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Regenerated Nerve Cells Let Rats Walk Again

SteamyMobile writes "Paralysis by spinal cord injuries through accidents must be one of the most horrible life-altering experiences imaginable, often affecting young, active people, and so far there has been no effective treatment of it. Researchers at the Miami School of Medicine have found a therapy involving regenerating nerve cells to cross the gap in the spinal cord. 70% of rats could walk again after the therapy. Hopefully this could benefit Christopher Reeves and thousands of others who have had their lives changed so much by spinal injuries."

17 of 46 comments (clear)

  1. not to nitpick by trs9000 · · Score: 2, Informative

    i dont mean to nitpick but the gentlemans name is Reeve. no 's' on the end.
    the site you linked to makes that pretty clear.

    1. Re:not to nitpick by MachDelta · · Score: 4, Funny

      This is Slashdot. Not even the submitters read the articles.

  2. Statistics by HalfFlat · · Score: 4, Informative

    Just a heads-up on an error in the summary: the Wired articles states than (all) the rats which received the combination treatment regained 70% of their walking function, not that 70% of the injured rats became able to walk.

    Given that the improvement was over a period of just eight weeks, this is possibly even more promising than the mangled statistic in the summary.

  3. Oh Geeze... by thecampbeln · · Score: 2, Funny
    Just call me a jackass... the first 3 times I read that, I saw "attractive", not "active". Durr... Excuse me whilst I make a quick trip to the coffee pot to get an eye opener.

    "Moo, Moo. Moo Moo Moo Moo" (Translation: "Sorry, my bad.")

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  4. Re:WTF? Only Hot People Apply? by jgaynor · · Score: 4, Interesting

    ...often affecting young, active people...

    Actually Im a big dork and sustained a fairly dork-related injury which this could help. During finals of my senior year I stressed myself out so badly that I incurred the wrath of Ramsey-Hunt syndrome - think of it like chicken pox in your brain. It cuts off the cranial facial nerve and paralyzes one side of your face. The nerve regrows but is almost never 100% again. Id love to get this fixed so my smile won't be so f*ed up anymore. I only hope when this technology hits the open market it's not tens of thousands of dollars and will work on non-spinal nerves.

  5. Math proves Christopher Reeve will walk again! by Anonymous Coward · · Score: 5, Funny

    A rat can carry around a kilo when it is healthy. I would assume that these 70% rehabilitated lab rats can carry 700 grams. Assuming Chris has lost some weight since the fall and he now weighs 70 kilos, it will only take the combined effort of 100 of these rats for him to walk again!

    Throw in one 'super rat' that tells the other rats what to do, and Segway has some serious competition...

    1. Re:Math proves Christopher Reeve will walk again! by Anonymous Coward · · Score: 3, Funny

      Assuming Chris has lost some weight since the fall and he now weighs 70 kilos, it will only take the combined effort of 100 of these rats for him to walk again!

      Scientists have already figured out how to do this with cockroaches; unfortunately it only allows crippled people to be mobile in the dark. If you turn the light on really fast they slam you right into the fridge.

    2. Re:Math proves Christopher Reeve will walk again! by Paradise+Pete · · Score: 2, Funny
      What if you turn the light on really slowly?

      They still slam you into the fridge, but you see it coming.

  6. Re:biotechnology vs. bioethics, by a quadriplegic by ScriptGuru · · Score: 5, Interesting

    This is far different from the stem cell research sung about. This is taking healthy Schwann cells from peripheral nerves which regrow which can be taken from the same animal. I don't see how there is really any ethical problem here.

    --
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  7. Superman no walkie by martinX · · Score: 4, Insightful

    The original research mentioned in the article was done in the hospital where I work, and I become very familiar with the material - I made the Flash-driven CD-ROM press release (first time I used Flash video) :-) . Since I come from a life sciences background, it didn't go whooshing over my head. Bottom line: this sort of treatment, if the patients are to have any chance of succeess, must be used within about 30 days of the injury occurring. Superman will not fly.

    The treatment still hasn't been used to treat spinal cord damage in humans. Phase 1 trials (where they see if there are any negative effects from the treatment) were carried out in our hospital last year. It'll be a while before they move on to Phase 2.

    --
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    1. Re:Superman no walkie by DigiShaman · · Score: 2, Interesting

      So why not cut thin slices of cord on both ends of the broken cord? I would think newly exposed spinal cord would help jumpstart the ability to be treated once again.

      --
      Life is not for the lazy.
  8. chistopher reeve is screwed by maddh · · Score: 4, Interesting
    I saw some spinal injury expert interview on the news a while ago when the stem cell controversy was bigger and christopher reeves had that commercial where special effects made him stand up. The expert said that when the spinal cord is severed, after a certain period of time the spinal cord below the cut turns to mush cause it doesn't get used. basically saying that people with old injuries were screwed and the best medicine could hope for is treating people right after the injury. So while these rats have only a .1 mm gap to regenerate, christopher reeve could very well have 3 feet of spinal mush along with peripheral nerves that would need regeneration.

    But then again he wiggled a toe and breathes on his own now so i might be wrong.

  9. Re:WTF? Only Hot People Apply? by DiscoOnTheSide · · Score: 3, Interesting

    Wow Jon. I'm 110% serious when I say I never noticed it in the two years I've been working at ResNet with you (this is A.J.)... See you at work sometime...

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  10. Re:Remember one simple little fact by m0rph3us0 · · Score: 3, Insightful

    Why not protest rat poison before research? I'm just guessing rat posion kills a hell of alot more rats than research.

  11. Re:biotechnology vs. bioethics, by a quadriplegic by Anonymous Coward · · Score: 3, Funny
    I hope these particular scientists somehow found rats with existing critical injuries

    If I could get out of this chair I would kick your ass up and down Main Street.

  12. Other applications? by Alsee · · Score: 2, Funny

    Does this treatment work in the brain as well? Can it help Bush?

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  13. Re:Remember one simple little fact by Kozar_The_Malignant · · Score: 4, Insightful

    >somebody had to cut the spinal cords of those rats in the first place for the experiments... and then they were killed to examine the results

    Duh! They're RATS, not human beings. Without animal testing of drugs and surgical techniques, life would still be pretty damn medeival. If you want to go back to the days when people loved having hordes of rats in their dwellings and you got burned at the stake as a witch if you kept a cat, please do, but do it on some other continent from the one I live on.

    >Please remember this and ponder if the ends justify the means.

    It is good to keep this in mind, and I strongly oppose cruelty to animals, but in the case of biomedical research, the ends absolutely justify the means.
    --
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