Vertical Ergonomic Devices for Linux?

NonNullSet asks: "I am having trouble finding a truly programmable mouse for Linux. I'm a longtime (read older) computer user and have to use an ergonomic mouse (http://www.evoluent.biz) to work on Windows. I would like to find something similar (vertical shape, if possible, programmable buttons) for Linux, but haven't had any luck. Have any Slashdot readers been successful at finding/using programmable ergonomic hardware on Linux? Vertical shape plus click and hold would be excellent!"