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Genetic HIV Resistance Deciphered

hexed_2050 writes "Researchers have pin-pointed the reason why some people have a greater immunity, or in some cases, total immunity to the HIV virus. They credit a genetic defect that can be traced back to Europeans in the middle ages."

4 of 64 comments (clear)

  1. Well.. by WhatAmIDoingHere · · Score: 2, Insightful

    You scratch a living out of the mud and shit and you're going to end up immune to something..

    Kinda like people who work at hospitals, they usually never get sick enough to miss a day of work due to catching a little bit of everything while working.

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  2. Carefull Now by WaZiX · · Score: 3, Insightful

    These genetics mutations are quite rare (1%) and the delta32 Mutation only protects strains of HIV that use CCR5 proteins to help them break into the cells, so yes a very few people are immune to most strains of HIV. And this is why doctors will prbably never allow people get tested for delta32 mutation.

  3. Re:Future evolution by angel'o'sphere · · Score: 3, Insightful


    The number of people who die from AIDS is a very strong selection pressure. Unless the epidemic is halted medically, we can expect that it won't be many generations before these mutations are nearly universal.


    What is many generations in your sense? 10? 100?

    Seriously, you have some simple stuff about how selection works misconcepted.

    No selection when:
    o as long as one who dies on AIDS already has children
    o as long as one who has AIDS fathers or mothers a child
    o as long as one who is not ill and has not the gene gets a child

    A gene can only spread via selecion if all other individuals in a population suffer from not having the gene.

    Currently a minority suffers. Having the gene or not does not influence "breeding" and thus there is no selection happening.

    If at all teh selection is happening in reverse, the virus is adapting itslef to become less letal. Because while one human is dying the virus runs through 1000nds of generations.

    angel'o'sphere

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  4. Re:Defect? by St.+Arbirix · · Score: 2, Insightful

    How about sickle-cell anemia?
    It has its problems but it also makes you immune to Tse-Tse flies.

    Our sense of "art" or creativity is supposed to be the result of some mutation a long time ago. It lets us solve some truly incredible problems (esp. when compared to animals) but also opens us up to all sorts of bizarre mental disorders. Defect?

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