Technology to Help with Learning Disabilities?

GotSanity asks: "I have a little brother who is now 18 and still can not read or do basic math. At an early age he was diagnosed with a level 10 mental handicap. I am curious as to what technology is available to help teach him to read. The major problems with most educational software I have found is that they both cater to younger minds (even though he has a learning disability he still is involved with everyday teenager activities like video games and music) and are often far to expensive for a working class family. I originally got him a copy of Typing of the Dead, and through it he has been learning to read and spell better. What novel education ideas can the Slashdot community suggest?"