Cloning Mammoths

Anonym Feigling writes "For your consideration... An article over at the New Zealand Herald discusses some of the challenges a japanes team faces as it attemps to develop a system to create a clone from 20,000 year-old mammoth tissue samples discovered in Siberia. It seems to me that shortly after death, any animal's/plant's "cellular repair mechanisms" (for the lack of a better...) will fail, and thus the probability of finding a single cell with perfectly intact DNA from which to create a clone is pretty well zero. Interesting stuff, but it seems that practical considerations (think code rot) would make it difficult."

Comments

Don't always need an intact DNA

[WolfWithoutAClause]

You can probably take two different, damaged copies of the DNA and PCR amplify them up, and generate a protein to stick them back together in the right way. It would be fiddly as hell, but in principle you can do it perfectly.

Once you have an intact copy of the DNA you can clone with it.

Alternatively, take the fragments of mammoth DNA and sequence them, then run the sequenced DNA through a DNA 'printer'. These machines exist- you feed in the DNA sequence on CD rom and out pops the actual DNA you want. It might take years or even decades(!) but it would certainly be possible in principle.