Finding a Needle in a Haystack of Data
Roland Piquepaille writes "Finding useful information in oceans of data is an increasingly complex problem in many scientific areas. This is why researchers from Case Western Reserve University (CWRU) have created new statistical techniques to isolate useful signals buried in large datasets coming from particle physics experiments, such as the ones run in a particle collider. But their method could also be applied to a broad range of applications, like discovering a new galaxy, monitoring transactions for fraud or identifying the carrier of a virulent disease among millions of people." Case Western has also provided a link to the original paper. [PDF Warning]
Whether you "know" or not is always up for debate, but that's usually for epistemology class. In classical hypothesis testing in statistics, you make a distributional assumption about your data, and then calculate a probability from the data you observed (the p-value) given your initial assumption. If this probability is very low (also an interpretation), you assume your initial distributional assumption was incorrect. There are finer points to it of course, but classical hypothesis testing in statistics is pretty much a reductio ad absurdem in logic.