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Researchers Identify Gene Involved in Regeneration

v1x writes "Researchers at the University of Utah School of Medicine have discovered that when a gene called smedwi-2 is silenced in the adult stem cells of planarians, the quarter-inch long worm is unable to carry out a biological process that has mystified scientists for centuries, regeneration."

4 of 134 comments (clear)

  1. Logic 101 by n0dalus · · Score: 5, Insightful

    ... when a gene called smedwi-2 is silenced in the adult stem cells of planarians ...

    That doesn't mean the gene has anything to do with it's regeneration.
    If you silenced a gene in me that allowed me to produce red blood cells would you then say you had found the gene responsible for me being able to respirate (live)?

  2. illusions of you by Xiph · · Score: 5, Insightful

    This article comes close to saying that we'll have this in humans soon, probably to keep you interested. Let me set this straight, you won't be able to get a cool regeneration ability.

    a. we don't know how this would work with the rest of the human genome
    b. we have rules against testing a
    c. the technology isn't complete for changing a humans dna
    d. we have rules blocking a lot of research into c
    e. It would be cool, so it's not going to be publicly available.

    On the other hand, this is interesting research, and could help a lot in several fields of medicine, though i believe it would be mainly transplant medicine, and anything usable is still 10-20 years into the future. So get your hopes up for your kids, but realize this, you will die the same way as your grandparents.

    --
    Blah blah sig blah blah blah irony blah blah
  3. Finding one gene alone isn't the key by Frangible · · Score: 4, Insightful

    Regeneration is a very complex process and its behavior is not governed by a single gene or protein expression, as it involves a variety of very complex mechanics that are not fully understood. While I'm sure this gene is responsible for part of the regenerative process in worms, simply eliminating one gene and breaking something doesn't mean this is going to translate into a human response. Regeneration research has been going on for many years, and it has produced limited results in rats as some of the mechanics responsible have been found. Further, stem cells don't play the only role in regeneration in more complex animals similar to mammals like the newt; the first step of regeneration is muscle cells dedifferentiating and then differentiating into a new replacement cell type. There are multiple proteins (and multiple genes) involved with this step alone, and it's one of many.

  4. Re:Reality? by rubycodez · · Score: 4, Insightful

    I'd take a functional but somewhat non-matching limb over no limb or prosthetic limb any day of the week. And you can always lop the extra ones off.