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Life Extending Chemical Is Found In Certain Red Wine

Squiffy writes "Yahoo is running a story from the New York Times about an interesting new find in the study of aging. It is thought that Resveratrol, a compound found in red wine, might explain why "the French live as long as anyone else despite eating fatty foods deemed threatening to the heart." Resveratrol's exact effect in humans is not yet certain, but it has been shown to extend lifespan in yeast and fruit flies, and humans "have counterpart genes that are assumed to work in a similar way." Some of the scientists involved in the study have even started with their "red wine a day". This raises the question, if a red wine a day keeps the doctor away, and you are a doctor, what happens when you start your daily regimen? Does it just keep other doctors away? Do you explode? Anyway, maybe it's time to stock up on the Pinot Noir."

37 comments

  1. Is it the wine or the grape? by samjam · · Score: 4, Informative

    I read this type of thing a lot; often though it is the grape that helps whether fermented or not, not the "wine" part.

    I suppose its what you get when you have an industry based on selling products made from processed ingredients, they present the product as being beneficial not the ingredient.

    Perhaps nothing very wrong in this, but slashdotters should at least be interested in where the real benefit lies and who benefits from the lies.

    Sam

    1. Re:Is it the wine or the grape? by samjam · · Score: 3, Informative
      To answer myself:

      From page 2 of the NY Times article at



      Dr. Sinclair said. Resveratrol, he said, is unstable on exposure to the air and "goes off within a day of popping the cork."

      ...


      Resveratrol is synthesized by plants in response to stress like lack of nutrients and fungal infection. It exists in the skin of both red and white grapes but is found in amounts 10 times as high in red wine as in white because of the different manufacturing process.

      ...


      Epidemiological studies point to red wine as containing some beneficial antidote, but it is not yet certain whether alcohol, resveratrol or a combination of the two is the active ingredient.

    2. Re:Is it the wine or the grape? by kinnell · · Score: 2, Funny
      slashdotters should at least be interested in where the real benefit lies and who benefits from the lies

      We all benefit from an excuse to drink lots of red wine on grounds that it's good for your health, so lets just keep those "lies" rolling in shall we. Thank you.

      --
      If I seem short sighted, it is because I stand on the shoulders of midgets
    3. Re:Is it the wine or the grape? by kramer2718 · · Score: 1

      According to this report. Moderate consumption of alcohol (any alcohol; not just wine) can reduce risk of coronary disease.

  2. Link to NY Times article.. by glassesmonkey · · Score: 5, Informative
    Here's the NYTimes (NO reg req) links:
    Life-Extending Chemical Is Found in Certain Red Wines &
    Study Spurs Hope of Finding Way to Increase Human Life &
    Toronto Star version

    Coincidentally, in July the FDA announced that peanuts significantly lower risk of heart disease. From the article:
    "Peanuts also contain bioactive components such as resveratrol (the substance also found in red wine), beta sitosterol, flavonoids, and antioxidants, the benefits of which nutrition scientists are only beginning to discover.
  3. Pinot's gonna cost ya... by Anonymous Coward · · Score: 2, Informative

    Anyway, maybe it's time to stock up on the Pinot Noir."

    Take some advice from an AC who's been in this hobby for a while: Pinot's gonna cost ya.

    Be a lot cheaper to drink 2 Buck Chuck.

  4. the link by TheRoss · · Score: 5, Informative

    why didn't the writeup link to the actual story?

  5. the newscientist link by Wycliffe · · Score: 1

    here is the link to the same story
    on newscientist:

    http://www.newscientist.com/news/news.jsp?id=ns9 99 94085

    1. Re:the newscientist link by Wycliffe · · Score: 2, Informative

      And here is a working link.

  6. In this case Resveratrol is in the grape by leonbrooks · · Score: 4, Informative
    See for example this University of Illinois page on the topic.

    The parent page has links to a fair few interesting snippets of information on food, most of which y'all cola-guzzling caffeine-addicted drunkards don't want to know. (-:

    Take the Google shortcut and read about:


    Germane in recent days are such gems as "preparing food suring a power failure" (linked from this health articles index).
    --
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    1. Re:In this case Resveratrol is in the grape by Anonymous Coward · · Score: 0

      Wow...you must be the life of the party.

  7. Published in Nature.. by glassesmonkey · · Score: 3, Informative
    MSNBC points to last week's publication in Nature that a chemical called resveratrol can lengthen the life of a Saccharomyces yeast cell by 80 percent
    Resveratrol activates enzymes that prevent cancer, stave off cell death and boost cellular-repair systems. A naturally occurring molecule, it builds up in under-nourished animals and plants attacked by fungi. One of the latter is the grapevine. . . But wine doesn't contain much resveratrol, and the compound degrades quickly in both the glass and the body.

    I think 20 hour work weeks, the predisposition to surrendering, and lots of romance and Jerry Lewis are more likely the culprits.
    1. Re:Published in Nature.. by glassesmonkey · · Score: 1

      Hmm, the Nature link above points to calorie restriction study of the same yeast by the same author which yields the same longevity results. This is the Nature Publication in question by Sinclair. It's the first article listed and currently the abstract is not responding.

    2. Re:Published in Nature.. by Anonymous Coward · · Score: 2, Funny

      Yeah, 80 hours work weeks, predisposition to invading oil-rich countries, and lots of ignorance and stupidity with a dab of Carrot Top won't be adding years to your life.

  8. That and a good dose of... by leonbrooks · · Score: 1

    ...light reading. (-:

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  9. French Longevity by Anonymous Coward · · Score: 2, Funny

    "the French live as long as anyone else despite eating fatty foods deemed threatening to the heart."

    Except, of course, when they're fighting Germans.

    1. Re:French Longevity by Anonymous Coward · · Score: 0
      The French fighting Germans?

      When did THAT happen?

      *rimshot*

      I kid, I kid.....

  10. UK Hospital by belroth · · Score: 4, Informative

    This doesn't come as a big surprise in Europe.
    At least one UK hospital is is giving heart attack patients wine. I try and have two glasses a day with my evening meal. It's a tough life having a healthy diet - wine, smoked salmon (any oily fish really), fresh fruit and home made bread. I don't know how I cope.

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  11. And two red wines... by Hell+O'World · · Score: 2, Funny

    keep two doctors away.

  12. Stock up? Bah! by MarkGriz · · Score: 2, Funny

    "Anyway, maybe it's time to stock up on the Pinot Noir."

    Screw that... lets start drinking (it's after 9am where I am, that's not too early is it?)

    --
    Beauty is in the eye of the beerholder.
  13. Vermouth too? by ghostlibrary · · Score: 1

    Does Vermouth (cinzano, for Hemingway fans; a fortified red wine) also have this? I can't seem to find out, and as a vermouth fan, I'd love to know my vice is healthy.

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    A.
  14. Keeping doctors away by Tom7 · · Score: 2, Interesting

    > Does it just keep other doctors away? Do you explode?

    Maybe you end up as the one who shaves the barber .

  15. Re:Too Early? by Anonymous Coward · · Score: 0

    Nah, never! It's always the right time somewhere in the world. Cheers to the evening on the other side of the globe [hic].

  16. Um, old news? by Andy+Dodd · · Score: 2, Interesting

    These studies have existed for 2-3 years or more at this point.

    A number of other studies have indicated that any form of alcohol (in moderation) can serve to reduce the risk of heart disease. Red wine may have additional benefits, but white wine and even beer have shown to be beneficial if consumed in moderation in a number of studies. (Of course, any wine will be better than beer due to the fact that wines typically have more alcohol and less carbohydrates - Beer shoots my bloodsugar up significantly, usually needing a unit of insulin per glass, while wine usually has near-neutral effects on my bloodsugar levels.)

    --
    retrorocket.o not found, launch anyway?
  17. Ahh, my first step of the twelve steps... by FFFish · · Score: 2, Funny

    ...to becoming an obnoxious French drunk!

    First step: drink red wine.
    Second step: eat stinky cheeses.
    Third step: Run! Run Away!
    Fourth step...

    (apologies to French readers. It was just too tempting a joke.)

    --

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    1. Re:Ahh, my first step of the twelve steps... by YetAnotherLogin · · Score: 1


      Cinq: Nous profitons!!

      Je ne pourrais pas resister :)

  18. Re:MOD PARENT DOWN: LINKS DON'T WORK! by Anonymous Coward · · Score: 0

    Worked just fine for me....

  19. And they call themselves editors... by afabbro · · Score: 1, Insightful

    If you've ever wanted proof that the Slashdot "editors" barely read the submissions, here it is...a submission with no link to the story.

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    1. Re:And they call themselves editors... by RobertB-DC · · Score: 1

      Hey, someone, mod parent up! I don't usually whine about the editorial staff, but I suspect that Hemos (the approving editor) decided to try out the benefits of red wine himself, as a reasearch project. Evidence:

      * As parent noted, the story has links to yahoo.com and nytimes.com... but no links to anything about the topic of the posting. You could submit a story about goatse guy with those links. Or were the editors testing whether anyone RTFA?

      * The story is long. Most good /. submissions I've seen are short and to the point. I've had a few stories accepted, and the ones that made it were the ones that packed the max info into the min space.

      * The lame, lame joke. Will a doctor who eats an apple a day explode? Heh heh, funny, but not four long sentences worth.

      Here's how I might have written this submission:

      RobertB-DC writes "Red wine may reverse the aging process, according to a *New York Times* story (*Yahoo* has a reg-impaired version). A compound called Reserveratrol, which is found in all wines, is especially concentrated in red wines. The UK scientists behind the research theorize that this is why the average Frenchman's lifespan isn't shortened by his high-fat diet. However, it is known that the relationship between the French and British is often described as 'sour grapes'."

      This version still needs some editing, but I'll save my incredible powers of submission (that doesn't sound right) for the next time I actually have a dog in the fight.

      --
      Stressed? Me? Of course not. Stress is what a rubber band feels before it breaks, silly.
  20. ummm kay by Anonymous Coward · · Score: 0
  21. Sorry for being a retard by Squiffy · · Score: 1

    Sorry I was a retard, everybody. I can't believe I forgot to link to the frickin' article! Geeze! (Kicking self -- hard) I'm just grateful no one came out and called me an idiot directly. I also agree that the article should not have been accepted. I do give myself credit for good grammar and spelling, however.

    By the way, I must confess that I *still* think the exploding doctor joke is funny. You can call me an idiot now if you want. =*)

  22. Er, yes, actually, too often I am. (-: by leonbrooks · · Score: 2, Interesting

    Bottom line: if you need to be intoxicated to have fun, you're doing it wrong.

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  23. Not news by meridoc · · Score: 2, Informative

    I did a little research into resveratrol last year. Here's some of what I found.

    The "French Paradox" was the result of a study by Serge Renaud, a French physician, published in The Lancet in 1992. He found that although French and British citizens consume approximately the same amount of calories, the British had a much larger rate of fatal heart disease. This, despite the fact that the French smoked more, exercised less, and ate more saturated fats. The largest difference in this diet study was that the French consumed red wine.

    So they decided that something in the wine gave the French an advantage. This, by the way, was televised by 60 Minutes on Nov. 17, 1991 (and an update on Nov. 5, 1995). (Yes, the TV special was on before the Renaud's article was published; studies have been going on for a while.)

    Resveratrol is synthesized in plants as an anti-fungal agent, so it's found in the skin, seeds and leaves of grapes (not the fruit or juice).

    To make wine, you squish the grapes, add yeasts, and let it ferment. The biggest difference between making red or white wine is that for red wine, you let the skins stay in the first fermentation. For whites, you filter out the skins after squishing them. Therefore, the red wine has more time to pull all the resveratrol out of the skins while it's fermenting.

    Resveratrol itself is in a class of compounds called polyphenols. A lot of polyphenols have been found in wines, and resveratrol is not the only one that is now considered beneficial (it was the first to be characterized, so it gets the glory). At any rate, most scientists think that resveratrol acts as a radical scavenger or antioxidant in the body, which is where its benefits come from. Because of this scavenging property, resveratrol can help reduce the amount of HDL ("good" cholesterol) that turns into LDL ("bad" cholesterol). That, in turn, reduces the amount of coronary heart disease.

    Don't get too many ideas about drinking a bottle a day though. A 10-year study by Gronbaek (British Medical Journal, 1995) showed that people who drank 1-2 glasses of wine a day increased longevity and decreased mortality from coronary heart disease over people who didn't drink at all. However, those who drank 4-5 glasses of wine per day still had a low mortality from CHD, but had a very high cirrhosis death rate.

    --
    "Two things are infinite: the universe and human stupidity, and I'm not sure about the former." -- Albert Einstein