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Worm Lifespan Extended To Five to Six Times Normal

Trillian_1138 writes "Scientific America has a brief article, only two paragraphs, sumarizing research from a recently released longevity study done on worms. The worms, Caenorhabditis elegans, have been known to live 124 days, "the equivalent of a human reaching his 500th birthday." In addition, in worms which had their insulin-like growth factor 1 (IGF-1) altere, "lived six times longer than normal worms and remained active for most of their lives." "These life-span extensions, which are the longest mean life-span extensions every produced in any organism, are particularly intriguing," the team writes, "because the insulin/IGF-1 pathway controls longevity in many species, including mammals." Humans already live significantly longer than only a century ago, in large part simply from hygiene advances. What might the effects on society be if gene therapy or other medical treatement humans lived to be 500?"

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  1. But can the brain handle it? by G4from128k · · Score: 4, Insightful

    I've no doubt that we can cleverly shift the pace of the aging clock, but can we tweak the biochemical algorithms of the brain to handle life and learning over a 500 year span. If a person takes this drug when they are young, do they need to learn (or can they learn as easily as children learn) until they are 50 or 100? Will having too many 400 year-olds in the population hold back progess because they will veiw all the inventions of the last 380 years with suspicion? What about having 500 years of accumulated heartbreaks, lost friends, daily frustrations, etc?

    Its one thing to physically live for 500 years, its another thing to mentally thrive for that long. Even if our bodies can be tweaked to last, its not clear that our minds can.

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