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Drug Companies Plan Male Contraceptive Pill

TamMan2000 writes "I can hear the trolls now, with their jokes about how nobody who reads slashdot will ever score... But, incase any of us ever do score the male pill could soon be a reality."

50 of 100 comments (clear)

  1. The passing of an American tradition... by Violet+Null · · Score: 5, Funny

    ...watching the antics of celebrities and athletes as they deal with their illegitimate children in front of the media.

    Future generations will not know this joy.

  2. "Possible side effects may include... by tswinzig · · Score: 5, Funny

    ... impotence."

    --

    "And like that ... he's gone."
  3. "I'm on the pill...really." by greenhide · · Score: 5, Insightful

    I think that the technology/knowledge to create birth control pills for men has been around for a while. I imagine they will be much safer, too, since sperm is manufactured on a frequent regular basis, the pill would just have to affect that process. It could probably be taken as little as 24-36 hours before sex to have its effect, and it would most likely not affect hormone levels.

    It's just that pills for men have this one little problem:

    Zero Accountability.

    Oh, sure, if you're using them because you're in a committed relationship and don't want your honey to get pregnant, they'd be useful as heck.

    However, one of the reasons that birth control pills for women work so well is because the women taking them have a *huge* incentive to take them -- they don't want to get pregnant. So, they're much less likely to forget a dose.

    On the other hand, consider a player. He may even have pills, but forget to take them. It'll be important to him, but not as present in his mind as it would in a woman's, because the effects for him are not so dire. For the player, it might rank just above flossing as a priority.

    Also, imagine men saying, "Honey, it's cool, I'm on the pill." A woman has no real reason to lie and say that she's on the pill if she isn't, and if she does lie then she has to suffer the consequences.

    --
    Karma: Chevy Kavalierma.
    1. Re:"I'm on the pill...really." by Iainuki · · Score: 3, Informative

      Actually, you'd be surprised. Sometimes the incentives run the other way. It is not unheard for women in a failing relationship (for reasons that remain mysterious to me) to get pregnant and hope, that the pregnancy will hold the relationship together. Also, the law still requires (as far as I know) men to pay child support even if the woman lies about being on the pill and then becomes pregnant. Another reason of course is that having two contraceptive pills will presumably decrease the chances of pregnancy even further than either one alone (the female version of the pill has a small but non-zero failure rate). Similarly, the chances of pregnancy with other contraceptive measures (condoms et al.) will be decreased. A lot of its real utility depends on implementation details like cost (the female version will almost certainly be cheaper because its out of patent), dosing frequency, etc.

    2. Re:"I'm on the pill...really." by ctr2sprt · · Score: 3, Insightful
      Here's something /. readers will just get: Suspenders and a Belt. It's a good policy for computer security, and it's a good policy for safe sex. For hook-ups and other short-term relationships resulting in sex, condoms are still the way to go because of STDs; but if you've been with your partner for a long time and trust him or her, physical barrier-free sex can be a very good thing. But some girls have negative reactions to birth control pills; and some are security-minded, like the /. crowd. A male birth control pill helps out those situations.

      Plus, this is important because it gives guys a little more say in whether a girl gets pregnant. (If she gets pregnant by me, anyway.) A lot of people seem to think girls are the only ones who care about getting pregnant by accident, but... I'd have to live with myself, and that, for the rest of my life. Yes, it's not as terrible, but it's still pretty damn bad, and it's not something I'd like to see happen.

    3. Re:"I'm on the pill...really." by elemental23 · · Score: 4, Informative

      I recently spoke to my doctor about a vasectomy and he recommended continuing to use birth control for three months just to be absolutely certain there was nothing lingering in my system.

      --
      I like my women like my coffee... pale and bitter.
    4. Re:"I'm on the pill...really." by Sylver+Dragon · · Score: 3, Insightful

      Personally, I would love to have a safe and effective pill, similar to the one for women. As it is, I'm in one of those long term relationships, and we have sex frequently. My g/f is on the pill, which is nice, helps suppress acne, timing on her periods is regular, etc. Problem is, its only 98% or so effective, which means that there is a 2% chance of her getting pregent if we do it at the wrong time of the month. Cosidering that we are likely to have sex 1 to 2 times during that period, I don't really like the way the math of it starts to work out. So, we bag it. And let me tell you I hate condoms, or as we call them, the wall of anti-orgasm. They are really great if you want to go forever, you can't feel much through them. I would love to have another simple solution.
      I've often thought that a male pill would be perfect for me. She's on hers, I'm on mine, if each pill is indiviually 98% effective that's a much better risk factor, .04% I believe. I could ditch those damn condoms and just enjoy better sex. Of course, everything I have heard about the male pills, which are being tested, is that they are basically huge doses of Testosterone. Which can lead to being even harrier, more violent, and whole host of other problems. Given the choice between that and condoms, I'd choose condoms. As it is, we have just worked out a system, where by we start without it, then, as I get close, we stop and put it on. Its not perfect, and does occasionally lead to "slips" but that is what the pill is for, as a saftey net for the few times that, for whatever reason, I don't have my hat on.

      --
      Necessity is the mother of invention.
      Laziness is the father.
  4. Old news... by netringer · · Score: 3, Funny

    I heard that scientists behind "The Iron Curtain" not only developed male pill years ago - they made abetter one.

    They made a "morning after" pill for men.

    It was 100% effective.

    No patient who tried it ever got pregnant.

    --
    Ever dream you could fly? Get up from the Flight Sim. I Fly
  5. cool by austad · · Score: 5, Interesting

    This is pretty neat, but it doesn't mention how it works. They've been experimenting with the male "shot", which is basically an injection of testosterone into your leg once a week. Apparently, it's quite painful, and has many side effects, like bad acne and more body hair. One good side effect is increased muscle mass, but this is simply a good reason to have it abused by weightlifters as most steroids either stimulate the production of testosterone, or simulate testosterone itself.

    If the pill simply increases testosterone to insane levels like the shot does, it's simply a steroid and is going to have side effects similar to other steroids. When you supplement testosterone, your body stops making it's own, and that's part of the reason your nuts shrink.

    My ex-gf wanted me to get the shot when it was released because she thought taking the pill was too inconvenient. I think going in for a painful shot once a week, bad acne, and lots of hair is probably more of an inconvenience. The female pill has been around for a long time, and it's side effects (good and bad) are fairly well understood. I think the acceptance rate of a male pill will likely be slow just because it will take awhile to prove itself, and if it does just increase testosterone levels, the side effects may not be worth it.

    --
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  6. Already exists by Anonymous Coward · · Score: 5, Funny

    It's called "Geek Reality" and it's a bitter, bitter pill.

  7. FDA by xWeston · · Score: 2, Funny

    I dont think there is a real need for this anyway.

    The FDA already approved EverQuest for Birth Control Use didnt they?

    It actually works for abstinence too

    Studies showed 100% of people playing everquest had no problems with impregnating women or being impregnated.
    However, 100% of people playing everquest were also found to not leave their house, so that makes it hard.

    Everquest Approved

  8. The consequence of lying for a woman by Anonymous Coward · · Score: 4, Insightful

    Never heard of Old Dirty Bastard's 10 kids by 9 different women?

    Never heard of the Jerry Springer "I want your baby and your money" Show?

    There are many women who lie about using the pill for the express purpose of getting pregnant. Whether they do it for money (ODB) or for love (Jerry Springer style), they do it.

    A guy who sleeps around isn't looking to have a family and would more likely to be diligent in taking the medication correctly. It's a pill in the morning, not some series of injections. It's easy for a playboy to prevent exactly those things that would hamper his playing. Except for STDs of course.

  9. Never score? by gnovos · · Score: 4, Funny

    Ha, shows what you know. I'm an avid slashdot reader and I score all the time... just yesterday I got the highest Pac-Man score for the second time in three weeks!

    --
    "Your superior intellect is no match for our puny weapons!"
  10. I can see the consequence... by DocSnyder · · Score: 5, Funny
    ...that is, tons of spam:

    CHEAP VIA^H^H^HMALE PILLS ONLY $20 EACH !!!!!!

    Do you want to have GREAT SEX without your girlfriend to get PREGNANT? Check out this GREAT OPPORTUNITY! Order 10 Pills NOW and get 20 FOR FREE!

  11. which pill? by PD · · Score: 2, Funny

    I don't care what it does, but it'd better be a blue pill.

  12. Cop out by I+Am+The+Owl · · Score: 4, Funny
    Contraceptive pills are not effective. In fact, only two contraceptives are 100% effective: abstinence and reading Slashdot.

    Please, people, be responsible.

    --

    --sdem
    1. Re:Cop out by Anonymous Coward · · Score: 3, Funny

      100% effective: abstinence

      Tell that to Mary.

    2. Re:Cop out by Myco · · Score: 3, Funny
      In fact, only two contraceptives are 100% effective: abstinence and reading Slashdot.

      That's one. What's the other?

    3. Re:Cop out by I+Am+The+Owl · · Score: 2

      Of course. I apologize for including abstinence in there. It is, in fact, true that the Virgin Mary was impregnated without ever having sex.

      --

      --sdem
    4. Re:Cop out by Dr.Dubious+DDQ · · Score: 2
      That's one. What's the other?

      Laughter...

  13. It's about time! by RevAaron · · Score: 2

    It is about damn time this happened. There has been no technical or biological barriers to producing a non-painful or non-surgical male contraceptive drug like this. It is simply that pharm companies do the vast majority of contraceptive research on women and drugs to hold back their reproduction, rather than looking into the same topic on men. Eventually this comes down to our cultural meme that, for some reason, birth control is the responsibility of the woman rather than the man. A rather sexist policy held up at most drug companies.

    Hell, it may just come down to the fact that most pharm researchers are men, and that there is some curious idea men have that they're somehow less masculine if they don't have a high sperm count. Silly. I for one wouldn't mind it one bit, unless I was trying to concieve. However, most men aren't almost trying to concieve most of the time, so guys: get over it.

    All the same, I'm really glad someone took the initiative to do more than some prototype work on a contraceptive pill for men. I hope it makes it to market.

    But I can't help but wonder... does it fuck with your emotions and hormonal balance in the ways the pill, Norplant and Depo do to women? No matter how much drug companies may try to ignore this, every woman I've known that has gone on the pill or Norplant (never known a depo user) had an absolutely hellish time while her body got used to it- 2-month long periods, unnatural mood swings, huge increases in acne, weight or fatigue; no wonder the decidedly male business of drug development hasn't bothered to find a contraceptive drug for men.

    --

    Working toward a usable PDA environment in the spirit of Newton OS: Dynapad
    1. Re:It's about time! by scrytch · · Score: 2

      > There has been no technical or biological barriers to producing a non-painful or non-surgical male contraceptive drug like this

      You mean except for the side effects of steroids on the original shot, and the fact that the new pill is progestin. Oh goodie. See many women taking testosterone? Nice rant, no substance. Besides, my SO would rather wear a bulletproof vest than trust that the chamber was empty.

      --
      I've finally had it: until slashdot gets article moderation, I am not coming back.
    2. Re:It's about time! by MrResistor · · Score: 3, Insightful

      There has been no technical or biological barriers to producing a non-painful or non-surgical male contraceptive drug like this.

      Excuse me? Stopping sperm production is non-trivial. There is no natural mechanism for stopping sperm production, like there is for egg production. Doing it with drugs has generally required something like large doses of Testosterone, which has serious side effects and isn't consistent enough for practical purposes.

      Stopping egg production, on the other hand, is relatively simple, and there are various natural mechanisms in place for doing so, such as pregnancy and excessively low body fat. Low body fat is obviously a difficult thing to maintain, especially at the level where it effects fertility, and again it isn't consistent enough to be considered effective. Pregnancy, however, is very consistent, even across the animal kingdom. I don't know of a single creature that is fertile during pregnancy.

      This consistency, and the fact that it is a natural mechanism, is why there are birth control pills for women; because it's easy, not because of some aleged (imagined, IMO) prejudice that birth control is a woman's responsibility. It is a fairly simple thing to mess with a woman's biochemistry and make her body think it's pregnant, which is exactly what every birth control pill, shot, or implant does (and if you think women get side-effects from those, just wait until you have to deal with an actual pregnant woman on a daily basis!)

      does it fuck with your emotions and hormonal balance in the ways the pill, Norplant and Depo do to women?

      Of course it does, they only question is how much. There's no way it could work without messing with your hormonal balance, and there's no way your hormones are going to get messed with without having emotional and physical side-effects. The trick will be the same as it has been for female birth control; balancing effectiveness against side effects (dosage), and trading off more annoying side-effects for less annoying ones (formula).

      --
      Under capitalism man exploits man. Under communism it's the other way around.
  14. That's silly... by 8BitWimp · · Score: 2, Funny

    ....men don't get pregnant!!!!

  15. I should have included by TamMan2000 · · Score: 3, Informative

    ...this when I submitted the story, but I had not found it yet at the time...

    --
    "I'll have a Guinness, no wait, make that a Coors Light" -Grad student I work with, who shall remain anonymous...
  16. I would not use the male pill.. by molo · · Score: 2

    I don't think I would use the male pill. The reason being that it hasn't had the many many tests, trials, studies, and decades of positive experiences with low side effects that the female birth control pill has had.

    Until it becomes well tested (like 20+ years of use by the general population with KNOWN RISKS mapped out), I will steer clear of this and look for other methods.

    Just my two cents.

    --
    Using your sig line to advertise for friends is lame.
    1. Re:I would not use the male pill.. by QuantumG · · Score: 2

      Sure, but you use nutrasweet the minute it hits the shelves.

      --
      How we know is more important than what we know.
  17. May I recommend the injection? by The_Guv'na · · Score: 2

    My girl is on it, once every 3 months she has a jab in her arse. No periods/pms to worry about, which is a big bonus since she is emotionally delicate [Those of you who have been bullied 24/7 for a few years will understand], and I'm always horny ;-)

    It might not stop periods for all women though*, and I've heard some horror stories about it. I'd google some links up if I could remember the name of it. Perhaps that's why drugs have such weird names?

    Ali

    *She bleeds a little bit every 2 or 3 months, but nothing major. She forgot to tell me last time too. I don't mind a little bit like that on my dick, but when I... Nah, people might be eating.

    1. Re:May I recommend the injection? by austad · · Score: 4, Interesting

      Depo seems to work well for some people, but I've known people who have gotten pregnant while on it, like towards the end of the 3 month time frame. Also, some of the girls have experienced weight gain that they did not experience while on the pill.

      I know one person on Norplant, the implant in the arm that lasts for 6 years, and she loves it. No pills or shots, and it's been 100% effective for her so far.

      As for not getting your period on Depo, simialar effects also happen with the pill if it's 100% progesterone. Most women who take the pill take one that has both progesterone and estrogen, which is more "fault tolerant" than the straight progesterone version so if she misses a day, it's not a big deal. The progesterone version must be taken within the same hour each day, or you are supposed to use some sort of backup method. Not getting a period is not necessarily a good thing either. While it may be convenient, it's not necessarily healthy. Some women have had problems with their period not starting again when they go off Depo, which can present major problems if they want to have kids.

      Too bad vasectomies are not reversable, as that would be the safe way to go. Isn't the primary reason they are not reversable the fact that the sperm is dumped into the bloodstream and your body produces antobodies which then kill them? So if you have it reversed, your body still kills the little guys? Anyway, I'm no doctor, but I play one sometimes.

      --
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  18. Carefull! by jericho4.0 · · Score: 2

    A little piece of advice for the ladies.... If a guy says he's on the pill, use a hat anyway.

    --
    "A language that doesn't affect the way you think about programming, is not worth knowing" - Alan Perlis
  19. "Soon" == seven years by mbrubeck · · Score: 3, Informative

    Where the slashdot story says "soon", the CNN article says the product is "likely to be available in seven years."

  20. won't work by u19925 · · Score: 2

    the female contraceptive pills biggest advantage is that if females don't take it, they suffer.

  21. Male pill is actually harder. by Christopher+Thomas · · Score: 5, Insightful

    I think that the technology/knowledge to create birth control pills for men has been around for a while. I imagine they will be much safer, too, since sperm is manufactured on a frequent regular basis, the pill would just have to affect that process.

    Wrong on pretty much all counts, actually.

    Stopping ovulation in women is straightforward - you're trying to stop a once-a-month event, and the female body already has a shut-down mechanism built in (ovulation stops during pregnancy). The pill just triggers this mechanism (tricks the body into thinking it's pregnant).

    Men are designed to produce sperm all the time. There is no built-in shut-down mechanism to trigger. You also have to stop production of *all* of the hundreds of millions of sperm cells produced between sexual encounters, as opposed to stopping just one egg from being released. A male contraceptive that eliminates 99.9% of sperm production is still useless.

    And because you're trying to inhibit a function that's never normally shut down, you have to start from scratch when figuring out how to do it, and live with the fact that a male contraceptive that's 100% effective runs a real risk of causing permanent damage if not very carefully designed.

    It could probably be taken as little as 24-36 hours before sex to have its effect, and it would most likely not affect hormone levels.

    Hormone manipulation is just about the only way to affect sperm production. What do you think drives it? Hormones are the body's signalling system for stopping/starting body processes.

    It's only now, after decades of research, that relatively safe, reasonably effective approaches to male contraception are being developed, and we have a long way to go before they're mature.

    1. Re:Male pill is actually harder. by pixelated77 · · Score: 3, Informative

      A sperm count that is 99.9% lower than normal would make it extremely hard to get a woman pregnant, just ask any fertility counselor. It would be impossible to produce a contraceptive for men or women that works 100% of the time... 99.9% is conisdered good enough.

  22. Re:Depo by TamMan2000 · · Score: 3, Interesting

    I assume you are talking about depo. It is nice for all the reasons you mentioned, but there is one important thing that is not there...

    Decades of data. No studies on the long term effects of not having a period have ever been performed, the uterine lining is supposed to be flushed regularly, no body knows what leaving it in there like that does to the long term health of the uterus.

    --
    "I'll have a Guinness, no wait, make that a Coors Light" -Grad student I work with, who shall remain anonymous...
  23. I'm waiting for.... by John+Hasler · · Score: 4, Funny

    ...the male morning after pill.

    --
    Warning: this article may contain humor, sarcasm, parody, and perhaps even irony. Read at your own risk.
    1. Re:I'm waiting for.... by TripleA · · Score: 2, Funny

      That's easy as a bucket of chocolate; and called alcohol.

  24. male pill by !splut · · Score: 5, Funny

    From the official FAQ:

    Q: How was the male contraceptive pill created?
    A: As with most revolutionary discoveries, entirely by accident! A patient involved in a double blind clinical trial for an entirely different product somehow managed to cram a placebo pill into his urethra.

    Q: How does it work?
    A: The pill, or, more accurately, "penile plunger," as it has been technically termed, temporarily obstructs the outlet of the urethra. As a result, the patient is rendered infertile for a full 6 hours, after which time the pill dissolves and dislodges harmlessy.

    Q: Are there any side effects that I should know about?
    A: Being a purely mechanical devide, the male contraceptive pill has very few side effects to worry about. Acute pain and a kidney-stone-like sensation are common. Additionally, patients are advised not to drink prior to or during use of the male pill, due to a slight risk of bladder explosion.

    --
    The angel in the oatmeal.
  25. M. Jackson by SeanAhern · · Score: 3, Funny

    watching the antics of celebrities and athletes as they deal with their illegitimate children in front of the media.

    Dunno what it is, but I read that, "as they dangle their illegitimate children in front of the media.

    Michael Jackson, anyone?

  26. This isn't the pill I was thinking of by almightyjustin · · Score: 2

    I remember hearing on Loveline that a male pill was in development and much closer to market than the seven years this article cites. It would use a different method, too--instead of hormone regulation, it works by somehow paralyzing the sperm so they are ineffective. The drug itself is already used as a heart disease medication and this effect was discovered by accident at fertility clinics. This means that less testing is necessary--they only need to show that it's effective for this new function and not that it's also safe (which they already know). I can't remember the name of the thing at the moment, though.

    --

    Omnes arx vestrum sunt adiuncta nobis.

  27. Men need a valve... by km790816 · · Score: 3, Insightful

    boys should not be able to get their drivers licences until they have the valve installed. It will be closed by default. It can only be openned once the man is out of college and has a job.

    We should invest money is this! Big brother at it's best. Imagine how few losers would be around!

    (No, I'm not serious. But i think it's funny.)

  28. Re:What about the battery? by TamMan2000 · · Score: 2

    IUDs are bad! A lot of women have been killed by them, I don't want an ISD (Inter Scrotal Device)

    --
    "I'll have a Guinness, no wait, make that a Coors Light" -Grad student I work with, who shall remain anonymous...
  29. Good News by danratherfan · · Score: 2, Insightful

    The fewer humans the better.

    I've said it before, and i'll say it again...
    Abortion doctors are america's greatest heroes.

    1. Re:Good News by DAldredge · · Score: 2

      Then go stand in traffic till you get killed.

  30. In medical terms, it is... by phorm · · Score: 2

    Seven years for testing isn't extremely huge. If you find out that after 8 years of use it causes permanent sterility, impotence, etc etc.
    For myself, I'd find 15 years a short time to test something before I go swallowing a pill, or jamming a needle in my leg, no knowing the long-term side-effects.

  31. Counter-production in men, heat? by phorm · · Score: 2

    I seem to remember hearing that to actually produce at a potent level, men require a certain temperature, etc in their nether-regions. Way back when button-up tight-pants were in style (we're talking very tight, and not designed to be loose on your boys), there was a marked problem with childlessness. Seems that when the pants mashed everything together, it was too close to the body's heat and thus less production.

    I believe it's also related to why you drop down in hot climate and "tuck in" in hot weather. Perhaps something that offset the temperature balance would also act as a control method? Of course, I'm not sure if those x-century men recovered after going back to normal pants, so it may still be too permanent a solution.

  32. Yeah, and men don't? by sulli · · Score: 2
    Ever heard of child support? Or the fact that men almost always lose custody cases?

    The male pill would be enormously useful. Still it will be important to use condoms if not with a trusted partner, though, to prevent disease.

    --

    sulli
    RTFJ.
  33. Re:where's the market? by Ledge · · Score: 2

    I would. I'm not in a baby making mood at the moment, but I could be again soon.

    --
    If it ain't a Model M, it's a piece of crap.
  34. Reversible by dachshund · · Score: 2
    Too bad vasectomies are not reversable, as that would be the safe way to go. Isn't the primary reason they are not reversable the fact that the sperm is dumped into the bloodstream and your body produces antobodies which then kill them? So if you have it reversed, your body still kills the little guys? Anyway, I'm no doctor, but I play one sometimes.

    Vasectomies are entirely reversible. It can be a little tricky because the procedure is extremely delicate, and thus there isn't a 100% success rate, but it's fairly routine.

    As for all that nonsense about antibodies... Are you serious? What do you think happens to sperm when you don't have sex or masturbate for a while? Pretty much the same thing as what happens when you've had a vasectomy. I've never heard of anyone becoming sterile as a result of being celibate for a while.

    1. Re:Reversible by SmallFurryCreature · · Score: 2

      sssssshhhh you damn bastard. Geez if any girl read this you have just ruined the lines of thousands of teenage boys to get their gf's to have sex.

      --

      MMO Quests are like orgasms:

      You may solo them, I prefer them in a group.