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Living Photos Use Bacteria as Pixels

BrainBlogger writes "Scientists at UC San Francisco have engineered bacteria to create living photographs that weigh in at 100 megapixels per square inch. The photos were created by projecting light on "biological film" -- billions of genetically engineered E. coli growing in dishes of agar."

30 of 156 comments (clear)

  1. Students discovery? by dada21 · · Score: 4, Interesting

    Obligatory Coral Cache Link

    Pretty detailed tiny image of the Flying Spaghetti Monster. How many noodly appendage comments will we see?

    With the growing number of sequenced microbes, we can search through nature's large trove of tools to find ones that fit the job," Levskaya said. "In our case, searching for light-sensing domains led us to use a photosynthetic bacterium." The students produced ghostlike, living photos of many things, including themselves and their advisors

    I wonder how far they are from being able to take a huge image of a processor chip pathway and use these microbes to lay out an eating path for another microbe to create cheaper chips. I'm guessing it isn't realistic in the near future, but as the progression builds towards more "consistent" bacteria, maybe we'll see more aggressive use of these discoveries for profitable reasons.

    That's my biggest question -- is anyone seeing private R&D scientists investing time and money in engineered bacteria that will be protected by patents or other IP protections? It's pretty amazing that TFA's discovery was by students.

    1. Re:Students discovery? by websaber · · Score: 4, Funny

      The Flying Spaghetti Monster http://en.wikipedia.org/wiki/Flying_Spaghetti_Mons ter appears in living material and you attribute it to "Science" and "Bio-business". He is talking to us and we are just to cynical to listen. For shame. We must fight for the minds of tommorow or there is no hope.

      --
      "A good friend will bail you out of jail. A true friend will be sitting next to you saying, 'damn....that was fun!'"
    2. Re:Students discovery? by ottffssent · · Score: 2, Interesting

      These bacteria are way too big to be of any use in modern photolithography. Assuming each one's square, and there's 1 per pixel, each bacterium takes up an area of about 6.5 square microns (1 100-millionth of a square inch). For comparison, the smallest production SRAM cell I can find is .25 square microns, and contains 6 transistors. That makes these bacteria 150x as big as a transistor, and even larger when compared to the features that make up the transistors and connect them together.

      Now, in situations where you want a physically large product, such as the circuitry to drive an LCD, biology holds huge promise.

  2. Not surprising by roman_mir · · Score: 3, Funny

    Living Photos Use Bacteria as Pixels ...
    Nothing for you to see here. Please move along.
    ---
    Can't see nothing with those bacteria sized pixels!

  3. Respect life by Anonymous Coward · · Score: 5, Funny

    That bacteria has every much of a right to life as you! Boycott anti-bacteria soap and walking!

    Who do some people think they are--the pinnacle of creation, or something?

  4. Hmmm. by cocoamix · · Score: 5, Funny

    So that's what an intelligently designed life-form looks like.

    1. Re:Hmmm. by Yocto+Yotta · · Score: 2, Funny

      That, you heathen, is the image of Jesus' father. Get with the times.

      --
      A B A C A B B
  5. Mmm. by dslauson · · Score: 4, Funny

    Who wants to be the first to flip through my E.coli scrapbook?

  6. Remember.... by TeaQuaffer · · Score: 4, Funny

    To wash your hands and don't touch your face after using your camera.

    --
    Sola Deo Gloria!
  7. Ecoli coating by Belseth · · Score: 4, Funny

    Great, now you can get Montezuma's Revenge from a photo.

    1. Re:Ecoli coating by nizo · · Score: 4, Funny

      Plus now you really can go blind from looking at naughty pictures.

  8. dirty pictures by hosecoat · · Score: 4, Funny

    so now there is a new kind of dirty picture. The internet will thrive!

  9. E. coli!? What happens if... by GecKo213 · · Score: 2, Funny

    ...my child gets a hold of the negatives and eats them? E. coli poisoning!? No thank you!

    --
    Generation Trance: What generation are you?
  10. Hail Thy Holy Noodley Appendage! by Bananatree3 · · Score: 2, Insightful

    I have seen His Holiness himself! Bacteria in the form of Him?!? This most certainly is the work of Thy Holiness! How else could this be possible? Most certainly His own work. These students have been Touched by his Noodely Appendage! (faints)

  11. Obligatory Jokes by thewiz · · Score: 4, Funny

    That picture of you will really grow on someone!
    Watch as the eyes of the picture really do follow you around the room!
    E. Coli never looked so beautiful!

    --
    If "disco" means "I learn" in Latin, does "discothèque" mean "I learn technology"?
  12. why is this interesting? by penguin-collective · · Score: 5, Interesting

    E. Coli genetic engineering has been around for many years. Creating light sensitive strains, strains that make pigments, etc. is roughly appropriate for college level biology. I suppose it's kind of neat that engineers have taken notice, but it really is textbook stuff.

    In fact, even more simply, since the pigment was present/absent based on whether the bacteria were growing in the light, you can repeat this experiment at home: use any organism using chlorophyll for photosynthesis and grow it in patterned light: you'll get a "photograph" in green/yellow. That's an experiment even elementary school students do.

    You've got to give it to these people, though: they are excellent salespeople. Getting away with such trivialities as "engineering" and endowing bacteria with "new skills" takes both guts and skills.

    1. Re:why is this interesting? by swiftstream · · Score: 2, Interesting

      Uhh, in case you didn't RTFA, this _is_ college level biology. The team that genetically engineered the bacteria was led by a grad student.

      --
      Be a PATRIOT--because the only thing we have to fear is the lack thereof.
  13. Re:*Ducks* by evil+agent · · Score: 4, Funny
    That photo sure grows on you doesn't it?

    Yeah, it's so life-like.

    --
    End transmission.
  14. New Scientist by alanw · · Score: 4, Informative
    Plenty of bandwidth over at New Scientist

    Complete with a photo of His Noodly Holiness.

  15. Using E.Coli as pixels? by Stonent1 · · Score: 2, Funny

    That's pretty shitty.

  16. Hellooooo blogvertisement by SuperBanana · · Score: 3, Interesting
    "Adapted from a press release" indeed. WHOIS for brainblog.com:
    Administrative Contact: Elabridi:, Mounir mounir@yahoo.com Maroc Internet SARL 221 Boulevard Zerktouni Casablanca, 20010 Morocco 17202492499 Fax --

    Third google hit on Mr. Elabridi's name is:

    "Maroc Internet - Management Mounir Elabridi, a globally recognized innovator in Internet marketing, founded Maroc Internet in 2002. Mr Elabridi brings to this venture a proven track ...

    Well, now how about that.

    The domain name servers for the domain are NS1/NS2.BENSULLIVAN.COM. Mr. Sullivan lives at 4404 Price St, Los Angeles, CA 90027- about a 15 minute drive from University California Los Angeles. It's a stretch, but also an interesting coincidence.

  17. webcast of the lecture is here! by dokebi · · Score: 3, Informative

    He gave a talk at the Synthetic Biology seminar at UC Berkeley two weeks ago. The web cast is located here:
    http://webcast.berkeley.edu/courses/archive.php?se riesid=1906978261
    It's titled "Programming Dynamic Function into Bacteria"

    --
    In Soviet Russia, articles before post read *you*!
  18. Beware by Profcrab · · Score: 5, Funny

    "Mooooom, the picture of Billy is eating Billy."

  19. Original link please by caseih · · Score: 2, Insightful

    Where I can I find the original story? This is interesting to me, but I'd rather not be maniupulated into driving traffic to some blog site like Mr. Roland Piquepaille likes to do (haven't seen any of his posts in a while, thank goodness). Not trying to troll here.

    1. Re:Original link please by spage · · Score: 3, Informative

      The lab's home page is http://www.voigtlab.ucsf.edu/ , but they don't have a news item for this yet. The work seems to be Engineering E. coli to see light and will be in Nature according to their Papers section.

      The most recent presentation slides (PDF) are a hoot, that talk must have been fun.

      Go UCSF!

      --
      =S
  20. I have a cold by Linker3000 · · Score: 4, Funny

    AAAAAaaaaaTTTTCHHHHHHHHHHHOOOO

    Hey, my 24 exposure roll of 35mm film just became 26 exposures!!

    --
    AT&ROFLMAO
  21. Interesting. by jd · · Score: 4, Informative

    For images that are essentially monochromatic, this is fine. Actually, a Russian photographer did some ingenious colour photography using monochrome film, but that was sensitive to all frequencies not just one.

    --
    It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
  22. Scientists create "chemical image" with molecules by GrahamCox · · Score: 4, Funny

    Scientists have announced that they have managed to create a gigapixel per square inch "light sensor" using only silver halide molecules coated onto a transparent plastic substrate. On exposure to light, some molecules change state by dissociating into pure silver. Exposure times of just a few milliseconds were all that were needed. This image is not visible to the naked eye, but can be "developed" using chemical processing to amplify the image to make it visible. The final image can be then fixed and rendered no longer light sensitive by bleaching out the remaining halides. The image is then rendered permanent. With its vastly higher resolution than ordinary digital CCD sensors, scientists are hailing the discovery as a breakthrough for creating ultra-high resolution images. They have also speculated that by creating a sandwich of light sensitive layers and colour filters, colour images could be recorded by the same process. The only question is, is the usual digital imaging that we have all grown used to doomed by this new process?

  23. He thought of it first... by sokweman · · Score: 2, Interesting

    Interestingly, the idea of using microbes to create an image is not new. Alexander Fleming, the discoverer of penicillin, was a member of the Chelsea Arts Club by virtue of paintings he made by growing different colored bacteria. http://en.wikipedia.org/wiki/Alexander_Fleming

  24. 12 to 15 hours of exposure :) by carlmenezes · · Score: 2, Funny

    smile...
    keep smiling...
    *15 mins later*
    keep smiling....
    *half an hour later*
    keep smiling...DON'T MOVE!
    *3 hours later*
    keep smiling...I SAID DON'T MOVE. I DON'T CARE IF YOU'VE GOT CRAMPS!!
    *8 hours later*
    hey! we need your eyes open! you can't fall asleep! and SMILE!
    *12 to 15 hours later*
    there! all done! Your living photograph is ready.
    Now let's start on the family portrait now that you've had some practice.

    --
    Find a job you like and you will never work a day in your life.