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Will Caffeine Cause Health Problems?
numbski asks: "We're all geeks here, and I think there is no question how much we love our caffeine. What concerns me is that my fiancee has noticed how much I take in during the morning, and that I even use Diet Pepsi in addition to pain killers as a medication for headaches. So I did my googling about caffeine and addiction. In the minority, you have one report making a scientific claim that there is no such thing as an addiction to caffeine, however many other articles (not to mention marketing propaganda) suggest otherwise. Perhaps not just the sake of having an addiction is what concerns me, but whatever other side effects. I generally take good care of myself, go to the gym, exercise, play hockey, eat right. I hate to have a stroke or heart attack later on in life because of the stuff. I'd be curious to know the thoughts of others who take in large amounts of caffeine, and perhaps what their doctors have said about it. I plan on talking to my own soon, but it seems like this warrants discussion amongst those who consume the most. Would/does this prevent you from grabbing your Bawls and running like hell?"
As a matter of fact, when I don't drink it, I have these POUNDING HEADACHES LIKE A NAIL IN MY BRAIN.
Therefore, it must be good for me, right?
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Here is a snippet about sleep and addiction
The most important long-term problem is the effect that caffeine has on sleep.The half-life of caffeine in your body is about 6 hours. That means that if you consume a big cup of coffee with 200 mg of caffeine in it at 3:00 PM, by 9:00 PM about 100 mg of that caffeine is still in your system. You may be able to fall asleep, but your body probably will miss out on the benefits of deep sleep. That deficit adds up fast. The next day you feel worse, so you need caffeine as soon as you get out of bed. The cycle continues day after day. This is why 90% of Americans consume caffeine every day. Once you get in the cycle, you have to keep taking the drug. Even worse, if you try to stop taking caffeine, you get very tired and depressed and you get a terrible, splitting headache as blood vessels in the brain dilate. These negative effects force you to run back to caffeine even if you want to stop.
I don't know if this is the real answer, but they could be talking about optoisomers.
Usually the levo isomer of a drug is more active than the dextro isomer.
Example:
dextromethorphan= cough syrup, over the counter, addictive only in extremely large doses, considered non-analgesic.
levomethorphan=opiate, codeine analog, Schedule II controlled substance
Same molecule, different isomer, radically different pharmacological effects.
I've had enough abrasive sigs. Kittens are cute and fuzzy.
I am a academic clinical psychologist. I do not specialize in caffeine per se in any way, academically or clinically, but I can tell you what I know.
(1) Caffeine is not addictive in the true sense of addictive. That is, it does not lead to abnormal cravings or pathological activation of neural approach systems per se. However, it does induce withdrawal, in the sense that your body develops a tolerance to it to maintain a certain equilibrium. When you remove the caffeine, you get headaches because you're not providing the chemicals your body expects. So, it's not addictive, but it does lead to tolerance. I'm not sure if I'm explaining that well, but that's what's going on.
(2) Caffeine is known to increase levels of anxiety in various individuals. Some individuals, in fact, have acute, severe anxiety reactions to caffeine. I believe there is actually a relatively recent paper identifying the particular gene involved in this acute reaction. My guess is that you don't suffer from this, as most people who have this reaction become aware of it. But not all. And in any event, many individuals' levels of anxiety are increased by caffeine even if they don't have acute reactions. So, if you're worried about your anxiety or stress (meta-anxiety?), you might want to think about cutting caffeine and seeing if it helps. I do know various people who have stopped taking caffeinated substances and said they're much mellower and calmer people. I also know people who have starting using caffeine again after stopping it, and have commented on how much more anxious they feel. But for others, it doesn't seem to matter. You'll have to find out for yourself.
(3)As someone pointed out, caffeine habits can effect people's sleep. I once heard a rule of thumb that you shouldn't be drinking caffeinated beverages after 8:00 or so if you want to get adequate sleep. It seemed to help me; you could try it and see for yourself. Sleep problems are associated with all sorts of other issues, so even if caffeine doesn't have adverse effects directly, it may have such effects indirectly through sleep problems. But it should be okay as long as you are exposed to caffeine at appropriate times of day.
So that's what I know from that perspective. In terms of long-term physical outcomes, I don't know really. I haven't heard of such things, but I haven't paid that much attention those sorts of issues anyway.
Back in '88 I was a senior in high school. I would consume Mountain Dew x 2 in the morning to wake up. I'd have various caffinated beverages throughout the day. After work at night to stay awake for homework I'd be using Vivarin chased with as much of a 6-pack of Jolt Cola as I could stomach. Then unisom when I was done to get to sleep. Better living through chemistry I said!
It took a little while for the heart palpatations to start. I didn't like those but I was a stupid kid then. I just cut back a bit on the Jolt, but not much.
It took until early in my first year in college for the real physical effects to develop -- incredible abdominal cramps that would lay me compeltely out ina whimpering crying ball on the floor. Think appendix + gall bladder + birth. It took me a little while to start to correlate it to caffeine, but I told the doctors everything.
After ramming a wonderful camera up my tail and submitting me to a string of other humiliating tests (complete with barium enemas -- can you say "shitting rocks for 3 days?") the doctors told me that essentially I would never be able to have caffeine again without side effects because of the damage it did to my bowels & intestinal tract. I was now caffeine intolerant.
There was a drug I could take if I really didn't want the incredible abdominal cramps but it gave me nightmares. I actually tried it and the night terrors weren't worth some caffeine.
It took me 2 weeks worth of pretty nasty withdrawl symptoms before I got over it.
I have now been clean about 14 years. Nothing with caffeine, no cola, no chocolate, nothing. I read ingredients lists religiously looking for anything with more than 5gm of caffeine. A cup of Swiss Miss Hot Cocoa (5mg) gives me a pretty good buzz and I can't tolerate two of them without some mild pain.
Yes, it is a drug. Yes, it is addictive. Yes, you go through withdrawl, and yes, you can live without it. I don't know ho wmany 36 hour days I've done on sugar and micro power naps alone.
Time is the quality of nature that keeps events from happening all at once. Lately it doesn't seem to be working. -Anon
Balzac is said to have died from a heart problem induced by his love for coffee. The man was an addict. See his "The Pleasures and Pains of Coffee". Of course, one also note that the guy wrote well over a hundred novels during his career so it might have been a good trade -- depends on where your priorities are. I always thought Balzac should be the patron saint of geeks and programmers.
Soft drinks in the USA use corn syrup because it is cheaper than sugar. If you go to canada or mexico to buy sugar, it's 2-3 times chea[er than in the US.
Why is that? Because US sugar producers got congress to institute quotas on sugar imports, so cheap foreign sugar (from the carribean, etc) don't make it into the US.
For a while, some candy companies imported iced-tea mix (and other sugar-laden goodies) from foreign countries to separate the sugar out of it, because it was less expensive than to buy US sugar. Of course, that's now illegal. The Life Savers plant in Michigan closed down earlier this year, and moved to canada so they could get better sugar prices.
Who benefits? The sugar companies, and the corn syrup companies.... Most people agree that sugar-based soda tastes better than corn syrup-based soda... corn syrup would not be used if it wasn't artificially cheaper than sugar.
Unfortunately, most people don't realize the true cost of sugar quotas, and it isnt' worth writing to your congressman over an extra expense you don't realize even exists.
Do you even lift?
These aren't the 'roids you're looking for.
I say this as an M.D. who relies on a pot of coffe to get going in the morning, and 2-3 20 oz cokes and/or a vente starbucks in the afternoon:
coffee has several known effects on an organism's health:
coffee's effect on wakefulness is likely mediated by interfering with adenosine receptors in the frontal lobes of the brain (competitive antagonism). although I personally feel that coffee makes me more alert and attentive, there is always the possibility that this is a fabrication of my own self-perception. which is to say: i do not know of an objective way of supporting the statement "coffee enhances my mental functioning despite being sleep deprived."
antagonism of adenosine receptors in the heart leads to an increased tendency for the cardiac muscle to contract spontaneously. this leads to an extra contraction known as a PVC (premature ventricular contraction). i do not know what the health implications of this are. common sense would suggest that there is little consequence to this unless you have a very sick heart to begin with.
caffiene is a weak diuretic (it makes you pee). this can promote the formation of kidney stones in some people. it can also dehydrate you, which is why you should never hit the StarBucks just before you cross Death Valley by foot.
caffiene both increases acid production in the stomach and weakens the tone of the sphincter (valve) between the esophagus and the stomach. this results in gastroesophageal reflux (heart burn). gastroesophageal reflux, if severe, can lead to esophagitis, Barrett's esophagus (metaplasia, e.g. precancerous change), and adenocarcionoma (cancer) of the esophagus. i don't know of any studies that show an increased risk of developing esophageal cancer in coffee drinkers, but such a study would be retrospective and probably very difficult to pull off with sufficient power.
Lastly, and I know this is kinda weak: people who drink X number of cups of coffee each day _may_ have an increased chance of developing bladder cancer.
all in all, though, coffee is a pretty benign habit. in a public health sense, it pales in comparison to simple things, like limiting saturated fats, not smoking, moderate alcohol intake, and wearing seat belts.
Fermat's other theorem: "I have a simple proof, but I can't write it down as I fear it's a DMCA violation to discuss it"