Smallpox Vaccine Could Prevent AIDS

An anonymous reader writes "Researchers at George Mason University have published a preliminary report which suggests that the Smallpox vaccine might be able to slow the spread of AIDS. Various news stories have suggested that it may be due to the vaccine interacting with the CCR5 receptor, which is a cellular infection route in another related poxvirus, and also commented on the rise of AIDS in the years after smallpox was declared eradicated and the smallpox vaccine was no longer given as a matter of course."

Comments

All military vaccinated. No serious side-effects.

[Futurepower(R)]

Addition to my parent post: This article on a U.S. military web site implies that ALL U.S. military personnel are vaccinated against smallpox: Smallpox Research Project Data Presented

Apparently they were doing what I suggested in my parent post, although the research report doesn't say that: GMU, GW in Patent, Ethics Dispute. The Washington Post article is badly reported, because it doesn't mention the scientific basis for believing smallpox vaccine could stop AIDS.

Re:All military vaccinated. No serious side-effect

[thinmac]

Well, not *all* U.S. military personnel get the smallpox vaccine. How do I know? I'm one of the ones who hasn't recieved it yet.

The official line is that people get the vaccine if they are deployed in an area in which smallpox is "endemic". I put quotes around it because obviously it's not endemic to anywhere anymore, but the general wisdom is that that means anywhere they're likely to drop it on us.

So, if you're in Iraq you get it, obviously. If you're in San Diego and are unlikely to get deployed elsewhere any time soon, you don't. I'm not sure about places like Germany or Japan, where there are large U.S. installations but not a huge risk of biological attack.

A lot of people are getting it, though. The study you suggest would almost certainly be worthwhile.

HIV-Smallpox Interplay =~ Asthma-Measles Interplay

[reporter]

The fascinating quote is below.

Based on the natural history or spread of HIV in Africa, Weinstein and Alibek proposed that declining immunological responses to smallpox -- due to the elimination of the disease and the discontinuation of immunizations -- may have been associated with the emergence of HIV.

This observation bears an uncanny resemblance to the observation that eliminating various childhood diseases causes a person to later become susceptible to other illnesses. Please visit the web site, "MEDIA REPORTS ASK THE QUESTION: IS THE CURE WORSE THAN THE DISEASE? ". In "Plagued by Cures", "The Economist" observes that the incidence of asthma rose sharply after the elimination of measles, for example.

I would wager good money that Dr. Raymond Weinstein has stumbled onto the cure for AIDS. Please read "Smallpox Vaccine Could Prevent AIDS". All previous attempts tried to attack HIV directly but failed because the virus (1) mutates too rapidly for vaccinations to succeed or (2) cleverly hides in remote cells that anti-viral drugs cannot reach. On the other hand, this proposal by Weinstein to use smallpox vaccination to close the door (i. e. the CCR5 receptor) to HIV infection instead of killing the virus directly just might stop HIV infection.

I am optimistic.

... from the desk of the reporter

Re:HIV+AIDS=Biggest Hoax of 20th century

[inertia187]

I don't know what to think about this. But there are apparently a lot of "authorities" who say this.

If it's a hoax, they've pulled the wool pretty well. Not only the population, but every medical journal too.