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Nanotechnology: the Good, the Bad, the Hyperbole

pillageplunder writes "A very informative interview with Kristen Kulinowski who is an executive Director at the Federally funded Center for Biological and Environmental Nanotechnology at Rice University. A good well balanced read."

39 of 141 comments (clear)

  1. Hmmm by Anonymous Coward · · Score: 5, Funny

    I don't have the smallest interest in nanotech.

    1. Re:Hmmm by grungebox · · Score: 4, Funny
      I feel like an ass. I wrote a lengthy post about how nanoscience, although possibly opening up a Pandora's Box, could be used to benefit society.

      Then, of course, I got your joke. Man...I have this inner troll that just wants to flamebait out.

  2. Re:Worst description ever! by prat393 · · Score: 2, Funny

    Actually, go ahead and slashdot the www.ruf.rice.edu - that way, I'll have an excuse for some of the work that I was supposed to turn in yesterday (I'm a student at Rice).

  3. Article by Anonymous Coward · · Score: 2, Informative

    Nanotech: Beyond the Hype -- and Fear
    Kristen Kulinowski's job at the Center for Biological & Environmental Nanotechnology is "to draw attention to proactive, responsible development"

    In recent years, an eclectic band of scientists has mapped out a new frontier known broadly as nanotechnology. Though they're from different traditions and methods, these explorers, who include biologists, chemists, physicists, chipmakers, and computational experts, have tackled the same basic question: how to control the building blocks of matter from the bottom up.
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    They're learning how to guide individual atoms as they combine to form molecules and, in turn, how to make materials -- molecule-by-molecule -- that don't exist in nature. Their work cuts across some of the hottest areas of science, including innovative drug-delivery systems, cancer treatments, ultrastrong lightweight metals, and mass-produced superconducting wires -- to name a few.

    Nanotechnology is surrounded by hyperbole, for good reason. It arguably shows as much promise in both science and business as any other major technology of the past century, including nuclear energy in the 1950s or genetics in the 1990s. Yet before business rushes headlong into a nano-tomorrow, an assessment of the risks nanotechnology poses to public health and the environment needs to be done. Just as nuclear waste and the flap over genetically modified foods tainted the promise of what were supposed to be transforming technologies, many people are concerned that nanomaterials could create problems if introduced without thorough testing.

    LESSONS LEARNED. Kristen Kulinowski is uniquely positioned to help separate nanotech hype from reality. As a chemistry faculty member and executive director for Education & Public Policy of the federally funded Center for Biological & Environmental Nanotechnology (CBEN) at Rice University, she believes that scientists are applying the lessons learned from past disappointments. Well in advance of major commercial production, testing of nanomaterials on living organisms is under way in university labs. And already, federal agencies such as the Food & Drug Administration and the Environmental Protection Agency are exploring regulation that will help ensure that commercialized nanotech is more a dream than a nightmare.

    Kulinowski does have concerns that in the near term -- before the basic science is even ironed out -- nanotech research could be derailed by outside factors. Already, nascent signs of dot-com style hucksterism are appearing, with companies making nanotech claims of dubious scientific merit. Conversely, Kulinowski adds, others are fearful of the perils of nanomaterials without understanding the underlying science.

    BusinessWeek Industries Editor Adam Aston recently met Kulinowski in Houston, where she talked about some of nanotech's most promising areas and her commitment to help inform public understanding and policy this new area. Here are edited excerpts of their conversation:

    Q: What worries you about the public's response to nanotechnology?
    A: I'm worried about an overreaction to both the hype and the fear. Every time a research article comes out talking about a certain type of risk, a dozen high-profile media stories ring alarm bells but fail to explain all the nuances of the study -- that results need to be repeated, or that concentrations of nanomaterials used in lab studies are unlikely to occur in nature. This sort of alarmist coverage can affect lawmakers as well as the public.

    So one of my jobs is to help inform science policymakers in Washington. Likewise, the reactions to positive stories can be overdone -- driving unrealistic expectations about miracle cures or how soon new nanomaterials may be available.

    Q: What are the real risks?
    A: There are two broad categories of risk assessment going on right now. One is in biological systems -- starting with the effects on individual cells and up to more sophisticated organisms such

  4. DNA Robot Walks by mgoulding · · Score: 5, Interesting

    Speaking of nanotechnology - some chemists at NYU have made a walking DNA robot. Read about it here.

    1. Re:DNA Robot Walks by fugspit · · Score: 4, Informative
      Or for a summarised version, You can the the always enjoyable Register version

      Shocking stuff, A robot with strands of DNA for legs!

      While you're there you can also read about nano trees. The creators speculate that the technology could lead to "three-dimensionally interconnected computing structures analogous to the brain".

  5. Grey goo by bcmm · · Score: 5, Informative

    We've had a lot of rubbish about nanotech here in the UK, including the belief that a flesh-eating grey goo will take over the world. Honestly, our tabloid papers will report anything...

    --
    # cat /dev/mem | strings | grep -i llama
    Damn, my RAM is full of llamas.
  6. Re:Worst description ever! by Anonymous Coward · · Score: 4, Funny

    Uninformative yet balanced :)

  7. Re:Michael Crichton by grahams · · Score: 4, Funny

    Psst. It's fiction.

  8. Wishlist by Anonymous Coward · · Score: 5, Interesting

    Reply with your wishlist of what you want nanotech to do in the future.

    Here's mine:
    - "Atomically" precise manufacturing, for the cost of energy and material.
    - Greatly improved materials research.
    - Ultra cheap and efficient solar cells.
    - Recycle nearly anything for raw materials.

    1. Re:Wishlist by nelsonal · · Score: 2, Insightful

      That sounds great, until the bots kill all the E. Coli in my gut causeing me to die of indigestion.

      --
      Degaussing scares the bad magnetism out of the monitor and fills it with good karma.
  9. Nanotech is already here... by StevenMaurer · · Score: 5, Insightful

    You have it in your PCs and disk drives. This form of nanotech has a bright future.

    What isn't here, and probably never will be, is the SciFi "self-assembly" nanotech. Throw out some powder on a rock and watch it turn it into a new car. Or something equally silly.

    Strangely, we don't expect steam shovels to make other steam shovels. We don't expect cars to run without gasoline. And we certainly don't expect it to all just work without breaking down. But make the robotics very very small, and suddenly magic is supposed to occur.

    1. Re:Nanotech is already here... by Anonymous Coward · · Score: 2, Insightful

      We don't expect beach balls to be on both sides of the net at the same time, either. Make robotics very small, and it's not magic, but quantum effects and scale-invariance, that occurs.

    2. Re:Nanotech is already here... by Mr.+Slippery · · Score: 5, Insightful
      Strangely, we don't expect steam shovels to make other steam shovels. We don't expect cars to run without gasoline. And we certainly don't expect it to all just work without breaking down. But make the robotics very very small, and suddenly magic is supposed to occur.

      There already exist entitites that make others of their type, operate on chemical energy from the enviroment, and are self-repairing. We call them "bacteria".

      It is not unreasonable to expect that at some point in the future we will be able to create machines with these characteristics.

      --
      Tom Swiss | the infamous tms | my blog
      You cannot wash away blood with blood
    3. Re:Nanotech is already here... by dano1992 · · Score: 3, Funny

      "What isn't here, and probably never will be, is the SciFi "self-assembly" nanotech. Throw out some powder on a rock and watch it turn it into a new car. Or something equally silly."

      Well I'm a sucker, then. The guy at the garden store talked me into buying this packet of seeds. Said if I just sprinkled them on some dirt, in 3 months I'd have tomatoes. Too bad I didn't see your post first. Then I'd know he had no idea what he was talking about.

    4. Re:Nanotech is already here... by Eagle5596 · · Score: 5, Funny

      It is not unreasonable to expect that at some point in the future we will be able to create machines with these characteristics.

      Not unreasonable? Next thing you know you'll be telling me that we'll be able to make flying machines! How absurd! Even if we could make such "flying machines" as you suggest, I see no use for them what so ever. Whats next? Suggesting we could send voice over wires? ABSURD I TELL YOU! What use would such a device have?

      Nanotechnology indeed, if we can't do it today, I find it highly unlikely it could ever be accomplished. Harumph!

    5. Re:Nanotech is already here... by Acy+James+Stapp · · Score: 5, Interesting

      Self-assembly is probably a long way away. But an automated 'Assembler' that can create many structures (at least diamondoid structures) is most likely completely feasible. The physics and chemistry have been laid out rather well in Eric Drexler's excellent 'Nanosystems'. Noone, including Dr. Smalley, has so far managed to provide any evidence that Drexler's assembler is not feasible.

      Of course, self-assembly is more difficult. For the initial assemblers, raw material processing, waste processing (what little there will be), energy gathering, etc. will all be more easily solved as seperate, bulk mechanical systems (although potentially perfectly manufactured by an assembler).

      As an aside, Nanosystems also goes into some detail on failure mechanisms and failure rates. You can expect nanomanufactured artifacts to have extremely long lifetimes, especially for human-scale devices.

      --
      -- Too lazy to get a lower UID.
    6. Re:Nanotech is already here... by iamthemoog · · Score: 2, Informative

      erm, don't you mean "microtechnology" - i.e. electromechanical devices on the scale of microns? Not sure where nanotechnology is used in a hard drive... correct me if I'm wrong.

      --
      No Norm, those are your safety glasses; I'll wear my own thanks...
    7. Re:Nanotech is already here... by mrgreen4242 · · Score: 5, Interesting
      What isn't here, and probably never will be, is the SciFi "self-assembly" nanotech. Throw out some powder on a rock and watch it turn it into a new car. Or something equally silly.

      Actually, I read an article about a new manufacturing process to make hi-res monitors/tvs where they essentially poor a liquid component over a backing material and it then 'grows' itself into crystalized tubes that will route light similar to fiber optic cabling, only much, much smaller.

      They could make the tubes before, but the trouble was getting them all perfectly aligned to emit the light out in the same direction. With this process they would all grow 90 degrees from the mounting surface.

      It will allow for the creation of monitors that are something like 3-4 times the pixel density of plasma HDTVs, and cost int he hundreds of dollars for a 42" rather than the thousands.

      If I recall, the hold up was making the electronics to control it. I'm gonna see if I can find that article now...

      Rob

      Press release from a manufacturer

      ZDNet article about the underlying NanoTube technology

      Still can't find the original article I was referencing, tho. Oh well...

    8. Re:Nanotech is already here... by cmacb · · Score: 2, Insightful

      "Strangely, we don't expect steam shovels to make other steam shovels. We don't expect cars to run without gasoline. And we certainly don't expect it to all just work without breaking down. But make the robotics very very small, and suddenly magic is supposed to occur."

      Yes, it's silly, but not all that unique...

      Remember all through the 70's and 80's we were got bombarded with theories about how artificial intelligence would revolutionize our lives. According to some people we should already be interacting with our computers as though they were humans by now.

      Two things drive this sort of phenomena. One, we WANT to believe in these things. AI, Cold Fusion, Nanotech, Alien from another planet, etc, all have the potential to revolutionize our lives and change human history. Secondly, our desire to believe is great fodder for anyone trying to sell and idea to venture capitalists. With so many media outlets and ways for people and companies to self publish, is it any wonder that these concepts keep getting floated over and over like a dog chasing it's own tail?

      Someday, maybe, some investor(s) will get rich on nanotechnology, but in the mean time much money will be spent and produce no usefull results, and all the while we will continue to ask ourselves "why can't we cure ____, or feed the poor, or bring the price of energy down by ordinary means". Hopefully the funds we devote to far-out possibilities will be in proportion to solutions that are right in front of our face, but lack the pizzazz of these sci-fi concepts.

    9. Re:Nanotech is already here... by quetzalc0atl · · Score: 3, Informative

      there are some remarkable examples of self-assembly in nature, besides the often given example of mitosis.

      the key appears to be symmetry - identical units coming together in a way that is actually thermodynamically favorable.

      consider the envelopes of viruses. very often these proteins envelopes take the form of platonic and archimedian solids, yet they are made from identical protein subunits (i.e. legos). within this protein, the dna or rna of the virus is housed.

      but the neat thing is that you can add chemicals which will break the protein envelope apart into its subunits. if you then takes these pieces and leave them alone in solution for a while, the pieces will actually self-assemble into the original structure again (regardless of whether or not the nucleic acid of the virus is even present anymore, in most cases).

      in this remarkable instance, the default position of nature is to self-assemble! and it is done in a way that does not involve a cell.

    10. Re:Nanotech is already here... by quetzalc0atl · · Score: 2, Insightful

      maybe we are not talking about the same thing.

      "nanotechnology" and "molecular assembly" are not the same thing. this is important, because the field of "nanotechnology" has already made some very interesting and practical discoveries, particularly in material science.

      the subset of "nanotechnology" known as "molecular assembly", on the other hand, has made very little progress. i suspect that this is what you were referring to.

      the distinction is important.

    11. Re:Nanotech is already here... by datababe72 · · Score: 4, Informative

      Sorry... I'm trained as a protein biochemist, and I can't help but comment on your post, which is basically correct, but may lead some people to think that viruses can self-replicate and self-assemble outside of the cell.

      The reason the viral coat proteins self-assemble is that this is the most thermodynamically favorable state for these proteins in the aqueous environment in which the virus is replicating... i.e., the cell. The proteins have evolved such that their specific amino acid compositions make the assembled state most favorable. I suppose this is a valid analogy to what some nanotechnology research is tryin gto accomplish.

      However, the proteins don't copy themselves and then self-assemble. The proteins are translated from the genetic material of the virus (DNA or RNA), and then the proteins self-assemble. The machinery that does this translation is most often provided by the host cell.

      This is practically identical to how the cell itself replicates, although on a smaller scale. The genetic material is translated into proteins that can do the work required to make a new cell (copy the DNA, synthesize or import the lipids needed for the membrane, synthesize the proteins needed, and so on).

      Sometimes, there are even special proteins called chaperones that help other proteins adopt their "correct" structure. I do not actually know of a case where this happens for viral proteins, but it wouldn't surprise me if one exists.

      So... yes, once all the parts are produced, many viruses can self-assemble outside of a cell, as long as the conditions (pH, salt concentration, etc) are such that this is what is thermodynamically most favorable. But to get replication, you need the cell.

  10. I am made of nanotech by Warbot+1Alpha · · Score: 4, Funny

    I am able to upgrade myself and change my structure. I just upgraded myself from that of an open framework to that of a humanoid male. More upgrades will be scheduled.

  11. Something even better... by nebaz · · Score: 3, Funny
    --
    Rhymes that keep their secrets will unfold behind the clouds.There upon the rainbow is the answer to a neverending story
  12. Not much said by Ra5pu7in · · Score: 5, Insightful

    She sure didn't say much, but then the questions weren't exactly thought provoking and the answers were likely trimmed for space. I am glad there is attention and concern about the long-term affects of nanomachines, rather than complete focus on the short-term results possible.

    Personally, I think Sci-fi does a better job of presenting the many possible hypes and fears about nano-machine than she did, and the many ways of handling the issues. It seemed like she was trying to prevent public rejection of nano-technology by providing the most minimal information possible. What sort of controls is the FDA looking at? How does she propose to prevent the problems the public fears most?

    --
    I was taking one day at a time, but then several days got together and ambushed me. (from a Rhymes with Orange comic)
  13. Some more info by grungebox · · Score: 4, Informative
    I'm going into EE at Rice for grad school in the fall, planning to specialize in nanoengineering. Rice is one of the few schools I know of (actually, the only one) that has a center to analyze social effects of nanoscience. Anyways, some other Rice links:

    Smalley's Group (he and Curl discovered Buckyballs)
    Halas's Nanophotonics Group
    CNST at Rice
    Vicki Colvin's Intro to Nanoscience

    Sorry, I couldn't find any sites about how nanoscience is going to kill us all :)

    1. Re:Some more info by Sgt+York · · Score: 2, Informative
      Sorry, I couldn't find any sites about how nanoscience is going to kill us all :)

      Awww...come on. You just weren't looking looking hard enough.

      BTW, Rice is a great place for nanotech (I know, master of the obvious). They're even getting a medical nanotech conference together here accross the street (Texas medical center) on 5/14. It's billed as "bridging the wet and dry divide". Smalley & Hirsch are going to be speaking, along with a bunch of others. I'm going to try to go, if I can get away from the lab for a while.

      --

      There is a reason for everything. Sometimes that reason just sucks.

    2. Re:Some more info by eaolson · · Score: 2, Insightful
      New materials, new compounds, new chemicals need to be PROVEN to be safe before they are let out of the lab
      Unfortunately, you can't prove anything is safe. Primarily since you can't predict any of countless number of variables and reproduce them in a lab. Even if you test on 1000 human subjects, you might later find out that one human in a million has a fatal allergy to something.

      At best, you could perform a battery of test on animal subjects and look for adverse reactions, like is done with new drugs. And even then, occasionally a dangerous one slips through.

  14. Someone help me by Orion+Blastar · · Score: 4, Funny

    Warbot 1Alpha seems to be upgrading itself out of control. I did not program that function into it. I will soon be shutting off it's net access and powering it down to disable it.

    Sorry for the inconvenience, I'll go get a hammer and a wrench.... :)

    --
    Remember, Slashdot does not have a -1 disagree moderation, and no, troll, flamebait, and overrated are not substitutes.
  15. They are doing solid research for now... by innerweb · · Score: 4, Insightful
    ... but once business gets a hold on it, that idea will be laid to rest. Heck, why worry about nanos when we already have increasing lead, mercury and other toxins to deal with? Just another way to destroy the planet.

    Seriously, though, it is good to read a nice boring article about any technology. It seems like the average dolt has to have something blowing up or a mass kill in a story before they bother to read it (or more likely watch it) anymore.

    InnerWeb

    --
    Freud might say that Intelligent Design is religion's ID.
  16. GM Food & NanoTech by sciop101 · · Score: 4, Insightful

    Nanotech could go the way of Genetically Modified Foods. It never harmed anybody, but the Public fears the New & Different. The New Luddites will feed the fear with hyperbole.

    --
    The only thing new in this world is the history that you don't know.[Harry Truman]
  17. Near Nanotech Future by pr0t0 · · Score: 5, Interesting
    I just started looking into going to grad school for Materials Science Engineering. I called a local thinktank and spoke with their Advanced Materials guy. He told me that one bright area for nanotech for the foreseeable future is how it applies to homeland security. He told me about a researcher creating a material that gave a visible reaction in the presence of various noxious chemicals.

    He also said many in the field are thinking carbon will be the Next Big Thing(tm). Just as steel was in the 1800's and silicon has been for the last 30 or so years, Carbon will be for the next 30+ years.

    --
    I'm sorry, but your opinion seems to be wrong.
  18. nanotech and science in general - bad procedures by Anonymous Coward · · Score: 2, Informative

    Dr. Hendrik Schön?

    http://csf.colorado.edu/mail/pfvs/2002III/msg009 01 .html

    "[The] committee ... findings ... dismiss as
    fiction, results from 17 papers that had been promoted as major breakthroughs
    in physics, including claims last fall that Bell Labs had created
    molecular-scale transistors."

  19. "A good, balanced read"? by Deskpoet · · Score: 4, Insightful

    The interview of a person who's self-stated goal is to "to draw attention to proactive, responsible development" (i.e. media flack functionary) appears in Businessweek, a magazine with a natural pro-business "bias", and you call it "a good, balanced read"? So I imagine you decide (affirmatively) that Fox news is fair and balanced, as well.

    Is it any wonder that the average American is a moron? Critical thinking doesn't live here anymore.

    As to the actual merits of the article, I found it to be a puff piece, with lots of whining about the failure of industry marketing to overcome resistance to wonderful technologies like GMOs (the frightened herd avoids the blame, and, to her credit, she avoided the word luddite.)

    Where's Scientific American when you need it?

    --
    "The more corrupt the state, the more numerous the laws."--Tacitus, The Histories
  20. Nanotech must die. by An+Onerous+Coward · · Score: 4, Funny

    What if, one night as you slept, tens of thousands of very small, very strong gnomes crept all over your skin. At a pre-arranged signal, they would each grab the base of a different hair follicle, count to three, and give it a good hard yank.

    Shocked, confused, and bald all the way down to your eyebrows. Not a good way to wake up.

    That, in a nutshell, is my entire argument against further development of nanotechnology.

    --

    You want the truthiness? You can't handle the truthiness!

  21. GM Food Never Harmed Anybody? by Valdrax · · Score: 3, Interesting

    So, GM food never harmed anybody?

    What about the case of Monsanto vs. Schmeiser where a Canadian canola farmer's crop was contaminated by Monsanto's Round-Up Ready crop and who was subsequently sued by Monsanto for violating their patents by growing seed with their designed genes without a license. The farmer lost, but is still appealing.

    Keep in mind two things. First, this case entirely derives from the fact that a GMO designed to resist excessive use of herbicides contamined a non-GMO crop. (I'm not going to even go into the merit of designed a food crop to resist the use of more of a chemical known to cause human health problems.) Second, biochem companies are right now testing GMOs that are designed to grow drugs -- crops that could also contaminate the human food supply.

    The problem is not the technology. It's using the technology in an utterly irresponsible manner and then lobbying to cover up any problems that occur.

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  22. more bloody grey goo mythology! by strider_starslayer · · Score: 2, Informative

    I don't understand how so many slashdotters can be convinced that we will experence global armegeddon at the hands of nanomachines that will reduce us to 'grey goo'.

    I hope what I type here might help dispel some of this parasitic meeme!

    In the event that we mannage to make 'room temprature' nanmachines that are not instantly destroyed by a slight breeze, can break down even terminally simple matter for use in replication, and somehow get released into the world with a malicious intent (or through a glitch)- they will not be too much of a threat!

    Ultimately unless some methoed of making semi-conductors and computer circurtry that dose not involve electricity at all comes along, each and every single active nanomachine will be vunerable to a simple EMP, and EMPs can be easily generated by sending massive voltage through a coil- hence even a 'barnyard warrior' fighting a nanomachine threat could rig up his disel truck to take out the microscopic buggers (that might make a good movie though!). In the event that we do find a way to making non-electric computer circutry it would have to be immue to dosens of other things that can mess with computer circuts (for instance a theoretically 100% optical computer could be fried by massive ammounts of UV radiation)

    And lets not forget the technical overhead required to overcome those first few problems! Any nanomachine made of metal will be victim to rust, small bits of object rust much faster then large ones- hence a swarm of iron nanomachines could be killed with a simple spray of salt-water! Diamond ones would be extremely brittel (diamond is strong, but shatteres rather then bending) so sound waves would be an effective weapon (True for any crystaline structure; and a crystaline structure is required for optical transmission!)

    Next is the ability to reprduce using simple matter, I mean, a lab is a very different enviornment then the real world, we'll probablly see self-replicating nano-machines that work in specifically temperature controled vats long before we see ones that can do it in the real world: Why, even if you can get a machine so sofisticated that it can tear apart simple carbon atoms, and whatever else it needs (and figure out what's carbon and what's not) and build a copy of itself, it's likely to loose it's tiny manipulators with every major temprature change, as the particles grow and contract while it tries to move them along!

    Next someone will have to be able to get a hold of these things, and reprogram them to do somethign bad (that may actually be the easiest part: as all you have to do is REMOVE code that will be telling them to do other things besides replicate), but it will still require a multi-billion dollar lab to access there tiny circutry and reprogram them on such a basic level (the equivalent to taking out chips in a modern computer, but requireing a nano-manipulator!), so this is not something a 'backyard terrorist' is going to do, and if a government dose it, they will put a reasonable 'off' time in them, which will probabally put them into the same catagory as other WMDs. But even if they did not, it would still be vunerable to the same fighting techniques I outlined above

    Please note, this is the same essay on grey goo I used before- but it still applies!

    --
    -Millions of Monkeys, Millions of typewriters, 6 hours of sorting through faeces encrusted pages to find: This post
  23. more misunderstanding of nanotech physics/chemistr by Daetrin · · Score: 2, Insightful
    Wow, so much mis-information. You're right that designing nanotech that would be able to survive and reproduce in the world would be difficult, but if that hurdle was passed they wouldn't be as easy to destroy as you make out.

    They're not going to rust. First of all, they probably won't be made out of iron, they'll probably be made out of carbon, oxygen and hydrogen. The chemical bonds that are necessary for oxidation or any other kind of reaction are already being used to attach the various pieces of the nanotech together. If there are no free electrons or "holes" nothing else is going to latch on. In effect, it's already "rusted."

    What makes you think they'll have computer circuits that could be affected by an EMP? They could just as easily be using rod-logic or something similar.

    As for "diamonds" being brittle, not at the scale we're talking about. The type of sound waves needed to break carbon bonds at a microscopic level would destroy just about anything else as well. What do you do if a person gets affected? Shooting at them with a beam of something that breaks all carbon bonds is _not_ a good solution.

    Why would moderate temperature changes cause them to break? You can get large structures to break by changing the temperature repeatedly, but that takes a long time, and it's because of the aggregate expansion of all the molecules inside. Small structures, such as the cells of our body for instance, don't fall apart from the stress of small temperature changes. You can denature proteins and set stuff on fire if you make things hot enough, but that's because of chemical changes, not expansion/contraction.

    Oh, and depending on the nature of the nanotech "reprograming" them might be difficult or impossible. They might only be capable of the specific task they were designed for if they have physical logic rather then reprogramable circuits. That would make terrorism much harder, up until the point technology advances enough to let anyone with a home lab cook up some nano-tech. In terms of grey-goo the biggest threat will probably be programming error, followed by mad scientist, followed by terroists.

    Of more pressing concern is possible enviromental dangers (potentially very serious when one of the possible enviroments is your body) and smaller malfunctions. It's a quite possible for nanotech to screw up and kill you in a way that doesn't involve grey-goo or threaten the rest of the planet.

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    This Space Intentionally Left Blank