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Gene Therapy Ages Human Cancer Cells in Lab

mattr writes "Korean scientists are the first in the world to selectively age off and kill human cancer cells, by injecting a gene that suppresses telomerase, a cancer-specific enzyme that normally makes cancer cells immortal by protecting the telomere tips of their chromosomes. The telomere length modulation mechanism was found by two scientists from Yonsei University and colleagues at U. Central Florida, and is reported in the April 1 issue of Genes and Development magazine."

4 of 318 comments (clear)

  1. Cool.. but some questions. by daquake · · Score: 4, Insightful

    This is incredible in theory, but what time frame are we talking about in humans once this gene is injected? Will it adversely affect human cells? I read it targets a cancer specific enzyme but am I missing anything? Could this be a cure, after the fact? (Bio-Medical newbie here).

    --
    Be True, Unbeliever
  2. Obvious question by ChuckSchwab · · Score: 5, Insightful

    If telomerase makes cancer cells immortal, is someone working on a way to make, uh, non-cancer cells immortal?

  3. Re:Fertility is a big problem by ag0ny · · Score: 4, Insightful

    Infertility is also a side-effect of, well, being dead because of cancer.

    If you were given the choice between being alive but infertile or being dead, which one would you choose?

  4. Re:who gets credit by Anonymous Coward · · Score: 5, Insightful

    I know it sounds very progressive to make those sort of assertions, but they don't have much merit. Anyone with even a rudimentary scientific background will tell you that key scientific breakthroughs come from all over. As a matter of fact, in the past few years there has been a considerable amount of concern within the American scientific community over the lag in American research and publication. Research just isn't a priority anymore in America, and we are beginning to feel the effect.

    My guess is that the Korean scientists will keep their credit, just like the Koreans scientists who recently successfully generated stem cells from somatic adult tissues, just like the Dutchman who came up with the microscope, just like the Moravian monk who counted peas, just like the Swede Botanist retained credit for the Linnaean classification, just like the Russian Chemist retained credit for the periodic table, just like 10th century Arabs retained credit for much of Algebra, just like citizens of Greek city-states retain credit for beginning to formalize reason.

    The capacity for human genius is universal, and in the reality based community known as science, we appreciate that. It belittles the intellects of foreign researchers and the hard work of American scientists to say otherwise.