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Tumor Suppression Gene Discovered

An anonymous reader writes ScieceDaily is reporting that researchers at Ohio State University may have identified a new and unusual tumor suppression gene that could effect cancers of the lung, head, and neck. From the article: "The gene, known as TCF21, is silenced in tumor cells through a chemical change known as DNA methylation, a process that is potentially reversible. The findings might therefore lead to new strategies for the treatment and early detection of lung cancer, a disease that killed an estimated 163,510 Americans in 2005. The study could also lead to a better understanding of the molecular changes that occur in tumor cells during lung-cancer progression."

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  1. Nothing new to see, move along... by InternationalCow · · Score: 4, Interesting

    Another example of researchers drumming up their findings. Altered methylation patterns of tumor suppressor gene promotor sequences is nothing new. Neither is the finding of a gene whose product can act to suppress tumor growth. There are many of those.Posting this on slashdot is somewhat overdone. DNA methylation is an exciting target for chemotherapy, that will doutblessly benefit cancer patients in the near future. But it is too early to cry victory.

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