Scientists Attempting to Create Simple Life Form
derubergeek writes "The Washington Post is reporting on an apparently credible project to create a simple life form in a petri dish. The goal is two-fold: 1) to actually create a unique life form essentially from scratch and (more importantly) 2) to extensively analyze and model the entire biology of this critter. Exciting and scary at the same time. From the article, it sounds as if they are quite wary of their project and fascinated at the same time. I usually refer to that sensation as 'That little voice that I should have listened to...'" There's also a NY Times article.
The project will begin with M. genitalium, a minuscule organism that lives in the genital tracts of people and may cause or contribute to some cases of urethritis, an inflammation of the urethra. The scientists will remove all genetic material from the organism, then synthesize an artificial string of genetic material, resembling a naturally occurring chromosome, that they hope will contain the minimum number of M. genitalium genes needed to sustain life. The artificial chromosome will be inserted into the hollowed-out cell, which will then be tested for its ability to survive and reproduce.
They're taking an already extant organism, "hollowing it out" as it were, and seeing if it can live and reproduce normally with a series of increasingly customized (and minimal) genetic material. Not creating something from nothing.
You are thinking of the Miller-Urey Experiment.
In the '50s they put some simple chemicals (methane, ammonia, hydrogen and water) in a sealed vessel and added energy (as electrical discharges). They found about 2% of the material formed amino acids.
"E pur si muove!" - attributed to Galileo Galilei, 1564-1642
The minimum number of genes required for an organism to survive has been a topic of interest for several years. An excellent semi-technical overview of this effort was produced by The National Academy of Sciences...
If you read the article to the end, it says why. This cell has the least number of genes of any organism known, so it is easier to reduce this to a basic minimal set than something more complex. The whole point of the experiment is to get the absolute minimum requirement of genes for basic cellular operations. So a this creature is ideally suited as it is already the most minimal set found in nature.
There are a thousand forms of subversion, but few can equal the convenience and immediacy of a cream pie -Noel Godin
The paper you talk about (Cello, Paul and Wimmer, Science 297: 1016-1018) describes the de novo synthesis of Poliovirus. The authors used polymerases in a cell-free system to translate synthetic cDNA derived from the entire polio genome. The synthetic virus did not differ significantly from the wild-type phenotype (i.e., it was not a "1000 times less potent"). Admittedly, the polymerases used were ultimately of biological origin; however there was no force vital that hindered the synthetic poliovirus. Article specifically states that vitalism was shattered, and that poliovirus is "a chemical with a life cycle". Quo vadis, neovitalism?
And the rest of your troll goes downhill from there. "Life begets life" dates back to the mid-19th century, and is an empirical observation that countered hypotheses like maggots spontaneously arising from rotting meat.
Morphogenesis is a genuine scientific concept, but there is nothing mysterious about it. These "patterns" you speak of, they sound strangely like "genes", don't they? Hmm.
I could find no reference to Penrose and a quantum description of human consciousness. This sounds bogus to me, but even if he did seriously make that claim, human consciousness is in no way a prerequisite for life. A bacterium or an earthworm has no human consciousness.
And finally emergism. Certainly, in living organisms, the whole is greater than the sum of the parts. The whole can replicate, while the parts cannot. Living organisms are emergent systems, but there is nothing mysterious about emergent systems per se.
The relation of life to matter is indeed an old philosophical problem. My own religion (Hinduism) has some very interesting perspectives on the divisions between mind, matter and spirit. However this has nothing to do with the issue at hand.
I am not personally qualified to talk about AI and whether are not it is feasible. However, judging from the rest of your post, I doubt your competence in that field of human endeavor as well.
My other sig is also a