Slashdot Mirror


A Gene Causing Dyslexia Found

Rovaani writes "A group of Finnish scientist have found a gene causing dyslexia. Dyslexia is the most common learning disorder among children and affects anywhere between 3 percent and 10 percent of the population."

47 comments

  1. And... by Anonymous Coward · · Score: 5, Funny

    ...in other news: Dubya stops wearing jeans.

    1. Re:And... by Alsee · · Score: 1

      If only that would solve the problem.

      -

      --
      - - You can't take something off the Internet! That's like trying to take pee out of a swimming pool.
  2. Ageing causes dyslexia? by Anonymous Coward · · Score: 1, Insightful

    But how can ageing cause dyslexia? I thought people had it when they were young?

    1. Re:Ageing causes dyslexia? by iMMersE · · Score: 5, Funny

      Have you ever seen a dead person read?

      --
      codegolf.com - smaller *is* better.
    2. Re:Ageing causes dyslexia? by Blkdeath · · Score: 1
      But how can ageing cause dyslexia? I thought people had it when they were young?

      I didn't develop dyslexia until I hit my 20s. Thankfully it's relatively mild, but transposing numbers isn't a terribly good thing in my line of work. :/

      --
      BD Phone Home!

      Shameless plug. Like you weren't expecting it.

  3. Obvious by IainHere · · Score: 3, Informative

    It has been known for over a century that dyslexia runs in families. It is common practise today to keep a particular eye on siblings of those with dyslexia in order to diagnose them quicker if they turn out also to have it.

    All this means that it is obvious that there are genes that cause dyslexia. Also, this research has been done on a single family, which will likely only find a single cause of a problem that has many causes.

    Don't get me wrong, it's great that this research is ongoing, it's just that it's of no real use, or news value.

    1. Re:Obvious by JohnPM · · Score: 2, Insightful

      I don't think you could be more wrong...unless you left out the bit about it being done in only one family.

      Firstly, just because siblings sometimes share a problem doesn't prove that it's genetic. Siblings often share a bicycle, but that doesn't mean there's a gene for that. To really prove this sort of thing you need to look at twins who preferably have grown up apart. Researches are starting to realise that even this is not always enough. Changes in gene activation can be inherited without having anything to do with the genetic code. For example, lung size in tibetans takes several generations to return to normal after moving to lower altitude. It's thought that this is something to do with methelation of the chromosomes.

      Secondly, finding a gene that causes a disease (even if there are others that remain undiscovered) does a LOT to combat the disease because you can start to target the cause. It's very little to do with proving that it's genetic rather than environmental.

      --
      Karma police, I've given all I can, it's not enough, I've given all I can, but we're still on the payroll.
    2. Re:Obvious by henrygb · · Score: 2, Insightful
      Perhaps even worse than obvious. Assuming the research has correctly idetified a particular genetic factor...

      1. In the first family, a gene called DYXC1 was disrupted. So if there is anything to this story, then the gene may help prevent dyslexia, rather than cause it.

      2. "In a complex disorder, even a modest increase in genetic risk may be interesting," they wrote. "There is overwhelming evidence that dyslexia is a genetically complex condition." So if this is really a factor, then it is likely to one factor among many, rather than an accurate diagnostic tool.

      3. To compare, the team studied 20 unrelated Finnish families, with 58 dyslexic and 61 non-dyslexic members. In the first family, a gene called DYXC1 was disrupted. In another, DYXC1 has a "stop sign" in the wrong place, which causes cells to produce a shortened version of the DYXC1 protein. So if DYXC1 is not a factor in the other 19 families, despite numberous dyslexic members, then it seems likely to be a small factor across the population.

      Quite a long way from finding the sole cause of dyslexia, which is possibly the impression tomorrow's headlines will give. Dyslexia may turn out to be something that everyone has to a degree, and only those severely affected are diagnosed.

    3. Re:Obvious by darkmeridian · · Score: 1

      I guess you might be dyslexic. The study is stating more than the fact that the illness is genetic. It is in fact suggesting a specific gene that is the putative cause of the disorder. Saying Down's Syndrome is genetic in nature is a separate thing from saying it is the result of trisomy of the 21 chromosome.

      --
      A NYC lawyer blogs. http://www.chuangblog.com/
    4. Re:Obvious by IainHere · · Score: 1

      Well, I respectfully say that I don't think your reading of the article is correct. If I understand you correctly, you're saying that they've found the single cause of dyslexia. They haven't. If you'd said "[this research has found a] specific gene that is *a* putative cause of the disorder", we'd have been much closer to agreement on this. I think the point was well made above:

      http://slashdot.org/comments.pl?sid=76258&cid=68 06 179

      Incidentally, I'm not dyslexic, but some of my best friends are :o)

  4. The human genome by Crayon+Kid · · Score: 1

    Is it just me or after the decoding of the human genome there has been an increase in DNA discoveries such as this one? (I'm not very knowledgeable in DNA issues, be gentle with me. :) )

    --
    i ate crayons when i was a kid and now i have two braincells and the blue ones taste nicer
  5. Graet by kinnell · · Score: 3, Funny

    Hofepully we cna fnid a ruce for tihs tebbirle codnition

    --
    If I seem short sighted, it is because I stand on the shoulders of midgets
    1. Re:Graet by Anonymous Coward · · Score: 2, Funny

      Headline: Dyslexia For Cure Found

    2. Re:Graet by baldass_newbie · · Score: 1

      Dyslexics of the world: Untie!

      --
      The opposite of progress is congress
    3. Re:Graet by NanoGator · · Score: 1

      "Hofepully we cna fnid a ruce for tihs tebbirle codnition "

      Pray to dog!

      --
      "Derp de derp."
    4. Re:Graet by tiled_rainbows · · Score: 1

      You hear about the devil-worshipping dyslexic?

      He sold his soul to Santa.

    5. Re:Graet by elel · · Score: 1

      If I cna raed adn wrtei wrods wiht letrtes mvoed aruodn tihs asleiy deos taht maen i ma dylsexic?

      --
      Greg Poirier -- Magic Fairy Bunny Princesses, Inc.
    6. Re:Graet by 20_ooodbye · · Score: 1

      related bad taste joke: What does DNA stand for The National Dyslexics Association

    7. Re:Graet by Anonymous Coward · · Score: 0

      lol

      I almost wish I still have mod points!!!

  6. Uh huh. by torpor · · Score: 3, Funny

    Of course, this all hinges on whether or not you believe in 'gene theory', an as yet unproven thesis which cannot be fully scientifically validated until certain international restrictions on the subject of genetic experiments are lifted ...

    Next up: the gene that makes a /. troll ...

    --
    ; -- the corruption of government starts with its secrets. a truly free people keep no secrets. --
  7. Genius Gene has been found! by erinacht · · Score: 4, Interesting

    A remarkable number of people that are rated as geniuses have/had dyslexia

    examples are:
    Leonardo DaVinci
    Michael Faraday
    Thomas Edison


    and more here.
    I wonder if they could poke the genius bit on but leave the learning difficulty out, or perhaps the different way of learning that dyslexics have makes a far better connected brain than us normal saps have

    Info about the GIFT of dyslexia

  8. And the gene responsible is . . . . . by Brahmastra · · Score: 1

    1CXYD

  9. Dyslexia "abuse" by neglige · · Score: 3, Insightful

    Dyslexia is the most common learning disorder among children and affects anywhere between 3 percent and 10 percent of the population.

    And in some cases, parents urge doctors to diagnose dyslexia so the child gets 'special' treatment (e.g. more time at exams) at school resulting in better grades...

    Yes, I know, there are children that really suffer from dyslexia, and yes, there are doctors who refuse to give a false diagnosis. But sometimes I get the feeling that the percentage of kids suffering from dyslexia is somewhat higher than 10% -- or is this a local phenomenon or my misconception?

    --
    My cats ate my karma. They also wrote this comment.
  10. The percentages seem odd by jbarr · · Score: 2, Funny

    Between 1 and 30 percent?

    --
    My mom always said, "Jim, you're 1 in a million." Given the current population, there are 7000 of me. God help us all!
  11. That Gene is a real killer. by immanis · · Score: 1, Funny

    I read that as "A Genie Causing Dyslexia Found." I just knew there couldn't be magic involved here.

    Solidarity brothers! DYSLEXICS UNTIE!

  12. People are cruel by Twylite · · Score: 3, Funny

    People are cruel. What jerk came up with the name "lisp" (the speech impediment)? And why name it "dyslexia" instead of using a suitable palindrome?

    --
    i-name =twylite [http://public.xdi.org/=twylite], see idcommons.net
    1. Re:People are cruel by Jucius+Maximus · · Score: 1
      "And why name it "dyslexia" instead of using a suitable palindrome?"

      In classic geek form, I will refute your joke with an detailed analytical post.

      I believe that the text 'lex' refers to spelling, or in general, having letters in the correct order. I have read in text comparison functions in programming languages that they do lexiographic comparisons of strings. (Can anyone confirm if it is more general than this, i.e. does it apply to more than letters?) And since dyslexia is generally associated to seeing words with letters disoriented or in the wrong order, putting dys in front of it means 'non-right-order' just like dysfunctional means non-functional.

    2. Re:People are cruel by Twylite · · Score: 1

      Ah, but you failed to account for the suffix 'ia'. Surely, given its phonetic similarity to 'ear', this would mean that dyslexia would be a functional impediment in the hearing rather than the seeing of letters in the correct order?

      --
      i-name =twylite [http://public.xdi.org/=twylite], see idcommons.net
  13. It isn't about dyslexia at all by Anonymous Coward · · Score: 0


    The researchers forgot that all their subjects were writing in Cyrillic. The gene they identified was simply the one that gives Russian women their nice thick chest hair.

  14. Irony by LadyKat · · Score: 1

    Irony is identifying a gene that garbles and confuses with a various mix of numbers and letters that are equally confusing and garbled to the rest of the world. There ya go folks, that's what a dyslexic reads! I am sure to the science community it makes perfect sense but if you are trying to address these mind boggled but brilliant people ( I am modest too :) ) the least you could do is name it Gene Bob or something easy. Dyslexics of the world UNTIE!!!

  15. Are They Sure... by Flwyd · · Score: 1

    ... it's CGTAATTCGATTA and not CAGTAGCTATTTA?

    --
    Ceci n'est pas une signature.
    1. Re:Are They Sure... by Tower · · Score: 1

      I thought it might be ACATTAG, which only seems appropriate...

      --
      "It's tough to be bilingual when you get hit in the head."
  16. Dyslexics of the World - Untie !!! by Dave21212 · · Score: 1


    First meeting to be held next week, see the website for more info.

    http://www.dyslexics.rog.uk/

    --
    "Whoever would overthrow the liberty of a nation must begin by subduing the freeness of speech."--Benjamin Franklin
    1. Re:Dyslexics of the World - Untie !!! by Anonymous Coward · · Score: 0

      http://www.dyslexics.rog.uk/



      HAHAHAHAHAHAHahahahahahahahahahahahahahaha!!!!!! !!

      Fucking weirdo!
  17. IT'S NOT FUNNY! by weeboo0104 · · Score: 1

    I have dyslexia you insensitive cold!

    --
    It is easier to build strong children than to repair broken men. -Frederick Douglass
  18. Dyslexia is a myth by Anonymous Coward · · Score: 0

    "Dyslexics" are bloody lazy. That's all there is to them. Dyslexia is NOT a disability.

    Put it this way, you see ramps in public buildings so wheelchairs can use them. This is because paraplegia is a recognised condition.

    Can you go into a library to get books with all the words jumbled about? Of course not. Therefore, Dyslexia isn't a real condition at all.

    Bloody lazy crybabies. And if there's any Bixlesics reading, here's a message just for you:

    Anif0 DPke fpadsdm plpdf FUCKOFFYOUSPASTIC ergdr

  19. Scientology by ssstraub · · Score: 1

    Didn't the Scientologists solve this already? That's what Tom Cruise says anyway...

  20. Dyslexia is not a disorder! by nanobug · · Score: 2, Informative

    It has been known for some time now that dyslexia is not a disorder, but a special ability in certain individuals that enables them to perceive objects in full 3D. That is, when they look at something, their minds instantly build a full 3D image and lets them 'see' it from all directions simultaneously, with no particular direction being any more important than the other. That is why they treat letters and words as 3D, spin them around in their mind, and often write them down backwards or in the wrong order, or confuse certain letter combinations like p and d, or N and Z.
    The researcher that first conceived of this idea found a technique that improved the reading and writing ability of 80% of dyslexsics nearly instantly: get them to imagine a camera just above their right shoulder (or left) which is looking at whatever they are looking at. Focus their attention on what the view through the camera lens would be. This slight change raises that particular viewpoint above the others in their minds.
    People with dyslexia, once they learn the above technique, have an advantage over the rest of us, and are well suited to any job involving 3D, such as architects, 3D games designers, choreographers etc.
    So we (the ones without dyslexia) have a limitation that they lack.

    1. Re:Dyslexia is not a disorder! by Red+Rocket · · Score: 1


      It's a fallacy to believe that one brain is superior to another just because it may be wired a little differently. If what you say is true, it just goes to show that dyslexics process information differently rather than showing that a non-dyslexic brain is hindered in some way. An example is the disease (or injury) that prevents people from forgetting (I think it's called hypernesia.) While it might seem like an advantage to be able to remember every single detail of your life, it's actually quite debilitating because your brain becomes so cluttered with triviality that you're unable to focus on what's important and what isn't.
      In your description of the mechanism behind dyslexia, suppose you're a hunter and you see an animal 20-meters ahead of you. A dyslexic brain would rotate the scene around until the hunter didn't know which way to throw the spear. It would seem, in this case, that the "limitation" of not arbitrarily rotating images around in our minds is actually a valuable trait.

      --
      - Hail to our fearless misleader! Fool speed ahead!
    2. Re:Dyslexia is not a disorder! by Anonymous Coward · · Score: 0

      You are so full of shit.
      really, really full of shit

  21. You're smarter than you think... by NeuroMorphus · · Score: 1

    "... randomising letters in the middle of words [has] little or no effect on the ability of skilled readers to understand the text. This is easy to denmtrasote. In a pubiltacion of New Scnieitst you could ramdinose all the letetrs, keipeng the first two and last two the same, and reibadailty would hadrly be aftcfeed. My ansaylis did not come to much beucase the thoery at the time was for shape and senqeuce retigcionon. Saberi's work sugsegts we may have some pofrweul palrlael prsooscers at work. The resaon for this is suerly that idnetiyfing coentnt by paarllel prseocsing speeds up regnicoiton. We only need the first and last two letetrs to spot chganes in meniang"

    --

    python >>>
    reduce(lambda x,y:x+y,map(lambda x:chr(ord(x)^42),tuple('zS^BED\nX_FOY\x0b')))
  22. Hmm, maybe I've got it by josath · · Score: 1

    Hehe, I just read the title as "A Game Causing Dyslexia Found"

    --
    sig? uhh, umm, ok
  23. Some more light on dyslexia by nimblebrain · · Score: 1

    From some of my readings (New Scientist, IIRC), humans have an area for reading that is specialized on the left hand side that makes it more amenable for reading. The mirror brain area on the right hand side has kept its function from primates. In primates, both sides have the same function.

    So what is the function of this magical area?

    Experiments have determined that it seems to be used to recognize various kinds of shapes without regard to its three-dimensional orientation. There are a limited number of shapes it can discern, which might indicate that the shapes involved in human reading and writing are bound by certain limitations.

    I don't imagine the trouble is in the area itself, given its function, and the fact that young children frequently have 'dyslexic' effects as they learn to read and write (hence the archetypal backwards S and N of children's crayon masterpieces). Spoons and cats don't vary in function by orientation, but b, d, p and q certainly do... so I imagine there's something in post-processing (likely also on the left side) that can learn and handle orientation-specific symbols.

    I saw an interesting videotape showing 'normal' folks what it would be like to live with dyslexia. They took all the d's, p's, b's and q's, mixed them up, shuffled the vertical spacing inside words and changes where the spaces were. You could make out what the text was with a little effort, but it drove home the point that if you have to take the time to "decode" something instead of being able to merely "read" it, it's much harder to remember the content.

    One interesting comment a dyslexic coworker mentioned to me was that wearing glasses that slowed down reading actually helped. I don't know the theory behind why it works, but good results bear investigation.

    --
    Binary geeks can count to 1,023 on their fingers :)
  24. finally by combinatorics · · Score: 0

    ...gnitanicaf

    --
    Dada ended art.