceptical one - in the late 70's and early 80's a syndrome was documented as aquired immune deficiency syndrome - several years later an assertion was put forward that a retrovirus had been found and was the cause of the syndrome - the website i linked to has the papers of highly eminent people questioning both of these claims - science is all about questioning 'common sense' assumptions - so why have these people been continually left out of the debate? - indeed there has been no debate as mostly they have struggled to be published or have coverage in the mainstream media

    i wish you luck in a medical profession that due to massive abuse of power and an increasingly marked desire to enter the pay of the drug companies is rapidly losing the trust and confidence of the common people

    finally i'll end with a quote from a fellow named hippocrates - he doesn't seem to have much to say about whether HIV causes AIDS or not - but he does seem to have some commentary on the course that the mainstream medical community has followed in treating the syndrome :

    I will follow that system of regimen which, according to my ability and judgment, I consider for the benefit of my patients, and abstain from whatever is deleterious and mischievous. I will give no deadly medicine to any one if asked, nor suggest any such counsel;
  31. tim teeter registered nurse by solferino · · Score: 2

    ok i've now had a brief look at the paper you linked to - it's by tim teeter RN (RN = registered nurse) - is this really the best you can do? - i give you papers by people with 20+ years in the exact field of virology or nobel scientists in related fields and you come back with a paper by a registered nurse?!! - furthermore not even a disinterested party but a member of the AIDS lobby group - i quote - Tim Teeter is Associate Director of Treatment Support and Publications at the San Francisco AIDS Foundation. - my scepticism only grows...

    ok some brief responses to material from the paper

    AIDS is defined by the Centers for Disease Control and Prevention (CDC) as the presence of a positive HIV antibody test and one or more of the illnesses known as opportunistic infections (OIs) or a CD4 cell count below 200 cells/mm3.

    so even though AIDS was on the scene first it appears to have now been redefined to include a positive result to the 'HIV antibody test' - summary : something is documented as Acquired Immunde Deficiency Syndrome - a hypothesis is put forward that this is caused by something called HIV amd all dissenting opinion is crushed - the originally defined AIDS is redefined in terms of the later 'discovered' HIV - isn't this a gross breach of empiricism?

    this is the very first sentence - however two paragraphs down the author flatly contradicts his own definition of AIDS i.e. requiring a positive result to the 'HIV' test

    The vast majority of people with AIDS in resource-poor countries have not had an HIV antibody test; even in developed countries, not all people with AIDS have had viral load tests. Those who have had viral load tests showing nondetectable virus generally have no additional tests to confirm the presence of HIV genetic material.

    i won't go on - as i said before the burden of proof is on the originators of a theory and not on the sceptics - this paper you've given me is doing a very bad job of convincing me with major logical inconsitencies in it's first three paragraphs

  32. Re:A rational discussion by solferino · · Score: 2

    in response to yr point 2

    Its not that the scientific community ignored Duesberg's and other views on AIDS, nor were they left out of the debate.

    well my experience and those of the general public around me is that they were left out of the debate - despite being a sceptic from the early days of the AIDS story i had never heard that emminent scientists were also sceptical of the theory through the mainstream media - it was never reported - even now with the fact of the president of south africa's scepticism difficult to ignore, media reports on the president's stance never in my experience mention support from major western scientists - i only discovered the virus myth page after hearing an interview with eleni papadopoulos on an independent community radio station and then doing a web search on her name

    i can imagine the mainstream media's rationalisation of this blackout goes something like this - there's this awful thing called AIDS, some of our clever scientists tell us that it's caused by a retrovirus they call HIV - some other clever scientists are indicating some sceptisism about HIV being the cause of AIDS - but really we can't report this because it's going to be hard enough to get the great unwashed public to perform safe sex and if we let them know that there's some doubt in the scientific community then our message will not be listened to

    maybe you agree with this rationalisation - i certainly do not as it is not how science is meant to be done - and risks the danger that a truly massive crime against humanity may have been practised by feeding people highly toxic drugs on the basis of a flawed hypothesis that was not allowed to be examined with due scientific rigour - you do not seem to appear to realise that instead of a proper scientific culture we live in what could better be described as a 'church of science' culture where scientific dogma is handed down from on high and the media blindly parrots this dogma from the established 'experts'

    with respect to your 3rd point - i do not keep on bringing up the 5500 names - i simply responded to a query in yr reply, rather than bringing it up again independently - now as to your assertion that the names may be false i find this rather implausible as it would be giving the other camp a very big stick with which to be beaten as the names are easily checked - i myself just did a web search on three of the names i randomly extracted from the top of the list - they are :

    Steven Jonas, M.D.
    Hansueli Albonico, M.D.
    Sungchul Ji, Ph.D.

    all three returned numerous hits from google searches relevant to them being experts in the AIDS domain of knowledge - please check for yrself - again i assert that if their names were being used without their permission they would rapidly have been withdrawn from the site and/or the website's owners heavily sued

    you do not seem to understand my reason for using these people's names as i have previously explained it - it goes back to a policeman's logic - understanding people's motives - in a world where vast amounts of funding and prestige are given to members of the scientific and medical establishment who subscribe to the established theory it makes little sense for members of this same community to attack the conventional thinking - if a large number are doing so then this suggests to me that there may indeed be some substance behind their claims - it does not convince me, nor should it convince others, however it should serve to inculcate some level of scepticism in people with non-expertise if it is allowed to be reported

    further on this point i find your assertion that people showing dissenting opinions will be showered with money highly naive or disingenuous in the extreme - look at the example of peter duesberg which i quoted in my first comment who had exactly the opposite experience

    finally on point four i did not quote the whole oath in full - i quoted the part that seems readily ignored by the medical establishment and yet to me still seems to be a very noble and necessary ideal to hold on to - the idea of 'first, do no harm' - and yes i do consider chemotherapy 'deadly medicine' - how could anyone not?

  33. Re:A rational discussion by Lurkingrue · · Score: 2, Interesting

    1) Duesberg was listened to, and his ideas were proven wrong. His statements on HIV and AIDS causation have almost universally been shown to be false. He has not been "showered with money" or given media attention because his theories on AIDS are repeatedly proven incorrect.

    2) When AIDS was initially reported, there was plenty of confusion in the media. People were linking it to being Haitian, with being gay, with living on the coasts of the US...and a dozen other things.

    3) None of the people you mentioned seem to have anything to do with AIDS research. None of them has anything published in medical journals about such research. They don't appear to have training in areas like molecular biology or virology (one is a semiotician and a toxicologist!?!). They seem to have no stated theories on why AIDS takes place, or why HIV could not be the causative agent for AIDS. I have no reason to think they are "experts" on AIDS in any way.

    4) 5,500 random people with some scientific training is not a significant number when compared with the number of experts who espouse the retroviral theory. Additionally, I never asserted that the names on your list were fake or forged, merely that they could be, and that it was entirely irrelevent.

    5) Your classification of antiretrovirals as "extremely toxic drugs" is disingenuous and smells of trolling. This is equally true of your statement on chemotherapy, and your suggestion that the medical establishment is espousing harming patients.

    6) Your glossing over of activist groups like Act Up! or GMHC that would love to find a cover-up in AIDS research only further classifies your posts as trolling.

    I'm wasting to much time on this -- you don't want to learn enough about the subject to make an informed decision, but you doubt what is almost universally accepted among experts to be true. You say you don't trust people just because their deemed "experts", but you are going to consider alternative theories to the retroviral postulate because the people questioning it are experts?

  34. Re:A rational discussion by solferino · · Score: 2

    yes i too am wasting too much time on this discussion - yr level of discussion is disappointing me and you are now repeatedly accusing me of being a troll when yr behaviour is more amenable to such an accusation

    to wit : the three names i pulled out of this list at random according to you don't "seem to have anything to do with AIDS research. None of them has anything published in medical journals about such research. "

    after a web search i found the following information from pages at or near the top of the returned google searches

    STEVEN JONAS, M.D., M.P.H., M.S.professor of preventive medicine at the State University of New York at Stony Brook, has written eight books of his own and edited/co-authored another ten, on personal health promotion, health policy, and national politics. He has also published over 100 professional articles and book reviews, and numerous popular articles on the same subjects. He is editor of the Springer Publishing Company Series on Medical Education, an associate editor of Preventive Medicine, and a member of the editorial boards of several other professional journals in health promotion/disease prevention. A Fellow of the American College of Preventive Medicine, the New York Academy of Medicine and the American Public Health Association

    so he does not seem to be a specialist, but he does however seem to be a highly respected generalist as he sits on a number of editorial boatds and would seem to be well equipped to understand and appraise the scientific arguments

    the second person is harder to search on being of swiss background - however here are the names of two papers he has published directly on HIV/AIDS

    Albonico, H. (1991a) Lichtblicke zum zweiten Jahrzehnt in der AIDS-Forschung. Schweizerische Ærztezeitung 72: 379-380.

    Albonico, H. (1991b) Relativierung des HIV-Dogmas-Ein Beitrag zur Erweiterten Sicht von AIDS. Pädagogische Arbeitsstelle, Dortmund

    the third person is yes you are correct an expert on toxicology - he is listed on the faculty of the joint graduate program in toxicology at rutgers university as

    Sungchul Ji: Associate Professor of Pharmacy, CP; Ph. D. SUNY (Albany).

    contrary to your labelling me as a troll for describing the drugs used as highly toxic there seems to be little doubt that drugs such as AZT are heavily toxic - i cannot understand your attempting to deny this, it is readily admitted by the proponents of the drug treatment - and so the views of an expert on toxicology would seem to be highly relevant to a debate on the conventional treatment of AIDS with highly toxic drugs

    your point about there being a great deal of debate when AIDS was discovered sidesteps the conspicous lack of debate and rapid development of hegemony over the HIV hypothesis when it was first asserted several years after the early debate on AIDS

    finally you repeatedly claim that the dissidents views have been proven incorrect however the best evidence of these claims that you have offered me is a paper by a registered nurse and member of the AIDS lobby (as i responded in an earlier comment, it is almost laughable againt the large repository of papers i offered you by emminent experts and the odd nobel laureate)

    you still do not seem to understand that the size of a majority is largely irrelevant - it is very easy and usually the safest option to subscribe to groupthink - while the size and constition of a minority is extremely important, and this is why i detailed the significant number of well-credentialled dissidents to the hypothesis who are happy to publicly express their scepticism when it is clearly not in their own best personal interest to do so

    anyway we'll consider the discussion closed - i thank you for yr input, however the interchange seems only to have hardened both of our positions - i guess we will have to leave it for time to tell the eventual answer - an answer which will show the death of millions of people was caused by a mysterious virus unlike all viruses discovered before or perhaps the alternative possibility - that millions of people were poisonously treated by a medical establishment that long ago discarded the ancient hippocratic axiom of first, do no harm