Scientists Grow Blood Vessels Using Skin Cells
rubberbando writes "The new york times is running a story about how scientists have discovered a way to grow new blood vessels using skin cells. Since the blood vessels are grown using the patient's own skin cells, there isn't any chance for rejection. This looks to be quite a boon for people who have several damaged blood vessels from diseases such as diabetes. Perhaps one day they will be able to apply this technology/technique to creating other parts of the body and rid us of the whole stem cell controversy. Only time will tell."
I doubt that it'll rid us of the controversy... because by the time that becomes possible, cloning or genetic modification of some other sort will also have also become possible, and that'll just pick up where the stem cell controversy left off, probably with many of the same arguments on both sides.
We can't get rid of something that's projected onto the situation by people who are nervous/scared about what the bio-sciences say about their world view. The stem cell worriers aren't really worried about stem cells or their source, they're worried about how close we're getting to a comfortable understanding of cellular mechanics. That takes the mystery out of a lot things, and devalues mystical explanations (and those social institutions that rely upon them for clout).
Growing new body parts out of other body parts will still freak out a certain number of people, no matter what. If it's not the stem cell faux-controversy, it will be the "only rich people can afford this treatment, so it's evil" crowd or their various other counterparts.
Don't disappoint your bird dog. Go to the range.
Maybe we can grow steak this way too .. in large vats. Get rid of the animal rights issues that way.
Yumm.
This has been done before--by cancer.
Just the other day in my cancer seminar (biomedical engineering department at UC Irvine), we were discussing angiogenesis, which ordinarily occurs when tumors have an imbalance between angiogenic growth factors and inhibitors. (Usually arises when tumors become too large to receive their nutrients soley from diffusion through the tissues.) The resulting gradient in these chemical signals recruits endotheial cells (the cells that ordinarily form the walls of blood vessels) to move chemotactically towards the tumor, align themselves, and form a new blood vessel to supply nutrients to the previously hypoxic tumor.
But in some tumors, the tumor cells themselves align and form blood vessels, with no need for endotheial cells. Much like forming blood vessels from skin cells.
The human body is truly an amazing machine. The fascinating part about cancer is that you get to see many of the mechanisms at play, and what happens when they're out of balance. -- Paul
OpenSource.MathCancer.org: open source comp bio