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Nanotech Trojan Horse That Kills Cancer
An anonymous reader writes "University of Michigan scientists have created the nanotechnology equivalent of a Trojan horse to smuggle a powerful chemotherapeutic drug inside tumor cells - increasing the drug's cancer-killing activity and reducing its toxic side effects." From the article: "The drug delivery vehicle used by U-M scientists is a manmade polymer molecule called a dendrimer. Less than five nanometers in diameter, these dendrimers are small enough to slip through tiny openings in cell membranes. One nanometer equals one-billionth of a meter, which means it would take 100,000 nanometers lined up side-by-side to equal the diameter of a human hair."
Sure, this might make you feel uncomfortable, but guess what will make you feel even more uncomfortable? Having your body bombarded by potentially levels of radiation so high that it is potentially fatal.
There are so many ways to improve upon killing humans. Is one more way really worth worrying about? So someone has found a better way to diliver a chemical payload into a human cell. Certainly I bet someone can figure out how to make said payload lethal. Who cares though? We already have chemical and viruses sitting around that can kill within seconds. It is like worrying that some nation went from owning 5000 to 10,000 nuclear weapons, or worrying about getting shot 100 times rather then 50. If genocide is your goal, the tools are already avaliable.
I personally am excited at the prospect of a new treatments like the one outlined. Dead is dead. You can throw HF in my face or you can throw your nano-poisonin my face. Either way, the outcome is the same. On the other hand, nanomedicen is not chemo. Chemo has the potential to be almost as bad as the cancer. If a nanomedicen can kill cancer and do less harm to my body, I am all for it, paranoia be damned.
Viruses, bacteria and cancer are also all "provided" by nature....
Analogies don't equal equalities, they are merely somewhat analogous.
Finally, nanotechnology exists in nature. Arsenic is natural, many natural plants are poisonous, along with various animals, fish, insects, etc. The natural surface of Venus is lethal, you can't live underwater, falling off a cliff is natural.
Crazy Luddites.
Currently hooked on AMP
As a person recently diagnosed with cancer and currently in chemo, I find more than passing interest in this story. Although, very clearly the approach described here isn't going to help me, I've spent a lot of time researching cancer therapies of various types and I feel qualifed to comment.
Cancer isn't one disease, it's a group of related diseases. A solution that works for say breast cancer may or may not work for other cancers. The idea of targetting cancer cells specifically for apoptosis (cell death) isn't new but the idea of using a delivery vehicle that can have a deadly payload seems to be somewhat novel.
There are a number of other drugs in development that might have a similar effect. Also there are human clinical trials already in progress for methods of creating a vaccine tailored to a specific person by using that person's tumor. Given that a phase 1 trial of the approach described in the article will not start for two years and that trials generally take at least 7 years before approval, it's likely that other equally novel delivery methods will be approved substantially before this one. This approach will have to show it's better than the others that will be on the market already when approval time comes along.
With some popular cancers such as breast and colorectal cancers, it's quite likely that there will be better therapies. However, if this approach can be targetted to the really deadly cancers (like lung and ovarian cancers) or the many cancers that don't have any good treatment options, this could be a real winner. If you can wait long enough before getting your disease.
something about the process makes me feel uncomfortable.
Try having cancer.
you can have my violent video games when you pry them from my cold, dead hands.
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