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Nietzsche's Toxicology

CETS writes "If it doesn't kill ya' it makes you stronger, so a little bit of a bad thing might be alright, according to Scientific American which has this article. " If dioxin and ionizing radiation cause cancer, then it stands to reason that less exposure to them should improve public health. If mercury, lead and PCBs impair intellectual development, then less should be more. But a growing body of data suggests that environmental contaminants may not always be poisonous--they may actually be good for you at low levels.""

29 of 109 comments (clear)

  1. BUSH! by ArmorFiend · · Score: 4, Funny

    This report on toxic chemicals brought to you by the Presidential Council on Industrial Development.

    1. Re:BUSH! by Monkelectric · · Score: 3, Insightful
      No SHIT! That was my first thought. We're gonna fix Iraq/Afghanistan by blowing it up, we're gonna save the forest by turning into paper, we're gonna save the economy by giving money to people who've already got alot of it, and now the best lie ever, toxic chemicals are good for you.

      Tell me something, how the fuck did humans live without toxic chemicals for the last 100,000 years then?

      --

      Religion is a gateway psychosis. -- Dave Foley

  2. Poison by hackwrench · · Score: 4, Interesting

    Practically everything is poisonous in sufficient amounts.

    1. Re:Poison by Tyrdium · · Score: 2, Funny

      Too much water will kill you.
      Duh!

    2. Re:Poison by SeaEye420 · · Score: 3, Insightful

      I saw this on Penn & Teller's Bullshit. It was hilarious. Great show, btw. They were going around at a greenpeace rally and getting everyone to sign a petition to ban Dihydrogen monoxide(sp?) due to the dangers. All kinds of 'activists' bought it hook, line, and sinker.

      It really showed that many people who consider themselves to be activists are nothing more than cheerleaders for a cause without doing any critical thinking or research about whose and what ideals they are supporting.

      Know anyone like that? :-D

      --
      Wort Wort Wort!
    3. Re:Poison by R.Caley · · Score: 2, Insightful
      people with no chemistry background would likely not figure it out at all

      People with no chemistry background should be very rare in any developed country. If this is not the case where you live, congratulations, your school system is terminally screwed.

      It is very likely that the interviewed 'activists' [...] unthinkingly said 'yes' to an interviewer asking if they wanted to sign a petition against a 'Very Dangerous Chemical'?

      The key word here is `unthinkingly'. By using it you are agreeing that the people who agreed deserved to be laughed at.

      --
      _O_
      .|<
      The named which can be named is not the true named
  3. nothing new. by joFFeman · · Score: 4, Informative

    george carlin's been saying this for years.

    --
    "Life is great; without it, you'd be dead." -Harmony Korine
  4. Bush or Bush League by Anonymous Coward · · Score: 2, Funny

    Bush League, definitely.

    Another B.L. finding: It is healthier for you to be poor. However, families that have been very rich for a long time develop an antidote, so it is okay for BLers to be rich.

  5. Now I understand.. by Sylver+Dragon · · Score: 2, Interesting

    Why all those old rich people keep moving to places like Palm Springs:

    Prolonged exposure to extreme temperatures is also harmful, but Rattan has found that heating up human skin cells to 41 degrees Celsius (106 degrees Fahrenheit) twice a week for an hour slows aging in the cells.

    Seriously, if you've never been though Palm Springs, CA, you aren't missing much. Its a couple of golf courses in the hottest damn place, its not quite the middle of nowhere, but its in the same zipcode. Though, I might just be bitter about it, because the first job I ever held involved delivering medicines to people, in home, and I had to drive to Palm Springs every other week in a truck with no A/C. Nice enough drive, little to no traffic, and the desert can be kinda pretty at the right times, but if its summer take a lot of water with you.

    --
    Necessity is the mother of invention.
    Laziness is the father.
  6. How many cigarettes a day is optimal? by exp(pi*sqrt(163)) · · Score: 4, Funny

    I ask.

    --
    Doesn't it make you feel good to know that our freedoms are protected by politicans, lawyers and journalists.
    1. Re:How many cigarettes a day is optimal? by benjamindees · · Score: 2, Funny

      What was that sci-fi movie in which hot chicks from the future have to smoke when they come to our time because the air in the future is so polluted? I think it involved kidnapping people from airplanes...

      --
      "I assumed blithely that there were no elves out there in the darkness"
    2. Re:How many cigarettes a day is optimal? by pmz · · Score: 2, Funny

      How many cigarettes a day is optimal?

      Well, smoke can keep insects away. And, insects can carry diseases like malaria and west nile. What are the odds of a smoker in a swampy area quitting smoking and, then, dying of west nile one month later?

      Fact is, some smoking doesn't kill anyone. Chain smoking artificially-enhanced cigarettes for forty years does.

  7. Pollution is killing me! by Dr.+Bent · · Score: 4, Funny

    I've done tests myself that prove my tap water contains Dihydrogen Monoxide, but the government won't do anything about it. They say it's naturally occuring. Never mind that it kills 350 children under the age of six every year, and countless others who frequent beaches and lakes where industrial plants dump the stuff.

    I'm no scientist, but it's obvious to me that we need stricter envrionmental controls to regulate this kind of thing. Multinationals are going to destroy the planet unless we do something.

    1. Re:Pollution is killing me! by Flingles · · Score: 2, Funny

      Despite the known dangers of DHMO, it continues to be used daily by industry, government, and even in private homes across the U.S. and worldwide. Some of the well-known uses of Dihydrogen Monoxide are: .....by elite athletes to improve performance
      Please explain!?

      --
      Karma: -2^0.5 . Mainly due to the imbibing of dihydrogen monoxide
  8. No it doesn't... by Jerf · · Score: 4, Informative

    ...because homeopathy explicitly includes the idea that things get more powerful as the dilution decreases, even past the point that the original substance no longer has even a molecule in the final product. A homeopathy practictioner would thus claim that these exposures are at far too high a level to work, and still need to be diluted by a factor of, oh, at least 10^10 to be more useful, probably more. (That number is not a typo. Yes, Homeopathy shoots right past Advogadro's Number and never looks back.) Homeopathy explicitly claims to be many times more beneficial then these low-level exposures. As they are completely wrong, they still don't win any points. (Nor is this as big a surprise as the article writer thinks it is, it merely establishes some examples of a long-known general principle.)

    For those wishing to learn more about homeopathy, please see Homeowatch, and in particular this page which provides an overview of homeopathy.

    1. Re:No it doesn't... by Anonymous Coward · · Score: 3, Funny

      [...]oh, at least 10^10 to be more useful, probably more. (That number is not a typo. Yes, Homeopathy shoots right past Advogadro's Number and never looks back.)

      Avogadro's Number: ~6.02 x 10^23

      FYI, 10^23 > 10^10

  9. Ban DHMO! by n1ywb · · Score: 3, Funny

    Ban DHMO! Dihydrogen Monoxide (DHMO) is a colorless and odorless chemical compound. Each year, Dihydrogen Monoxide is a known causative component in many thousands of deaths and is a major contributor to millions upon millions of dollars in damage to property and the environment.

    --
    -73, de n1ywb
    www.n1ywb.com
  10. Hormesis by crmartin · · Score: 3, Interesting

    This isn't really news -- except to the majority of people who listen to the ecological ideologues rather than checking out the actual data. It's been known for thirty or forty years that places with high background radiation (like Colorado, especially Pueblo and Grand Junction) have suspiciously low cancer rates, and that these cancer rates absolutely contradicted the EPA's most common assumption, of a completely linear dose-response rate. (That is, what is called the "conservative assumption" is that the response to low doses of radiation is linear because at doses above about 30 roentgen the response is linear.)

    One interesting thing about this is that, if hormesis is true, as it appeaers, then all those people who have spent a small fortune clearing radon out of their basemants may have actually increased their chances of cancer.

    Here's another link, this from Discover magazine.

    1. Re:Hormesis by penguin7of9 · · Score: 3, Insightful

      It's been known for thirty or forty years that places with high background radiation (like Colorado, especially Pueblo and Grand Junction) have suspiciously low cancer rates, and that these cancer rates absolutely contradicted the EPA's most common assumption, of a completely linear dose-response rate.

      There are many possible reasons for this; maybe Colorado just has a better public health system or healthier lifestyles.

      One interesting thing about this is that, if hormesis is true, as it appeaers, then all those people who have spent a small fortune clearing radon out of their basemants may have actually increased their chances of cancer.

      Even if Radon did protect you against cancer in low doses, the right thing to do would be to get it out of homes and then give it to people it in well-controlled doses.

      It is quite ironic that people like you often call themselves "conservatives", but then want to subject the US population to historically unprecedented exposures to largely unstudied chemicals and radiation. The conservative thing is to avoid exposing people to new chemicals and radioactivity until we know for certain that it's safe.

      This isn't really news -- except to the majority of people who listen to the ecological ideologues rather than checking out the actual data.

      You are right: this isn't news. The only news is that ignorant politicians with a corporatist agenda use such obscure scientific tidbits out of context to argue that pollution is harmless.

  11. I have researched this phenomenon by VendingMenace · · Score: 5, Informative

    At Lawrence Livermore National Laboratory. It is know as adaptive response. The acticle is slightly misleading though. What is actually observed is that organisms which are exposed to small quantities of a toxin (lets say radiation) before being given a larger dose will experience less damage than those who were exposed to the larger dose without the small "priming" dose.

    For example, cells in group A are exposed to a small dose, of raidation, given a few hours to sit around and then are exposed to a large dose of radiation. Group B is exposed to the large dose or radiatoin only. It can then be observed that group A suffers less damage (we quantified it by looking at the damage to the chromosomes, translocations, ect.) than those in group B.

    Some caveates to this are...
    -If the large dose of radiation is too large, you will not see this adaptive response.
    -The time that the cells must wait after teh priming dose is about 6 hours, to short or too long a time and the adaptive response is not observed
    -The priming dose also must be within a range of certain values for adaptive response to take place
    -In some cases, you see a synergisti response in the radiation. That is the cells exposed to the priming and large dose experience MORE radiation than is expected from just the sum of the radiation that they were exposed too

    All the research we did pointed to the fact that there is probably some kind of repair mechanism that is turned on when chromosomes are damaged. By exposing cells to a small priming dose of radiation, you have turned on this mechanism. Thus, when you expose the cells to the larger dose of radiation this repair mechanism is already turned on and the cell can more readily deal with the damage than other cells that have not recived this priming dose.

    THis is pretty cool research when you think about it. I mean it affeects alot of stuff, esp in the medical feild. Think about chemotherapy. The idea is to kill cancer by exposing it to a dose or posion. However, the dose that is given is just caculated by body mass. This research alludes to the fact, however, that not all peope will respond the same to long term exposure to posoins. THe long term exposer acts almost like many many priming doses, and, in those people that exhibit greater adaptive response, the therapy will then be less effective. INtersting, no?

    Also, there have been several different studies concerning geographical location in the US vs cancer frequecies (melenoma, to be exact). It was found that peope who lived in higher elevations (and thus recieved contiually doses of radiation that were higher than those at low elevations) had less occurance of skin cancer, than those of us at lower elevations. It is definatly hard to prove any connection, but hte thought was that this higher dose of radiation acted like a priming dose and then the higher doses of radiation that people are exposed to durring the summer had less of an effect.

    Anyways, i just wanted to vouch for the article and say that the stuff the are talking about (however, misrepresented) does exist. THe practicalitly of it, and how much you should let it affect your behavior (still wear sunscreen!) is up to you. IT is not a very well understood phenomenon, but it is still cool.

    SWEET!

    1. Re:I have researched this phenomenon by Sgt+York · · Score: 2, Informative
      The same thing happens in many models, the one I am most familiar with is hypoxia. Exposing cultures, in situ tissues or even whole animals to short periods of "light" hypoxia will protect them from more severe hypoxia for a period of time. (Look on Pubmed for Kitakaze and his research on nucleotidase in the heart). However, the effect is short term. It only lasts for a few hours.

      THe long term exposer acts almost like many many priming doses, and, in those people that exhibit greater adaptive response, the therapy will then be less effective. and the caveat, If the large dose of radiation is too large, you will not see this adaptive response

      Although I don't know what the limits are in your work, I imagine (perhaps incorrectly) that the doses given in most radiation treatments are a bit large for adaptive response to kick in before the damage is too great. Besides, the (observed!) drecrease in efficacy of radiation treatment over time is probably quite well explained by natural selection. The first few doses kill off the cancerous cells that are sensitive to radiation, leaving only those that are less sensitive.

      It's not always good, either. If you prime your liver with ethanol, and get the cleanup pathways activated, then take in a sublethal (for normal circumstances) dose of methanol, it will kill you. Because the pathways are already going full blast, the methanol is converted into its toxic breakdown products much more rapidly. Ying and Yang.

      One last thing, because most of these responses are due to the activiation of a repair pathway, the protection given is short lived. These pathways are timed, and shut down after the stimulus is gone, at least normally. This is a Good Thing. Repair pathways gone awry are not good (some tumors, fibrosis, "Proud Flesh").

      --

      There is a reason for everything. Sometimes that reason just sucks.

  12. Return of Mithridatism by monopole · · Score: 5, Interesting

    Mithridatism, the practice of ingesting small quantities of poison to develop a resistance has been practiced since ancient times. The name comes from Mithridates, king of ancient Pontus, who fearful of being poisoned, ingested small quanties at regular intervals develop a resistance. Dashiell Hammett descibes the use of Mithridatism to develop a resistance to arsenic in the Continental Op story "Fly Paper" (1929) which in turn references the practice as per Dumas in "The Count of Monte Cristo". Thus it is relatively well known that trace doses of some poisons can result in relative imunity to the specific toxin. This does not imply that the paractice is particularly healthy or desirable.

  13. Iocaine Powder by eviltypeguy · · Score: 3, Funny

    This article has been spouting the truth I've known for a while.

    I've been building up my resistance to the effects of Iocaine Powder. Never know when you're death is going to be on the line with a Sicilian opponnent.

    1. Re:Iocaine Powder by Anonymous Coward · · Score: 2, Funny

      You keep saying that word. I do not think it means what you think it means. :-)

  14. Why isn't this obvious? by MarkusQ · · Score: 3, Insightful

    Every time this comes up I am amazed that it isn't completely obvious to almost everyone. After all, every substance known to man has the Goldilocks Property (too much is bad, too little is bad, so just right is best). It seems like everyone wants to pretend that they live in a world where things are either good or bad in-and-of themselves, when in fact nothing they have ever encountered works the way they are trying to pretend that everything does.

    The only explanation I can think of is that it would be great for people who don't want to think, except that in a would like that people never would have evolved in the first place.

    -- MarkusQ

  15. Yet another lesson from nethack by dasunt · · Score: 2, Funny

    Yet another one of life's lessons that can be learned from nethack.

    If the poison does not kill you, it will probably drop your strength, thus making you weaker.

  16. Cumulative Toxins by quinkin · · Score: 4, Funny
    In cases where the toxin is actually cumulative (ie. is stored by the body), such as many heavy metals, it is not recommended.

    Please don't have your daily lead/mercury tonic...

    Q.

    --
    Insert Signature Here
  17. Re:Whatever ... by crmartin · · Score: 4, Interesting

    It's sorta off topic, but what Freddie baby actually said is "Was mich nicht umbringt, macht mich noch staerker". The important verb "umbringen" means "to kill, to murder, to liquidate" and it's got sort of the sense of "bringing down" that we'd have if we spoke of bringing down a deer with hounds.

    So it's really something like "That which can't catch me and kill me makes me even faster and stronger."

  18. This is true within reason by chia_monkey · · Score: 2, Insightful

    I agree with this (hell, how can't I? It's been proven) to some degree. It always drives me nuts when I see parents sheilding their kids from every sort of germ and such and fill them full of motrin at the slightest hint of a cold. Let them get sick. Let them build up their immunities. Let the body build resistance to it. It's only gonna happen by playing in the dirt, being outside, experiencing the world. Stop disinfecting the entire house. And as we've seen throughout history (and by some posts here), it's been a common practice to ingest small amounts of poison to build up the tolerance so if you were to ingest a "lethal" dosage for a "normal" person, you'd survive.

    However...you are NOT going to catch me smoking cigarettes to "build up" my lungs, or drink gasoline, or take in any other number of highly toxic (and those weren't even "highly toxic") compounds to "get stronger". Yet...scarily enough, some people in society don't bother to use common sense and they'll just be a bunch of lemmings and do stupid shit and start drinking anti-freeze thinking it'll help them in some way.

    --

    "He uses statistics as a drunken man uses lampposts...for support rather than illumination." - Andrew Lang