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Couch-Potato Gene Found In Mice

syousef writes "Good news for those of us who are prone to putting on weight sitting in front of a computer screen. The Sydney Morning Herald is reporting on research which shows that changing a single gene in mice turns them from couch potatos into super-athlete mice that don't get fat and are able to run for hours. They believe this has the potential to lead to a pill to turn similar genes on in humans. From the article: '"It is a pill that, in part, mimics exercise. It mimics the metabolic activity associated with exercise," said Ronald Evans, of the Salk Institute for Biological Studies, who led the study. Writing in the journal Public Library of Science Biology, Dr Evans and colleagues said they tweaked the PPAR-delta gene to stay in a permanently "on" position and then genetically engineered mice with it. They expected to see changes in metabolism but were surprised at how extensive they were.'"

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  1. Re:is this the same as by Jesrad · · Score: 3, Informative

    Hmm, no. The link you provide talks about a way to deprive monkeys of the "satisfaction of work done", so they keep working and working because they never "feel" their work is done. It acts on the pleasure/reward circuit in the brain.

    The pill discussed in this here article, though, is about forcing the metabolical effects of exercise (developing of muscles, turning of fat into readily-usable energy, etc...) without exercising. It acts on the metabolism.

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